(12 nodes) Tumor necrosis factor-mediated signaling pathway network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q28WN5	Uncharacterized protein, isoform A. (857 aa)
	Q297N4	Mitogen-activated protein kinase kinase 4. (428 aa)
	DpseGA14958	Protein kinase domain-containing protein. (683 aa)
	DpseGA10670	Uncharacterized protein. (464 aa)
	DpseGA11504	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
	DpseGA10133	Uncharacterized protein, isoform B. (242 aa)
	DpseGA18154	Uncharacterized protein, isoform B. (484 aa)
	DpseGA22607	Uncharacterized protein, isoform A. (1248 aa)
	DpseGA24328	Uncharacterized protein. (1561 aa)
	DpseGA27758	Uncharacterized protein. (371 aa)
	B5DXC1	Disintegrin and metalloproteinase domain-containing protein 17. (743 aa)
	B5E1J5	Uncharacterized protein, isoform A. (424 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5E1J5	DpseGA10133	B5E1J5	A0A0R3NY52	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.891
B5E1J5	DpseGA14958	B5E1J5	Q29GL6	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein.	0.761
B5E1J5	DpseGA27758	B5E1J5	B5DVE3	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.967
DpseGA10133	B5E1J5	A0A0R3NY52	B5E1J5	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.891
DpseGA10133	DpseGA27758	A0A0R3NY52	B5DVE3	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.403
DpseGA10670	DpseGA11504	Q29HD1	Q29IB7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.675
DpseGA10670	DpseGA14958	Q29HD1	Q29GL6	Uncharacterized protein.	Protein kinase domain-containing protein.	0.991
DpseGA10670	DpseGA18154	Q29HD1	A0A0R3P705	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.960
DpseGA10670	DpseGA22607	Q29HD1	B5DLK8	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.454
DpseGA10670	DpseGA24328	Q29HD1	B5DP66	Uncharacterized protein.	Uncharacterized protein.	0.911
DpseGA10670	DpseGA27758	Q29HD1	B5DVE3	Uncharacterized protein.	Uncharacterized protein.	0.946
DpseGA10670	Q28WN5	Q29HD1	Q28WN5	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.997
DpseGA10670	Q297N4	Q29HD1	Q297N4	Uncharacterized protein.	Mitogen-activated protein kinase kinase 4.	0.609
DpseGA11504	DpseGA10670	Q29IB7	Q29HD1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.675
DpseGA11504	DpseGA14958	Q29IB7	Q29GL6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.972
DpseGA11504	DpseGA18154	Q29IB7	A0A0R3P705	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein, isoform B.	0.422
DpseGA11504	Q28WN5	Q29IB7	Q28WN5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein, isoform A.	0.557
DpseGA14958	B5E1J5	Q29GL6	B5E1J5	Protein kinase domain-containing protein.	Uncharacterized protein, isoform A.	0.761
DpseGA14958	DpseGA10670	Q29GL6	Q29HD1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.991
DpseGA14958	DpseGA11504	Q29GL6	Q29IB7	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.972