(82 nodes) Cell growth network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q297H8	Mothers against decapentaplegic homolog 6. (584 aa)
	jagn	Protein jagunal; Required for endoplasmic reticulum organization and proper vesicular traffic during vitellogenesis. Required for oocyte and bristle growth; Belongs to the jagunal family. (197 aa)
	Q29BH0	Ras-related C3 botulinum toxin substrate 1. (195 aa)
	Q29BL5	Uncharacterized protein, isoform A. (1334 aa)
	DpseGA19569	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (612 aa)
	DpseGA21324	Mitogen-activated protein kinase kinase kinase. (994 aa)
	DpseGA21999	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (818 aa)
	DpseGA17443	Uncharacterized protein, isoform A. (469 aa)
	DpseGA11530	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (976 aa)
	DpseGA15321	Uncharacterized protein. (192 aa)
	DpseGA14061	Uncharacterized protein, isoform A. (1309 aa)
	DpseGA15227	Uncharacterized protein. (656 aa)
	DpseGA17546	Uncharacterized protein, isoform A. (174 aa)
	DpseGA14904	Uncharacterized protein. (618 aa)
	Cdc42	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity). (191 aa)
	DpseGA13122	Uncharacterized protein. (1496 aa)
	poe	Protein purity of essence; Has a role in growth of the perineurial glial layer of the larval peripheral nerve. May have a role in male fertility and eye development or function. May bind calmodulin (By similarity). (5381 aa)
	DpseGA13735	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (886 aa)
	DpseGA20415	Uncharacterized protein, isoform B; Cadherins are calcium-dependent cell adhesion proteins. (1800 aa)
	DpseGA12709	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DpseGA17598	Uncharacterized protein, isoform A. (218 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	DpseGA18145	Uncharacterized protein, isoform C; Belongs to the protein kinase superfamily. (353 aa)
	DpseGA10833	Uncharacterized protein. (1210 aa)
	DpseGA20087	RING-type domain-containing protein. (285 aa)
	DpseGA10675	Protein kinase domain-containing protein. (859 aa)
	DpseGA14615	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (619 aa)
	DpseGA20642	RING-type domain-containing protein. (299 aa)
	DpseGA21612	CAP-Gly domain-containing protein. (1262 aa)
	Q28YP3	Chromatin licensing and DNA replication factor 1. (730 aa)
	Dpse_Dscam	Dscam, isoform B. (2049 aa)
	DpseGA14181	Uncharacterized protein, isoform B. (718 aa)
	A0A0R3NTR6	Rho guanine nucleotide exchange factor 12. (2671 aa)
	DpseGA26093	Uncharacterized protein, isoform J; Cadherins are calcium-dependent cell adhesion proteins. (3120 aa)
	DpseGA28096	Uncharacterized protein, isoform B. (2051 aa)
	DpseGA18320	Uncharacterized protein, isoform C. (678 aa)
	DpseGA14074	Uncharacterized protein, isoform B. (1736 aa)
	DpseGA19056	IRS-type PTB domain-containing protein. (272 aa)
	DpseGA31562	Uncharacterized protein. (235 aa)
	DpseGA25944	Uncharacterized protein. (186 aa)
	DpseGA26435	Uncharacterized protein, isoform C. (1782 aa)
	DpseGA14746	Uncharacterized protein, isoform D. (1364 aa)
	DpseGA31031	Uncharacterized protein. (1892 aa)
	DpseGA23604	Uncharacterized protein. (4564 aa)
	DpseGA23028	Uncharacterized protein, isoform N. (1304 aa)
	DpseGA30601	Uncharacterized protein. (113 aa)
	DpseGA29217	Uncharacterized protein, isoform B; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (2304 aa)
	DpseGA26555	Uncharacterized protein, isoform C; Belongs to the potassium channel family. (764 aa)
	DpseGA11051	Uncharacterized protein, isoform B. (929 aa)
	DpseGA16706	Uncharacterized protein, isoform E. (1186 aa)
	A0A158SUH8	Uncharacterized protein. (164 aa)
	DpseGA22607	Uncharacterized protein, isoform A. (1248 aa)
	DpseGA23083	Uncharacterized protein. (365 aa)
	DpseGA28549	Uncharacterized protein. (585 aa)
	DpseGA28799	Uncharacterized protein, isoform B. (134 aa)
	DpseGA26564	Ion_trans domain-containing protein; Belongs to the potassium channel family. (171 aa)
	DpseGA23504	Uncharacterized protein. (264 aa)
	DpseGA23612	Uncharacterized protein. (192 aa)
	DpseGA28349	Uncharacterized protein. (146 aa)
	B5DX59	Uncharacterized protein. (2795 aa)
	B5DX82	Uncharacterized protein, isoform B. (800 aa)
	B5DYR5	Insulin-like growth factor 1 receptor. (2293 aa)
	B5DZ84	Uncharacterized protein, isoform A. (205 aa)
	B5E0S0	Uncharacterized protein, isoform A. (288 aa)
	B5E1G4	Uncharacterized protein, isoform A. (1517 aa)
	DpseGA18272	Nucleoporin_N domain-containing protein. (586 aa)
	Dpse_vg	Vg. (439 aa)
	A0A0R3NPB8	Uncharacterized protein. (147 aa)
	Q28YQ6	Uncharacterized protein, isoform A. (1318 aa)
	Q28ZT5	Low density lipoprotein receptor-related protein 5/6. (1687 aa)
	Q291J2	Uncharacterized protein, isoform A. (938 aa)
	Q291M3	Uncharacterized protein. (1819 aa)
	Q293D2	Uncharacterized protein, isoform C. (1127 aa)
	Q293G6	Uncharacterized protein. (663 aa)
	Q293W0	Uncharacterized protein, isoform A. (800 aa)
	Q295H5	Uncharacterized protein. (529 aa)
	Q296V6	Ras-related protein Rab-11A. (214 aa)
	A0A0R3NGF8	Uncharacterized protein. (142 aa)
	A0A0R3NH46	Uncharacterized protein, isoform A. (478 aa)
	A0A0R3NHX1	Rho GTPase-activating protein SYDE. (1882 aa)
	A0A0R3NNC1	Uncharacterized protein, isoform A. (263 aa)
	A0A0R3NPB6	Wingless-type MMTV integration site family, member 7. (384 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NGF8	DpseGA14615	A0A0R3NGF8	Q2LZT5	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.418
A0A0R3NGF8	DpseGA14904	A0A0R3NGF8	Q29H20	Uncharacterized protein.	Uncharacterized protein.	0.520
A0A0R3NH46	B5DZ84	A0A0R3NH46	B5DZ84	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.504
A0A0R3NH46	Cdc42	A0A0R3NH46	Q29HY3	Uncharacterized protein, isoform A.	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	0.605
A0A0R3NH46	DpseGA15321	A0A0R3NH46	Q29EV6	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.605
A0A0R3NH46	DpseGA18320	A0A0R3NH46	A0A0R3NVX7	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform C.	0.982
A0A0R3NH46	DpseGA23612	A0A0R3NH46	B5DQJ0	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.605
A0A0R3NH46	Q29BH0	A0A0R3NH46	Q29BH0	Uncharacterized protein, isoform A.	Ras-related C3 botulinum toxin substrate 1.	0.605
A0A0R3NHX1	B5DZ84	A0A0R3NHX1	B5DZ84	Rho GTPase-activating protein SYDE.	Uncharacterized protein, isoform A.	0.637
A0A0R3NHX1	DpseGA10833	A0A0R3NHX1	Q29P18	Rho GTPase-activating protein SYDE.	Uncharacterized protein.	0.474
A0A0R3NNC1	DpseGA14615	A0A0R3NNC1	Q2LZT5	Uncharacterized protein, isoform A.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.418
A0A0R3NNC1	DpseGA14904	A0A0R3NNC1	Q29H20	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.520
A0A0R3NPB6	DpseGA14615	A0A0R3NPB6	Q2LZT5	Wingless-type MMTV integration site family, member 7.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.936
A0A0R3NPB6	DpseGA14904	A0A0R3NPB6	Q29H20	Wingless-type MMTV integration site family, member 7.	Uncharacterized protein.	0.659
A0A0R3NPB6	DpseGA21999	A0A0R3NPB6	Q29DI2	Wingless-type MMTV integration site family, member 7.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.871
A0A0R3NPB6	Q28ZT5	A0A0R3NPB6	Q28ZT5	Wingless-type MMTV integration site family, member 7.	Low density lipoprotein receptor-related protein 5/6.	0.934
A0A0R3NPB8	DpseGA14615	A0A0R3NPB8	Q2LZT5	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.418
A0A0R3NPB8	DpseGA14904	A0A0R3NPB8	Q29H20	Uncharacterized protein.	Uncharacterized protein.	0.520
A0A0R3NTR6	B5DZ84	A0A0R3NTR6	B5DZ84	Rho guanine nucleotide exchange factor 12.	Uncharacterized protein, isoform A.	0.968
A0A0R3NTR6	Cdc42	A0A0R3NTR6	Q29HY3	Rho guanine nucleotide exchange factor 12.	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	0.709