(26 nodes) Mixed, incl. Orange domain, and Negative regulation of Notch signaling pathway network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B5DVG7	Uncharacterized protein. (1419 aa)
	B5DXF7	Uncharacterized protein. (356 aa)
	Q291G5	Uncharacterized protein. (189 aa)
	Q292K4	Hairy and enhancer of split, invertebrate. (450 aa)
	Q292R2	Paired mesoderm homeobox protein 2. (216 aa)
	Q296Y0	Hairy and enhancer of split, invertebrate. (188 aa)
	Q296Y1	Hairy and enhancer of split, invertebrate. (214 aa)
	Q296Y2	Hairy and enhancer of split, invertebrate. (200 aa)
	Q296Y3	Uncharacterized protein. (143 aa)
	Q296Y5	Uncharacterized protein. (236 aa)
	Q296Y6	Hairy and enhancer of split, invertebrate. (219 aa)
	Q296Y7	Uncharacterized protein. (156 aa)
	Q296Y9	Uncharacterized protein. (76 aa)
	Q296Z0	Hairy and enhancer of split, invertebrate. (206 aa)
	Q296Z1	Hairy and enhancer of split, invertebrate. (186 aa)
	Q298Y7	Uncharacterized protein. (416 aa)
	Q29B77	Uncharacterized protein. (803 aa)
	DpseGA17007	BHLH domain-containing protein. (619 aa)
	DpseGA17994	Uncharacterized protein. (561 aa)
	DpseGA16381	Uncharacterized protein. (684 aa)
	DpseGA20508	BHLH domain-containing protein. (412 aa)
	DpseGA11334	Uncharacterized protein. (529 aa)
	DpseGA12616	Uncharacterized protein. (544 aa)
	DpseGA18719	Uncharacterized protein. (157 aa)
	DpseGA15923	Uncharacterized protein. (94 aa)
	DpseGA17423	Uncharacterized protein. (151 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5DXF7	Q296Z1	B5DXF7	Q296Z1	Uncharacterized protein.	Hairy and enhancer of split, invertebrate.	0.448
B5DXF7	Q298Y7	B5DXF7	Q298Y7	Uncharacterized protein.	Uncharacterized protein.	0.923
DpseGA11334	DpseGA17007	Q2LZP1	Q29HB7	Uncharacterized protein.	BHLH domain-containing protein.	0.737
DpseGA12616	DpseGA17994	Q2LZU7	Q29KU8	Uncharacterized protein.	Uncharacterized protein.	0.412
DpseGA12616	DpseGA20508	Q2LZU7	Q2LZH0	Uncharacterized protein.	BHLH domain-containing protein.	0.767
DpseGA12616	Q292R2	Q2LZU7	Q292R2	Uncharacterized protein.	Paired mesoderm homeobox protein 2.	0.452
DpseGA15923	DpseGA17423	Q2M181	Q2M182	Uncharacterized protein.	Uncharacterized protein.	0.463
DpseGA15923	DpseGA18719	Q2M181	Q2M180	Uncharacterized protein.	Uncharacterized protein.	0.820
DpseGA15923	Q296Y0	Q2M181	Q296Y0	Uncharacterized protein.	Hairy and enhancer of split, invertebrate.	0.567
DpseGA15923	Q296Y1	Q2M181	Q296Y1	Uncharacterized protein.	Hairy and enhancer of split, invertebrate.	0.723
DpseGA15923	Q296Y3	Q2M181	Q296Y3	Uncharacterized protein.	Uncharacterized protein.	0.409
DpseGA15923	Q296Y7	Q2M181	Q296Y7	Uncharacterized protein.	Uncharacterized protein.	0.822
DpseGA15923	Q296Z1	Q2M181	Q296Z1	Uncharacterized protein.	Hairy and enhancer of split, invertebrate.	0.449
DpseGA16381	DpseGA17007	Q29LN9	Q29HB7	Uncharacterized protein.	BHLH domain-containing protein.	0.502
DpseGA16381	Q292K4	Q29LN9	Q292K4	Uncharacterized protein.	Hairy and enhancer of split, invertebrate.	0.464
DpseGA17007	DpseGA11334	Q29HB7	Q2LZP1	BHLH domain-containing protein.	Uncharacterized protein.	0.737
DpseGA17007	DpseGA16381	Q29HB7	Q29LN9	BHLH domain-containing protein.	Uncharacterized protein.	0.502
DpseGA17007	DpseGA17994	Q29HB7	Q29KU8	BHLH domain-containing protein.	Uncharacterized protein.	0.683
DpseGA17007	Q292K4	Q29HB7	Q292K4	BHLH domain-containing protein.	Hairy and enhancer of split, invertebrate.	0.574
DpseGA17423	DpseGA15923	Q2M182	Q2M181	Uncharacterized protein.	Uncharacterized protein.	0.463