(38 nodes) Regulation of hemocyte proliferation network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA19867	Uncharacterized protein, isoform E. (1051 aa)
	Q28Z81	Uncharacterized protein. (504 aa)
	DpseGA19765	Uncharacterized protein, isoform B. (981 aa)
	Q290K1	Classical protein kinase C alpha type. (683 aa)
	Q292H9	Uncharacterized protein. (192 aa)
	Q293I7	Uncharacterized protein. (661 aa)
	Q294V1	RAC serine/threonine-protein kinase. (530 aa)
	Q295K4	Uncharacterized protein, isoform A. (835 aa)
	Q295T4	Uncharacterized protein, isoform E. (892 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	Q296C9	COP9 signalosome complex subunit 5. (327 aa)
	Dpse_Tl	Protein toll. (1120 aa)
	DpseGA28588	Uncharacterized protein, isoform B. (399 aa)
	DpseGA26902	UBIQUITIN_CONJUGAT_2 domain-containing protein. (178 aa)
	DpseGA23814	Uncharacterized protein. (213 aa)
	B5DWF5	RNA polymerase-associated protein LEO1. (719 aa)
	B5E1A1	Nucleosome-remodeling factor 38 kDa subunit. (336 aa)
	B5E1M6	Uncharacterized protein, isoform A. (899 aa)
	Q28WQ2	Superoxide dismutase, Fe-Mn family. (244 aa)
	Dpse_EcR	Ecdysone receptor. (700 aa)
	GA18610	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (786 aa)
	Q28YH3	Paired amphipathic helix protein Sin3a. (2143 aa)
	DpseGA19047	Uncharacterized protein, isoform C. (503 aa)
	DpseGA29036	Uncharacterized protein, isoform B. (543 aa)
	DpseGA21999	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (818 aa)
	DpseGA20722	Uncharacterized protein. (213 aa)
	DpseGA14036	Uncharacterized protein. (1178 aa)
	DpseGA23102	Uncharacterized protein, isoform E. (162 aa)
	DpseGA15704	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	DpseGA19197	Uncharacterized protein. (354 aa)
	DpseGA21482	Uncharacterized protein. (691 aa)
	DpseGA14615	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (619 aa)
	DpseGA19920	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (506 aa)
	DpseGA21222	MRG domain-containing protein. (513 aa)
	A0A0R3NK64	Uncharacterized protein. (553 aa)
	A0A0R3NNU9	Uncharacterized protein, isoform B. (3305 aa)
	A0A0R3NP25	Uncharacterized protein, isoform A. (5154 aa)
	DpseGA25881	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (543 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NNU9	DpseGA21222	A0A0R3NNU9	Q2M0T3	Uncharacterized protein, isoform B.	MRG domain-containing protein.	0.572
A0A0R3NNU9	Q28YH3	A0A0R3NNU9	Q28YH3	Uncharacterized protein, isoform B.	Paired amphipathic helix protein Sin3a.	0.491
A0A0R3NNU9	Q296C9	A0A0R3NNU9	Q296C9	Uncharacterized protein, isoform B.	COP9 signalosome complex subunit 5.	0.447
B5E1A1	Q28WQ2	B5E1A1	Q28WQ2	Nucleosome-remodeling factor 38 kDa subunit.	Superoxide dismutase, Fe-Mn family.	0.714
B5E1M6	Dpse_EcR	B5E1M6	Q28WY6	Uncharacterized protein, isoform A.	Ecdysone receptor.	0.900
DpseGA14036	DpseGA19047	Q29H22	A0A0R3NW51	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.535
DpseGA14036	Q294V1	Q29H22	Q294V1	Uncharacterized protein.	RAC serine/threonine-protein kinase.	0.513
DpseGA14036	Ras85D	Q29H22	Q295X7	Uncharacterized protein.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.486
DpseGA14615	DpseGA25881	Q2LZT5	A0A0R3NRN4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.904
DpseGA15704	DpseGA19765	Q29N51	A0A0R3NS75	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein, isoform B.	0.457
DpseGA15704	DpseGA19867	Q29N51	A0A0R3NSZ5	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein, isoform E.	0.426
DpseGA15704	DpseGA26902	Q29N51	B5DMF4	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.906
DpseGA15704	Q28YH3	Q29N51	Q28YH3	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Paired amphipathic helix protein Sin3a.	0.430
DpseGA19047	DpseGA14036	A0A0R3NW51	Q29H22	Uncharacterized protein, isoform C.	Uncharacterized protein.	0.535
DpseGA19047	Q294V1	A0A0R3NW51	Q294V1	Uncharacterized protein, isoform C.	RAC serine/threonine-protein kinase.	0.903
DpseGA19047	Q295K4	A0A0R3NW51	Q295K4	Uncharacterized protein, isoform C.	Uncharacterized protein, isoform A.	0.473
DpseGA19765	DpseGA15704	A0A0R3NS75	Q29N51	Uncharacterized protein, isoform B.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.457
DpseGA19765	DpseGA19867	A0A0R3NS75	A0A0R3NSZ5	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform E.	0.953
DpseGA19765	Q28YH3	A0A0R3NS75	Q28YH3	Uncharacterized protein, isoform B.	Paired amphipathic helix protein Sin3a.	0.469
DpseGA19867	DpseGA15704	A0A0R3NSZ5	Q29N51	Uncharacterized protein, isoform E.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.426