(11 nodes) Retromer complex, and SNX17/27/31 network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA20953	Uncharacterized protein, isoform B. (454 aa)
	B5E0I2	Vacuolar protein sorting-associated protein 35. (822 aa)
	Q299S6	TBC1 domain family member 5. (664 aa)
	Q29BS2	Uncharacterized protein. (167 aa)
	DpseGA19839	Sorting nexin; Belongs to the sorting nexin family. (561 aa)
	DpseGA17119	Uncharacterized protein, isoform A. (514 aa)
	DpseGA11437	VWFA domain-containing protein. (1398 aa)
	DpseGA13260	Uncharacterized protein. (522 aa)
	DpseGA18414	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (182 aa)
	DpseGA15459	PX domain-containing protein. (456 aa)
	DpseGA19093	PX domain-containing protein. (483 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5E0I2	DpseGA11437	B5E0I2	Q29IC8	Vacuolar protein sorting-associated protein 35.	VWFA domain-containing protein.	0.983
B5E0I2	DpseGA13260	B5E0I2	Q29JJ9	Vacuolar protein sorting-associated protein 35.	Uncharacterized protein.	0.995
B5E0I2	DpseGA15459	B5E0I2	Q29N71	Vacuolar protein sorting-associated protein 35.	PX domain-containing protein.	0.985
B5E0I2	DpseGA17119	B5E0I2	Q29FS0	Vacuolar protein sorting-associated protein 35.	Uncharacterized protein, isoform A.	0.726
B5E0I2	DpseGA18414	B5E0I2	Q29LH2	Vacuolar protein sorting-associated protein 35.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.998
B5E0I2	DpseGA19093	B5E0I2	Q29ND7	Vacuolar protein sorting-associated protein 35.	PX domain-containing protein.	0.634
B5E0I2	DpseGA19839	B5E0I2	Q29EF9	Vacuolar protein sorting-associated protein 35.	Sorting nexin; Belongs to the sorting nexin family.	0.647
B5E0I2	DpseGA20953	B5E0I2	A0A0R3NYP3	Vacuolar protein sorting-associated protein 35.	Uncharacterized protein, isoform B.	0.704
B5E0I2	Q299S6	B5E0I2	Q299S6	Vacuolar protein sorting-associated protein 35.	TBC1 domain family member 5.	0.880
B5E0I2	Q29BS2	B5E0I2	Q29BS2	Vacuolar protein sorting-associated protein 35.	Uncharacterized protein.	0.991
DpseGA11437	B5E0I2	Q29IC8	B5E0I2	VWFA domain-containing protein.	Vacuolar protein sorting-associated protein 35.	0.983
DpseGA11437	DpseGA15459	Q29IC8	Q29N71	VWFA domain-containing protein.	PX domain-containing protein.	0.914
DpseGA11437	DpseGA17119	Q29IC8	Q29FS0	VWFA domain-containing protein.	Uncharacterized protein, isoform A.	0.820
DpseGA11437	DpseGA18414	Q29IC8	Q29LH2	VWFA domain-containing protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.969
DpseGA11437	DpseGA19093	Q29IC8	Q29ND7	VWFA domain-containing protein.	PX domain-containing protein.	0.573
DpseGA11437	DpseGA20953	Q29IC8	A0A0R3NYP3	VWFA domain-containing protein.	Uncharacterized protein, isoform B.	0.538
DpseGA11437	Q299S6	Q29IC8	Q299S6	VWFA domain-containing protein.	TBC1 domain family member 5.	0.747
DpseGA11437	Q29BS2	Q29IC8	Q29BS2	VWFA domain-containing protein.	Uncharacterized protein.	0.956
DpseGA13260	B5E0I2	Q29JJ9	B5E0I2	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35.	0.995
DpseGA13260	DpseGA15459	Q29JJ9	Q29N71	Uncharacterized protein.	PX domain-containing protein.	0.941