(82 nodes) Motor neuron axon guidance network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q28X54	Uncharacterized protein, isoform B. (1098 aa)
	Q28XN3	Uncharacterized protein, isoform F. (436 aa)
	Q28XS1	Uncharacterized protein, isoform A. (1058 aa)
	Dpse_eve	Homeobox even-skipped homolog protein. (359 aa)
	Q28ZX6	PDZ domain-containing protein GIPC. (343 aa)
	Q290U3	Cyclin-dependent kinase 5. (294 aa)
	Q291P5	Roundabout, axon guidance receptor 2. (1398 aa)
	Q295B9	Uncharacterized protein, isoform A. (517 aa)
	Q295V0	Extracellular sulfatase Sulf. (1156 aa)
	Q299A5	Uncharacterized protein. (712 aa)
	Q299P2	Uncharacterized protein, isoform A. (302 aa)
	Q299P4	Uncharacterized protein. (299 aa)
	Q299P6	Uncharacterized protein, isoform D. (357 aa)
	Q299Y4	Uncharacterized protein. (323 aa)
	Q29A71	Uncharacterized protein. (472 aa)
	DpseGA15321	Uncharacterized protein. (192 aa)
	DpseGA14061	Uncharacterized protein, isoform A. (1309 aa)
	DpseGA11746	Uncharacterized protein. (314 aa)
	DpseGA14904	Uncharacterized protein. (618 aa)
	Cdc42	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity). (191 aa)
	DpseGA14821	Uncharacterized protein. (2048 aa)
	DpseGA17047	Uncharacterized protein. (2886 aa)
	Sema-1a	Sema-1a, isoform D; Belongs to the semaphorin family. (854 aa)
	DpseGA10505	Uncharacterized protein. (525 aa)
	DpseGA20502	Ig-like domain-containing protein. (351 aa)
	DpseGA13521	Uncharacterized protein, isoform A. (393 aa)
	DpseGA11722	Uncharacterized protein, isoform A. (359 aa)
	DpseGA18959	Uncharacterized protein, isoform A. (236 aa)
	DpseGA10020	Uncharacterized protein, isoform C. (1146 aa)
	DpseGA10441	Uncharacterized protein. (548 aa)
	DpseGA20256	Uncharacterized protein. (682 aa)
	DpseGA10887	LRRCT domain-containing protein. (772 aa)
	DpseGA10681	Uncharacterized protein. (1460 aa)
	Q29AD5	Uncharacterized protein, isoform O. (403 aa)
	DpseGA16783	Uncharacterized protein. (452 aa)
	DpseGA22158	Uncharacterized protein, isoform A. (395 aa)
	DpseGA10404	Stork_head domain-containing protein. (1133 aa)
	DpseGA21968	PID domain-containing protein. (2530 aa)
	A0A0R3NJF4	Uncharacterized protein, isoform A. (2563 aa)
	A0A0R3NLJ2	Uncharacterized protein, isoform B. (1081 aa)
	A0A0R3NM99	Uncharacterized protein, isoform D. (649 aa)
	DpseGA25881	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (543 aa)
	A0A0R3NSV9	Uncharacterized protein, isoform A. (1515 aa)
	DpseGA18474	Uncharacterized protein, isoform C. (426 aa)
	DpseGA28096	Uncharacterized protein, isoform B. (2051 aa)
	DpseGA31138	Uncharacterized protein. (456 aa)
	DpseGA12925	Uncharacterized protein, isoform B. (984 aa)
	DpseGA19940	Uncharacterized protein, isoform B. (1664 aa)
	DpseGA17599	Uncharacterized protein, isoform D. (891 aa)
	DpseGA23588	Uncharacterized protein, isoform E. (1058 aa)
	DpseGA19916	Uncharacterized protein, isoform B. (968 aa)
	DpseGA28649	Uncharacterized protein. (178 aa)
	DpseGA28200	Uncharacterized protein, isoform C. (165 aa)
	DpseGA11663	Uncharacterized protein, isoform L. (4858 aa)
	DpseGA25171	Uncharacterized protein. (2525 aa)
	DpseGA29045	Uncharacterized protein, isoform A. (580 aa)
	DpseGA28035	COesterase domain-containing protein. (998 aa)
	DpseGA28082	Uncharacterized protein. (773 aa)
	DpseGA28528	Uncharacterized protein. (2709 aa)
	DpseGA29267	Uncharacterized protein. (808 aa)
	DpseGA29271	Uncharacterized protein, isoform B. (353 aa)
	DpseGA23763	LRRCT domain-containing protein. (831 aa)
	DpseGA23612	Uncharacterized protein. (192 aa)
	DpseGA28220	Guanylate cyclase. (1534 aa)
	DpseGA23302	Uncharacterized protein. (407 aa)
	B5DX46	Uncharacterized protein. (437 aa)
	B5DYG0	Uncharacterized protein. (787 aa)
	B5DZ84	Uncharacterized protein, isoform A. (205 aa)
	B5E0D1	Uncharacterized protein, isoform C. (713 aa)
	B5E0Y5	Uncharacterized protein. (701 aa)
	I5AMY8	Receptor-type tyrosine-protein phosphatase gamma. (1469 aa)
	DpseGA18843	Uncharacterized protein. (132 aa)
	DpseGA14409	Sema domain-containing protein. (2071 aa)
	Q29CB6	Zinc finger homeobox protein 2. (1336 aa)
	Q29BZ7	Uncharacterized protein, isoform B. (1463 aa)
	Q29BP9	Uncharacterized protein, isoform A. (444 aa)
	DpseGA10024	POU domain protein. (755 aa)
	DpseGA21999	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (818 aa)
	DpseGA21682	NUC205 domain-containing protein. (674 aa)
	DpseGA20417	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
	DpseGA17894	Uncharacterized protein. (1860 aa)
	DpseGA18565	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (527 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NJF4	Cdc42	A0A0R3NJF4	Q29HY3	Uncharacterized protein, isoform A.	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	0.510
A0A0R3NJF4	DpseGA15321	A0A0R3NJF4	Q29EV6	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.420
A0A0R3NJF4	DpseGA23612	A0A0R3NJF4	B5DQJ0	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.420
A0A0R3NLJ2	Q299Y4	A0A0R3NLJ2	Q299Y4	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.455
A0A0R3NM99	DpseGA21999	A0A0R3NM99	Q29DI2	Uncharacterized protein, isoform D.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.914
A0A0R3NM99	DpseGA25881	A0A0R3NM99	A0A0R3NRN4	Uncharacterized protein, isoform D.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.478
A0A0R3NSV9	DpseGA14409	A0A0R3NSV9	Q29CL9	Uncharacterized protein, isoform A.	Sema domain-containing protein.	0.472
B5DZ84	Cdc42	B5DZ84	Q29HY3	Uncharacterized protein, isoform A.	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	0.749
B5DZ84	DpseGA14409	B5DZ84	Q29CL9	Uncharacterized protein, isoform A.	Sema domain-containing protein.	0.731
B5DZ84	DpseGA14904	B5DZ84	Q29H20	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.736
B5DZ84	DpseGA15321	B5DZ84	Q29EV6	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.794
B5DZ84	DpseGA17894	B5DZ84	Q29D50	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.471
B5DZ84	DpseGA23612	B5DZ84	B5DQJ0	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.749
B5DZ84	Q290U3	B5DZ84	Q290U3	Uncharacterized protein, isoform A.	Cyclin-dependent kinase 5.	0.424
B5DZ84	Sema-1a	B5DZ84	Q29JT4	Uncharacterized protein, isoform A.	Sema-1a, isoform D; Belongs to the semaphorin family.	0.428
Cdc42	A0A0R3NJF4	Q29HY3	A0A0R3NJF4	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	Uncharacterized protein, isoform A.	0.510
Cdc42	B5DZ84	Q29HY3	B5DZ84	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	Uncharacterized protein, isoform A.	0.749
Cdc42	DpseGA14409	Q29HY3	Q29CL9	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	Sema domain-containing protein.	0.520
Cdc42	DpseGA14904	Q29HY3	Q29H20	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	Uncharacterized protein.	0.603
Cdc42	DpseGA17894	Q29HY3	Q29D50	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	Uncharacterized protein.	0.524