(7 nodes) Insulin receptor substrate binding, and PI3K/AKT activation network (Drosophila pseudoobscura)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA10508	Uncharacterized protein, isoform B. (973 aa)
	DpseGA19056	IRS-type PTB domain-containing protein. (272 aa)
	B5DYR5	Insulin-like growth factor 1 receptor. (2293 aa)
	Q29AY5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1112 aa)
	DpseGA21595	Uncharacterized protein, isoform A. (570 aa)
	DpseGA11287	Uncharacterized protein, isoform B. (1126 aa)
	DpseGA15435	Uncharacterized protein. (515 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5DYR5	DpseGA11287	B5DYR5	Q29GU7	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform B.	0.644
B5DYR5	DpseGA15435	B5DYR5	Q29NX3	Insulin-like growth factor 1 receptor.	Uncharacterized protein.	0.980
B5DYR5	DpseGA19056	B5DYR5	A0A0R3NWK0	Insulin-like growth factor 1 receptor.	IRS-type PTB domain-containing protein.	0.998
B5DYR5	DpseGA21595	B5DYR5	Q29DV4	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform A.	0.891
B5DYR5	Q29AY5	B5DYR5	Q29AY5	Insulin-like growth factor 1 receptor.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.958
DpseGA10508	DpseGA11287	A0A0R3NV00	Q29GU7	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform B.	0.644
DpseGA10508	DpseGA15435	A0A0R3NV00	Q29NX3	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.803
DpseGA10508	DpseGA19056	A0A0R3NV00	A0A0R3NWK0	Uncharacterized protein, isoform B.	IRS-type PTB domain-containing protein.	0.937
DpseGA10508	DpseGA21595	A0A0R3NV00	Q29DV4	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.891
DpseGA10508	Q29AY5	A0A0R3NV00	Q29AY5	Uncharacterized protein, isoform B.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.589
DpseGA11287	B5DYR5	Q29GU7	B5DYR5	Uncharacterized protein, isoform B.	Insulin-like growth factor 1 receptor.	0.644
DpseGA11287	DpseGA10508	Q29GU7	A0A0R3NV00	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform B.	0.644
DpseGA11287	DpseGA15435	Q29GU7	Q29NX3	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.764
DpseGA11287	DpseGA21595	Q29GU7	Q29DV4	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.668
DpseGA11287	Q29AY5	Q29GU7	Q29AY5	Uncharacterized protein, isoform B.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.679
DpseGA15435	B5DYR5	Q29NX3	B5DYR5	Uncharacterized protein.	Insulin-like growth factor 1 receptor.	0.980
DpseGA15435	DpseGA10508	Q29NX3	A0A0R3NV00	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.803
DpseGA15435	DpseGA11287	Q29NX3	Q29GU7	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.764
DpseGA15435	DpseGA19056	Q29NX3	A0A0R3NWK0	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.996
DpseGA15435	Q29AY5	Q29NX3	Q29AY5	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.999