(82 nodes) Wing disc pattern formation network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q291Y2	Uncharacterized protein. (500 aa)
	Q291I7	Uncharacterized protein. (622 aa)
	Dpse_en	Homeobox protein engrailed. (576 aa)
	Q290Y6	Uncharacterized protein. (803 aa)
	Q28Y68	Uncharacterized protein. (1299 aa)
	Dpse_vg	Vg. (439 aa)
	Q28XG8	Uncharacterized protein, isoform A. (974 aa)
	N6VF72	Uncharacterized protein. (2426 aa)
	I5APT4	Uncharacterized protein, isoform M. (1857 aa)
	B5DZD8	Human immunodeficiency virus type I enhancer-binding protein. (2641 aa)
	B5DWT5	Uncharacterized protein. (1390 aa)
	B5DW27	ATP-binding cassette, subfamily C (CFTR/MRP), member 4. (1312 aa)
	DpseGA29147	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (204 aa)
	DpseGA28721	MNNL domain-containing protein. (102 aa)
	DpseGA29225	Uncharacterized protein. (207 aa)
	DpseGA24014	Uncharacterized protein. (671 aa)
	DpseGA27838	Uncharacterized protein, isoform A. (1448 aa)
	DpseGA28383	Protein kinase domain-containing protein. (332 aa)
	DpseGA28207	Uncharacterized protein. (587 aa)
	DpseGA23962	Uncharacterized protein, isoform F. (1043 aa)
	DpseGA23928	Uncharacterized protein, isoform A. (1115 aa)
	DpseGA23743	ANK_REP_REGION domain-containing protein. (2327 aa)
	DpseGA23541	Uncharacterized protein. (1716 aa)
	DpseGA28528	Uncharacterized protein. (2709 aa)
	DpseGA22741	Optomotor-blind domain-containing protein. (1027 aa)
	DpseGA22759	Uncharacterized protein, isoform A; Belongs to the 14-3-3 family. (250 aa)
	DpseGA28872	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (638 aa)
	DpseGA28973	Mothers against decapentaplegic homolog. (511 aa)
	A0A0R3NEU0	Uncharacterized protein, isoform C. (627 aa)
	DpseGA26057	Uncharacterized protein, isoform A. (3586 aa)
	DpseGA25737	Serine/threonine-protein phosphatase. (309 aa)
	DpseGA25429	Adenylyl cyclase-associated protein; Belongs to the CAP family. (812 aa)
	DpseGA25243	Uncharacterized protein, isoform A. (591 aa)
	DpseGA28563	Uncharacterized protein, isoform C. (788 aa)
	DpseGA23801	Uncharacterized protein, isoform C. (554 aa)
	DpseGA28200	Uncharacterized protein, isoform C. (165 aa)
	DpseGA15086	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (545 aa)
	DpseGA28649	Uncharacterized protein. (178 aa)
	DpseGA22276	Uncharacterized protein, isoform B. (1132 aa)
	DpseGA32151	Uncharacterized protein. (216 aa)
	DpseGA31287	Uncharacterized protein. (68 aa)
	DpseGA31240	Uncharacterized protein. (81 aa)
	DpseGA32181	Uncharacterized protein. (210 aa)
	A0A0R3NNU9	Uncharacterized protein, isoform B. (3305 aa)
	A0A0R3NL31	Uncharacterized protein, isoform A. (578 aa)
	A0A0R3NKI2	Uncharacterized protein, isoform A. (324 aa)
	A0A0R3NJL9	AT-rich interactive domain-containing protein 1. (2809 aa)
	A0A0R3NI42	Uncharacterized protein, isoform D. (2255 aa)
	A0A0R3NG95	Uncharacterized protein, isoform F. (729 aa)
	A0A0R3NG32	Uncharacterized protein. (1222 aa)
	ap	Ap-PA. (469 aa)
	DpseGA16712	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (769 aa)
	DpseGA22138	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2641 aa)
	DpseGA10411	Uncharacterized protein. (429 aa)
	DpseGA18578	Uncharacterized protein, isoform A; Belongs to the mitochondrial carrier (TC 2.A.29) family. (359 aa)
	DpseGA12497	Uncharacterized protein. (995 aa)
	DpseGA18752	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (836 aa)
	smo	Smo; Belongs to the G-protein coupled receptor Fz/Smo family. (1061 aa)
	cbt	Cabut. (452 aa)
	DpseGA12709	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DpseGA18056	Uncharacterized protein, isoform A. (976 aa)
	iHog	Interference hedgehog; Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc). Belongs to the immunoglobulin superfamily. IHOG family. (903 aa)
	DpseGA11481	Uncharacterized protein. (1960 aa)
	DpseGA20664	Uncharacterized protein, isoform A. (381 aa)
	DpseGA19680	Protein kinase domain-containing protein. (811 aa)
	DpseGA11033	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (496 aa)
	DpseGA10976	WW domain-containing protein. (935 aa)
	DpseGA18565	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (527 aa)
	Q29BW2	Uncharacterized protein. (553 aa)
	Q29AY6	Uncharacterized protein. (1096 aa)
	Q299T8	Activin receptor type-2B. (523 aa)
	Q299A8	Uncharacterized protein, isoform A. (573 aa)
	Q297W6	Uncharacterized protein. (1221 aa)
	Q296Y1	Hairy and enhancer of split, invertebrate. (214 aa)
	Q296W0	Uncharacterized protein, isoform A. (262 aa)
	Q295X5	SAP domain-containing ribonucleoprotein. (316 aa)
	Q295V0	Extracellular sulfatase Sulf. (1156 aa)
	Q295N1	Uncharacterized protein, isoform A. (206 aa)
	Q295C4	Uncharacterized protein, isoform B. (962 aa)
	Q293P0	Uncharacterized protein. (852 aa)
	Q293K6	Uncharacterized protein, isoform D. (118 aa)
	Q292R9	Bone morphogenetic protein 7. (459 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NG32	B5DWT5	A0A0R3NG32	B5DWT5	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A0R3NG32	DpseGA25243	A0A0R3NG32	B5DHG8	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.755
A0A0R3NG32	DpseGA28528	A0A0R3NG32	B5DM97	Uncharacterized protein.	Uncharacterized protein.	0.979
A0A0R3NG32	DpseGA28721	A0A0R3NG32	B5DUT0	Uncharacterized protein.	MNNL domain-containing protein.	0.430
A0A0R3NG32	Q293P0	A0A0R3NG32	Q293P0	Uncharacterized protein.	Uncharacterized protein.	0.618
A0A0R3NI42	DpseGA25243	A0A0R3NI42	B5DHG8	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform A.	0.565
A0A0R3NKI2	DpseGA23928	A0A0R3NKI2	B5DQ99	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.462
A0A0R3NL31	DpseGA12709	A0A0R3NL31	Q29M17	Uncharacterized protein, isoform A.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.928
A0A0R3NL31	DpseGA18056	A0A0R3NL31	Q29LM8	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.465
A0A0R3NL31	DpseGA28973	A0A0R3NL31	B5DJI3	Uncharacterized protein, isoform A.	Mothers against decapentaplegic homolog.	0.958
A0A0R3NL31	Q292R9	A0A0R3NL31	Q292R9	Uncharacterized protein, isoform A.	Bone morphogenetic protein 7.	0.783
A0A0R3NL31	Q299T8	A0A0R3NL31	Q299T8	Uncharacterized protein, isoform A.	Activin receptor type-2B.	0.886
A0A0R3NNU9	DpseGA18752	A0A0R3NNU9	Q29NY2	Uncharacterized protein, isoform B.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.587
A0A0R3NNU9	DpseGA24014	A0A0R3NNU9	B5DS99	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.556
A0A0R3NNU9	DpseGA31240	A0A0R3NNU9	A0A0R3NWI2	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.556
A0A0R3NNU9	DpseGA31287	A0A0R3NNU9	A0A0R3NXG0	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.556
A0A0R3NNU9	DpseGA32151	A0A0R3NNU9	A0A0R3P1F8	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.556
A0A0R3NNU9	DpseGA32181	A0A0R3NNU9	A0A0R3NW16	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.556
B5DWT5	A0A0R3NG32	B5DWT5	A0A0R3NG32	Uncharacterized protein.	Uncharacterized protein.	0.900
B5DWT5	DpseGA25243	B5DWT5	B5DHG8	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.755