11 items (Drosophila pseudoobscura) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	A0A0R3NLS2	Uncharacterized protein. (441 aa)
	B5E0E9	Uncharacterized protein. (181 aa)
	fl(2)d	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...] (560 aa)
	Q290Y6	Uncharacterized protein. (803 aa)
	GA20428	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA). Belongs to the methyltransferase superfamily. METTL16/RlmF family. (305 aa)
	vir	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...] (1849 aa)
	Q298L6	MRNA m6A methyltransferase catalytic subunit. (612 aa)
	DpseGA21950	MTS domain-containing protein. (214 aa)
	DpseGA20292	Uncharacterized protein. (1249 aa)
	DpseGA20607	Uncharacterized protein; Belongs to the MT-A70-like family. (445 aa)
	DpseGA10202	RING-type domain-containing protein. (433 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NLS2	DpseGA20292	A0A0R3NLS2	Q29GD6	Uncharacterized protein.	Uncharacterized protein.	0.601
A0A0R3NLS2	DpseGA20607	A0A0R3NLS2	Q29MN2	Uncharacterized protein.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.672
A0A0R3NLS2	DpseGA21950	A0A0R3NLS2	Q29DH6	Uncharacterized protein.	MTS domain-containing protein.	0.664
A0A0R3NLS2	GA20428	A0A0R3NLS2	Q290Z2	Uncharacterized protein.	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA). Belongs to the methyltransferase superfamily. METTL16/RlmF family.	0.644
A0A0R3NLS2	Q290Y6	A0A0R3NLS2	Q290Y6	Uncharacterized protein.	Uncharacterized protein.	0.416
A0A0R3NLS2	Q298L6	A0A0R3NLS2	Q298L6	Uncharacterized protein.	MRNA m6A methyltransferase catalytic subunit.	0.466
A0A0R3NLS2	fl(2)d	A0A0R3NLS2	Q28XY0	Uncharacterized protein.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.541
A0A0R3NLS2	vir	A0A0R3NLS2	Q291E4	Uncharacterized protein.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.541
B5E0E9	DpseGA10202	B5E0E9	Q29PG8	Uncharacterized protein.	RING-type domain-containing protein.	0.524
B5E0E9	DpseGA20607	B5E0E9	Q29MN2	Uncharacterized protein.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.966
B5E0E9	GA20428	B5E0E9	Q290Z2	Uncharacterized protein.	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA). Belongs to the methyltransferase superfamily. METTL16/RlmF family.	0.531
B5E0E9	Q290Y6	B5E0E9	Q290Y6	Uncharacterized protein.	Uncharacterized protein.	0.480
B5E0E9	fl(2)d	B5E0E9	Q28XY0	Uncharacterized protein.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.942
B5E0E9	vir	B5E0E9	Q291E4	Uncharacterized protein.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.633
DpseGA10202	B5E0E9	Q29PG8	B5E0E9	RING-type domain-containing protein.	Uncharacterized protein.	0.524
DpseGA10202	DpseGA20292	Q29PG8	Q29GD6	RING-type domain-containing protein.	Uncharacterized protein.	0.694
DpseGA10202	DpseGA20607	Q29PG8	Q29MN2	RING-type domain-containing protein.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.680
DpseGA10202	GA20428	Q29PG8	Q290Z2	RING-type domain-containing protein.	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA). Belongs to the methyltransferase superfamily. METTL16/RlmF family.	0.605
DpseGA10202	Q290Y6	Q29PG8	Q290Y6	RING-type domain-containing protein.	Uncharacterized protein.	0.597
DpseGA10202	Q298L6	Q29PG8	Q298L6	RING-type domain-containing protein.	MRNA m6A methyltransferase catalytic subunit.	0.677