6 items (Drosophila pseudoobscura) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fl(2)d	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...] (560 aa)
	vir	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...] (1849 aa)
	Q298L6	MRNA m6A methyltransferase catalytic subunit. (612 aa)
	DpseGA20292	Uncharacterized protein. (1249 aa)
	DpseGA20607	Uncharacterized protein; Belongs to the MT-A70-like family. (445 aa)
	DpseGA10202	RING-type domain-containing protein. (433 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DpseGA10202	DpseGA20292	Q29PG8	Q29GD6	RING-type domain-containing protein.	Uncharacterized protein.	0.694
DpseGA10202	DpseGA20607	Q29PG8	Q29MN2	RING-type domain-containing protein.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.680
DpseGA10202	Q298L6	Q29PG8	Q298L6	RING-type domain-containing protein.	MRNA m6A methyltransferase catalytic subunit.	0.677
DpseGA10202	fl(2)d	Q29PG8	Q28XY0	RING-type domain-containing protein.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.956
DpseGA10202	vir	Q29PG8	Q291E4	RING-type domain-containing protein.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.931
DpseGA20292	DpseGA10202	Q29GD6	Q29PG8	Uncharacterized protein.	RING-type domain-containing protein.	0.694
DpseGA20292	DpseGA20607	Q29GD6	Q29MN2	Uncharacterized protein.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.803
DpseGA20292	Q298L6	Q29GD6	Q298L6	Uncharacterized protein.	MRNA m6A methyltransferase catalytic subunit.	0.694
DpseGA20292	fl(2)d	Q29GD6	Q28XY0	Uncharacterized protein.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.996
DpseGA20292	vir	Q29GD6	Q291E4	Uncharacterized protein.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.986
DpseGA20607	DpseGA10202	Q29MN2	Q29PG8	Uncharacterized protein; Belongs to the MT-A70-like family.	RING-type domain-containing protein.	0.680
DpseGA20607	DpseGA20292	Q29MN2	Q29GD6	Uncharacterized protein; Belongs to the MT-A70-like family.	Uncharacterized protein.	0.803
DpseGA20607	Q298L6	Q29MN2	Q298L6	Uncharacterized protein; Belongs to the MT-A70-like family.	MRNA m6A methyltransferase catalytic subunit.	0.996
DpseGA20607	fl(2)d	Q29MN2	Q28XY0	Uncharacterized protein; Belongs to the MT-A70-like family.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.976
DpseGA20607	vir	Q29MN2	Q291E4	Uncharacterized protein; Belongs to the MT-A70-like family.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.817
Q298L6	DpseGA10202	Q298L6	Q29PG8	MRNA m6A methyltransferase catalytic subunit.	RING-type domain-containing protein.	0.677
Q298L6	DpseGA20292	Q298L6	Q29GD6	MRNA m6A methyltransferase catalytic subunit.	Uncharacterized protein.	0.694
Q298L6	DpseGA20607	Q298L6	Q29MN2	MRNA m6A methyltransferase catalytic subunit.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.996
Q298L6	fl(2)d	Q298L6	Q28XY0	MRNA m6A methyltransferase catalytic subunit.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.979
Q298L6	vir	Q298L6	Q291E4	MRNA m6A methyltransferase catalytic subunit.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.780