(45 nodes) Genital disc development network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA27838	Uncharacterized protein, isoform A. (1448 aa)
	DpseGA28528	Uncharacterized protein. (2709 aa)
	DpseGA22607	Uncharacterized protein, isoform A. (1248 aa)
	DpseGA22609	Uncharacterized protein, isoform A. (868 aa)
	DpseGA25997	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1010 aa)
	DpseGA28469	Uncharacterized protein, isoform D. (471 aa)
	DpseGA18104	Uncharacterized protein. (72 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	DpseGA20789	Tyrosine-protein kinase. (798 aa)
	DpseGA17598	Uncharacterized protein, isoform A. (218 aa)
	DpseGA14394	Rhomboid domain-containing protein. (252 aa)
	DpseGA25944	Uncharacterized protein. (186 aa)
	DpseGA23031	Integrin beta; Belongs to the integrin beta chain family. (856 aa)
	DpseGA20908	Receptor protein-tyrosine kinase. (1649 aa)
	A0A0R3NNK2	annotation not available (352 aa)
	A0A0R3NG95	Uncharacterized protein, isoform F. (729 aa)
	DpseGA12709	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DpseGA14567	Homeobox domain-containing protein. (413 aa)
	DpseGA18550	Ski_Sno domain-containing protein. (1032 aa)
	DpseGA18149	Uncharacterized protein, isoform A. (642 aa)
	DpseGA19364	Uncharacterized protein. (691 aa)
	DpseGA21827	Uncharacterized protein, isoform A. (1614 aa)
	rho	Rho; Belongs to the peptidase S54 family. (373 aa)
	DpseGA21581	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1035 aa)
	DpseGA18236	Uncharacterized protein. (479 aa)
	Q29BW2	Uncharacterized protein. (553 aa)
	Q299U9	Uncharacterized protein. (442 aa)
	Q299U8	Uncharacterized protein. (468 aa)
	Q299A1	Dual specificity phosphatase 10. (489 aa)
	Q297P2	Uncharacterized protein, isoform B. (557 aa)
	DpseGA17599	Uncharacterized protein, isoform D. (891 aa)
	Q293L2	Uncharacterized protein, isoform A. (751 aa)
	Q293G6	Uncharacterized protein. (663 aa)
	ken	Transcription factor Ken; Transcription factor required for terminalia development. Negative regulator of the JAK/STAT pathway: represses JAK/STAT- dependent expression of ventral veins lacking (vvl) in the posterior spiracles (By similarity). (569 aa)
	Q292N5	ESCRT-II complex subunit VPS25. (174 aa)
	Dpse_en	Homeobox protein engrailed. (576 aa)
	Q290N6	Uncharacterized protein. (428 aa)
	otk	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity). (1037 aa)
	Q28Y93	Mediator of RNA polymerase II transcription subunit 29. (189 aa)
	Q28Y68	Uncharacterized protein. (1299 aa)
	Q28XM9	Uncharacterized protein, isoform A. (1439 aa)
	I5AP43	Homeobox protein abdominal-B and related proteins. (328 aa)
	B5DXT9	Uncharacterized protein. (702 aa)
	B5DWG2	Uncharacterized protein, isoform A. (568 aa)
	B5DVG8	Uncharacterized protein. (2876 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NG95	DpseGA22609	A0A0R3NG95	B5DLK1	Uncharacterized protein, isoform F.	Uncharacterized protein, isoform A.	0.751
A0A0R3NG95	DpseGA28469	A0A0R3NG95	A0A0R3P8I5	Uncharacterized protein, isoform F.	Uncharacterized protein, isoform D.	0.468
A0A0R3NG95	Q293L2	A0A0R3NG95	Q293L2	Uncharacterized protein, isoform F.	Uncharacterized protein, isoform A.	0.543
A0A0R3NNK2	DpseGA28528	A0A0R3NNK2	B5DM97	annotation not available	Uncharacterized protein.	0.495
A0A0R3NNK2	wg	A0A0R3NNK2	Q29N82	annotation not available	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.449
B5DWG2	I5AP43	B5DWG2	I5AP43	Uncharacterized protein, isoform A.	Homeobox protein abdominal-B and related proteins.	0.775
B5DXT9	rho	B5DXT9	Q29FG3	Uncharacterized protein.	Rho; Belongs to the peptidase S54 family.	0.570
DpseGA12709	DpseGA22607	Q29M17	B5DLK8	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Uncharacterized protein, isoform A.	0.407
DpseGA17598	DpseGA19364	Q29MK6	Q29JZ9	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.474
DpseGA17598	DpseGA25944	Q29MK6	A0A0R3NZT7	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.905
DpseGA17598	Q28XM9	Q29MK6	Q28XM9	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.402
DpseGA17599	otk	A0A0R3P267	Q290N5	Uncharacterized protein, isoform D.	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).	0.649
DpseGA18149	Q28XM9	Q29LI5	Q28XM9	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.473
DpseGA18149	rho	Q29LI5	Q29FG3	Uncharacterized protein, isoform A.	Rho; Belongs to the peptidase S54 family.	0.565
DpseGA18236	Q28XM9	Q29EI0	Q28XM9	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.967
DpseGA18236	rho	Q29EI0	Q29FG3	Uncharacterized protein.	Rho; Belongs to the peptidase S54 family.	0.492
DpseGA19364	DpseGA17598	Q29JZ9	Q29MK6	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.474
DpseGA19364	DpseGA25944	Q29JZ9	A0A0R3NZT7	Uncharacterized protein.	Uncharacterized protein.	0.474
DpseGA20789	DpseGA22607	Q29MM7	B5DLK8	Tyrosine-protein kinase.	Uncharacterized protein, isoform A.	0.485
DpseGA20908	DpseGA23031	A0A0R3NSX3	A0A0R3NYM7	Receptor protein-tyrosine kinase.	Integrin beta; Belongs to the integrin beta chain family.	0.470