(48 nodes) G alpha (i) signalling events, and G protein-coupled amine receptor activity network (Drosophila pseudoobscura)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0R3NFS7	Gamma-aminobutyric acid type B receptor. (1255 aa)
	A0A0R3NKA3	Uncharacterized protein, isoform A. (723 aa)
	A0A0R3NL13	Uncharacterized protein, isoform B. (1434 aa)
	A0A0R3NPG2	Guanine nucleotide-binding protein G(o) subunit alpha. (354 aa)
	DpseGA13618	Uncharacterized protein, isoform B. (848 aa)
	DpseGA17617	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	DpseGA23154	Uncharacterized protein, isoform C. (340 aa)
	DpseGA14269	Uncharacterized protein, isoform C; Belongs to the G-protein coupled receptor 1 family. (890 aa)
	DpseGA32854	Uncharacterized protein. (166 aa)
	DpseGA22316	Uncharacterized protein, isoform B. (1350 aa)
	DpseGA17564	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1095 aa)
	DpseGA28588	Uncharacterized protein, isoform B. (399 aa)
	DpseGA23084	Glyco_tran_10_N domain-containing protein. (407 aa)
	DpseGA23907	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (495 aa)
	DpseGA23586	Uncharacterized protein, isoform A. (482 aa)
	B5DVQ9	annotation not available (461 aa)
	B5DX60	Neuropeptide S receptor. (502 aa)
	B5E084	Uncharacterized protein. (67 aa)
	I5AMZ4	Octopamine receptor beta. (642 aa)
	I5AN79	Uncharacterized protein. (731 aa)
	I5ANU3	Uncharacterized protein. (512 aa)
	N6W6W5	Muscarinic acetylcholine receptor M3. (833 aa)
	Q28XE9	Regulator of G-protein signaling. (285 aa)
	Q28YH5	Guanine nucleotide-binding protein G(q) subunit alpha. (396 aa)
	Q290U9	5-hydroxytryptamine receptor 1. (641 aa)
	G-salpha60A	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase; Belongs to the G-alpha family. G(s) subfamily. (382 aa)
	Q294W8	Uncharacterized protein. (676 aa)
	Q294W9	Uncharacterized protein, isoform A. (635 aa)
	Q296R1	5-hydroxytryptamine receptor 2. (944 aa)
	Q297N2	5-hydroxytryptamine receptor 2. (971 aa)
	Q29A17	Uncharacterized protein, isoform A. (614 aa)
	Q29A18	Uncharacterized protein, isoform A. (633 aa)
	Q29AS6	Muscarinic acetylcholine receptor M3. (1140 aa)
	Q29BJ2	Allatostatin A receptor. (357 aa)
	Q29BV5	Dopamine receptor D1-like. (846 aa)
	DpseGA21307	WD_REPEATS_REGION domain-containing protein. (346 aa)
	DpseGA20386	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (625 aa)
	DpseGA10039	Uncharacterized protein. (355 aa)
	DpseGA21548	Uncharacterized protein, isoform A. (638 aa)
	DpseGA17628	Uncharacterized protein. (443 aa)
	DpseGA15495	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	DpseGA10552	WD_REPEATS_REGION domain-containing protein. (356 aa)
	DpseGA11816	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (502 aa)
	DpseGA21615	Uncharacterized protein, isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1735 aa)
	DpseGA15728	G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family. (1369 aa)
	DpseGA18269	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1301 aa)
	DpseGA12470	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (564 aa)
	DpseGA20503	Phosducin domain-containing protein. (276 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NFS7	A0A0R3NL13	A0A0R3NFS7	A0A0R3NL13	Gamma-aminobutyric acid type B receptor.	Uncharacterized protein, isoform B.	0.518
A0A0R3NFS7	B5E084	A0A0R3NFS7	B5E084	Gamma-aminobutyric acid type B receptor.	Uncharacterized protein.	0.499
A0A0R3NFS7	DpseGA10552	A0A0R3NFS7	Q29HD3	Gamma-aminobutyric acid type B receptor.	WD_REPEATS_REGION domain-containing protein.	0.480
A0A0R3NFS7	DpseGA13618	A0A0R3NFS7	A0A0R3NQZ1	Gamma-aminobutyric acid type B receptor.	Uncharacterized protein, isoform B.	0.990
A0A0R3NFS7	DpseGA15728	A0A0R3NFS7	Q29LM3	Gamma-aminobutyric acid type B receptor.	G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family.	0.907
A0A0R3NFS7	DpseGA17617	A0A0R3NFS7	A0A0R3NVC3	Gamma-aminobutyric acid type B receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.442
A0A0R3NFS7	DpseGA21307	A0A0R3NFS7	Q29DE4	Gamma-aminobutyric acid type B receptor.	WD_REPEATS_REGION domain-containing protein.	0.402
A0A0R3NFS7	DpseGA23154	A0A0R3NFS7	A0A0R3NW55	Gamma-aminobutyric acid type B receptor.	Uncharacterized protein, isoform C.	0.480
A0A0R3NFS7	DpseGA32854	A0A0R3NFS7	A0A0R3P1I2	Gamma-aminobutyric acid type B receptor.	Uncharacterized protein.	0.442
A0A0R3NKA3	B5E084	A0A0R3NKA3	B5E084	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.755
A0A0R3NKA3	DpseGA10552	A0A0R3NKA3	Q29HD3	Uncharacterized protein, isoform A.	WD_REPEATS_REGION domain-containing protein.	0.804
A0A0R3NKA3	DpseGA17564	A0A0R3NKA3	A0A0R3P326	Uncharacterized protein, isoform A.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.486
A0A0R3NKA3	DpseGA17617	A0A0R3NKA3	A0A0R3NVC3	Uncharacterized protein, isoform A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.755
A0A0R3NKA3	DpseGA18269	A0A0R3NKA3	Q29N33	Uncharacterized protein, isoform A.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.495
A0A0R3NKA3	DpseGA21307	A0A0R3NKA3	Q29DE4	Uncharacterized protein, isoform A.	WD_REPEATS_REGION domain-containing protein.	0.804
A0A0R3NKA3	DpseGA21548	A0A0R3NKA3	Q29FK8	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.654
A0A0R3NKA3	DpseGA21615	A0A0R3NKA3	Q29JG3	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.525
A0A0R3NKA3	DpseGA22316	A0A0R3NKA3	A0A0R3P1S1	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.654
A0A0R3NKA3	DpseGA23084	A0A0R3NKA3	B5DLM8	Uncharacterized protein, isoform A.	Glyco_tran_10_N domain-containing protein.	0.906
A0A0R3NKA3	DpseGA23154	A0A0R3NKA3	A0A0R3NW55	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform C.	0.804