STRINGSTRING
AFW92837.1 AFW92837.1 eda eda AFW92963.1 AFW92963.1 rpe rpe AFW93028.1 AFW93028.1 AFW93210.1 AFW93210.1 AFW93394.1 AFW93394.1 nagB nagB pgi pgi ppc ppc AFW93721.1 AFW93721.1 glgC glgC glgA glgA glk glk AFW93879.1 AFW93879.1 AFW93939.1 AFW93939.1 anmK anmK deoC deoC gpmI gpmI ackA ackA glmU glmU gnd gnd AFW94631.1 AFW94631.1 pfkA pfkA AFW94710.1 AFW94710.1 ppsA ppsA AFW94807.1 AFW94807.1 glmM glmM tpiA tpiA AFW94928.1 AFW94928.1 eno eno nanE nanE AFW95095.1 AFW95095.1 lipA lipA glmS glmS AFW95219.1 AFW95219.1 lpdA lpdA murQ murQ rpiA rpiA ribP ribP lipB lipB glgB glgB fba fba AFW95440.1 AFW95440.1 AFW95441.1 AFW95441.1 glpX glpX tal tal pyk pyk AFW95505.1 AFW95505.1 pgk pgk AFW95584.1 AFW95584.1 AFW95587.1 AFW95587.1 glcD glcD glpX-2 glpX-2 zwf zwf AFW95737.1 AFW95737.1 gap gap AFW95849.1 AFW95849.1 AFW95871.1 AFW95871.1 lipA-2 lipA-2 malQ malQ AFW96459.1 AFW96459.1 AFW96561.1 AFW96561.1 AFW96599.1 AFW96599.1 pdhA pdhA AFW96638.1 AFW96638.1 AFW96667.1 AFW96667.1 AFW96749.1 AFW96749.1 sfsA sfsA AFW96804.1 AFW96804.1 dacA dacA AFW96905.1 AFW96905.1 AFW96914.1 AFW96914.1 ppdK ppdK tkt tkt nagA nagA pgl pgl
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFW92837.1Glucose-1-phosphate cytidylyltransferase. (258 aa)
eda2-dehydro-3-deoxyphosphogluconate/4-hydroxy-2- oxoglutarate aldolase. (236 aa)
AFW92963.1Glycosyl hydrolase family-13 protein. (487 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa)
AFW93028.1Alpha-glucan phosphorylase. (854 aa)
AFW93210.1Phosphoglucomutase/phosphomannomutase. (480 aa)
AFW93394.1Lipoate protein ligase. (241 aa)
nagBGlucosamine-6-phosphate isomerase. (256 aa)
pgiGlucose-6-phosphate isomerase (PGI); Belongs to the GPI family. (528 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1013 aa)
AFW93721.1Pyruvate kinase; Belongs to the pyruvate kinase family. (589 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (429 aa)
glgAGlycogen/starch synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (485 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (341 aa)
AFW93879.1Transcriptional regulator. (332 aa)
AFW93939.1Phosphoketolase. (793 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (383 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (228 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (532 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)
glmUUDP-N-acetylglucosamine diphosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (451 aa)
gndPhosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa)
AFW94631.1Phosphate acetyltransferase. (364 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (361 aa)
AFW94710.1Pyruvate kinase-like protein; Belongs to the pyruvate kinase family. (502 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (811 aa)
AFW94807.1Carbohydrate kinase. (430 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (478 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa)
AFW94928.1ROK family protein. (295 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (222 aa)
AFW95095.1Hypothetical protein. (91 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (289 aa)
glmSGlutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (625 aa)
AFW95219.1Type I glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
lpdADihydrolipoamide dehydrogenase. (476 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (315 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (236 aa)
ribPRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (338 aa)
lipBLipoyltransferase LipB; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (231 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (763 aa)
fbaFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (357 aa)
AFW95440.1FAD binding domain-containing protein. (428 aa)
AFW95441.1Fe-S binding subunit-containing protein. (449 aa)
glpXFructose-1,6-bisphosphatase GlpX, class II; Belongs to the FBPase class 2 family. (345 aa)
talTransaldolase TalAB; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (333 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
AFW95505.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa)
AFW95584.1Malic enzyme. (463 aa)
AFW95587.1Haloacid dehalogenase-like hydrolase. (223 aa)
glcDGlycolate oxidase subunit GlcD. (489 aa)
glpX-2Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (345 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa)
AFW95737.1Alpha amylase catalytic domain-containing protein. (676 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
AFW95849.1Glycosyl transferase group 1 protein. (411 aa)
AFW95871.1Glycoside hydrolase family 57 protein; Belongs to the glycosyl hydrolase 57 family. (530 aa)
lipA-2Lipoyl synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (298 aa)
malQ4-alpha-glucanotransferase. (502 aa)
AFW96459.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (670 aa)
AFW96561.1Mercuric reductase. (485 aa)
AFW96599.1PEP-utilizing enzyme. (775 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (345 aa)
AFW96638.1HAD-superfamily hydrolase, subfamily IA, variant 1. (244 aa)
AFW96667.1Transaldolase. (212 aa)
AFW96749.1Glycoside hydrolase family 3 protein. (361 aa)
sfsASugar fermentation stimulation protein; Belongs to the SfsA family. (255 aa)
AFW96804.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. (429 aa)
dacAHypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (317 aa)
AFW96905.1Glycosyl transferase group 1. (395 aa)
AFW96914.1Phosphoglucomutase. (475 aa)
ppdKPyruvate phosphate dikinase. (955 aa)
tktTransketolase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase. (383 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (240 aa)
Your Current Organism:
Anabaena sp. 90
NCBI taxonomy Id: 46234
Other names: A. sp. 90, Anabaena circinalis 90, Anabaena sp. strain 90
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