(26 nodes) Clathrin coat, and AP-3 adaptor complex network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0R3NGX8	annotation not available (157 aa)
	A0A0R3NRL3	annotation not available (814 aa)
	DpseGA10691	Uncharacterized protein, isoform F. (1159 aa)
	DpseGA10688	AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1056 aa)
	DpseGA29289	Uncharacterized protein, isoform E. (1078 aa)
	DpseGA21142	Uncharacterized protein, isoform C. (868 aa)
	DpseGA22643	Uncharacterized protein, isoform A. (247 aa)
	DpseGA26124	AP-1 complex subunit gamma. (965 aa)
	DpseGA23562	Uncharacterized protein. (1168 aa)
	DpseGA28117	GED domain-containing protein. (167 aa)
	DpseGA22551	Uncharacterized protein. (88 aa)
	Q28YH4	Uncharacterized protein, isoform A. (619 aa)
	Q28Z17	Epidermal growth factor receptor substrate 15. (1255 aa)
	Q290C3	AP-3 complex subunit sigma. (191 aa)
	Q295J6	AP-1 complex subunit mu. (426 aa)
	Q298T6	Uncharacterized protein. (565 aa)
	Q298U5	AP-2 complex subunit mu-1. (437 aa)
	Q299H7	Uncharacterized protein, isoform A. (572 aa)
	Q29B05	AP-2 complex subunit sigma-1. (142 aa)
	DpseGA10714	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	DpseGA21476	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1584 aa)
	DpseGA15778	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (415 aa)
	DpseGA11682	AP complex subunit beta. (924 aa)
	DpseGA11000	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1165 aa)
	alpha-Adaptin	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity). (939 aa)
	DpseGA19975	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (222 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NGX8	DpseGA10688	A0A0R3NGX8	A0A0R3NZG9	annotation not available	AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.	0.812
A0A0R3NGX8	DpseGA10714	A0A0R3NGX8	Q29CQ9	annotation not available	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.538
A0A0R3NGX8	DpseGA11000	A0A0R3NGX8	Q29J51	annotation not available	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.614
A0A0R3NGX8	DpseGA11682	A0A0R3NGX8	Q29H04	annotation not available	AP complex subunit beta.	0.960
A0A0R3NGX8	DpseGA15778	A0A0R3NGX8	Q29GY7	annotation not available	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.412
A0A0R3NGX8	DpseGA19975	A0A0R3NGX8	Q2M0W4	annotation not available	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.673
A0A0R3NGX8	DpseGA21476	A0A0R3NGX8	Q29CS2	annotation not available	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.613
A0A0R3NGX8	DpseGA22551	A0A0R3NGX8	B5DSP7	annotation not available	Uncharacterized protein.	0.613
A0A0R3NGX8	DpseGA26124	A0A0R3NGX8	B5DN54	annotation not available	AP-1 complex subunit gamma.	0.969
A0A0R3NGX8	DpseGA28117	A0A0R3NGX8	B5DSK9	annotation not available	GED domain-containing protein.	0.495
A0A0R3NGX8	Q290C3	A0A0R3NGX8	Q290C3	annotation not available	AP-3 complex subunit sigma.	0.512
A0A0R3NGX8	Q295J6	A0A0R3NGX8	Q295J6	annotation not available	AP-1 complex subunit mu.	0.972
A0A0R3NGX8	alpha-Adaptin	A0A0R3NGX8	Q29N38	annotation not available	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity).	0.812
A0A0R3NRL3	DpseGA10688	A0A0R3NRL3	A0A0R3NZG9	annotation not available	AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.	0.638
A0A0R3NRL3	DpseGA10691	A0A0R3NRL3	A0A0R3NWD9	annotation not available	Uncharacterized protein, isoform F.	0.850
A0A0R3NRL3	DpseGA11000	A0A0R3NRL3	Q29J51	annotation not available	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.657
A0A0R3NRL3	DpseGA11682	A0A0R3NRL3	Q29H04	annotation not available	AP complex subunit beta.	0.747
A0A0R3NRL3	DpseGA19975	A0A0R3NRL3	Q2M0W4	annotation not available	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.836
A0A0R3NRL3	DpseGA21142	A0A0R3NRL3	A0A0R3P7J1	annotation not available	Uncharacterized protein, isoform C.	0.873
A0A0R3NRL3	DpseGA21476	A0A0R3NRL3	Q29CS2	annotation not available	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.830