(28 nodes) Leg disc pattern formation network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA31562	Uncharacterized protein. (235 aa)
	A0A0R3NG95	Uncharacterized protein, isoform F. (729 aa)
	A0A0R3NGF8	Uncharacterized protein. (142 aa)
	A0A0R3NNC1	Uncharacterized protein, isoform A. (263 aa)
	A0A0R3NNK2	annotation not available (352 aa)
	A0A0R3NPB8	Uncharacterized protein. (147 aa)
	DpseGA32035	Protein kinase domain-containing protein. (157 aa)
	ap	Ap-PA. (469 aa)
	DpseGA12497	Uncharacterized protein. (995 aa)
	DpseGA19742	Uncharacterized protein. (604 aa)
	DpseGA18550	Ski_Sno domain-containing protein. (1032 aa)
	DpseGA10943	Uncharacterized protein, isoform C. (497 aa)
	DpseGA22115	C2H2-type domain-containing protein. (565 aa)
	rho	Rho; Belongs to the peptidase S54 family. (373 aa)
	DpseGA11431	Uncharacterized protein, isoform A; Belongs to the peptidase S54 family. (336 aa)
	DpseGA10349	Uncharacterized protein. (637 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	Q28ZT5	Low density lipoprotein receptor-related protein 5/6. (1687 aa)
	Q28XM9	Uncharacterized protein, isoform A. (1439 aa)
	B5E0S0	Uncharacterized protein, isoform A. (288 aa)
	B5DZ64	Zinc finger protein AEBP2. (1725 aa)
	DpseGA28799	Uncharacterized protein, isoform B. (134 aa)
	DpseGA28287	Uncharacterized protein, isoform A. (626 aa)
	DpseGA28280	Homeobox domain-containing protein. (658 aa)
	DpseGA23083	Uncharacterized protein. (365 aa)
	DpseGA25466	Uncharacterized protein. (677 aa)
	DpseGA30601	Uncharacterized protein. (113 aa)
	DpseGA15199	Uncharacterized protein, isoform B. (1576 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NG95	Ras85D	A0A0R3NG95	Q295X7	Uncharacterized protein, isoform F.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.430
A0A0R3NNK2	DpseGA10943	A0A0R3NNK2	Q29GR9	annotation not available	Uncharacterized protein, isoform C.	0.499
A0A0R3NNK2	ap	A0A0R3NNK2	Q8I1D1	annotation not available	Ap-PA.	0.422
DpseGA10349	Q28XM9	Q29E55	Q28XM9	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.997
DpseGA10349	Ras85D	Q29E55	Q295X7	Uncharacterized protein.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.457
DpseGA10943	A0A0R3NNK2	Q29GR9	A0A0R3NNK2	Uncharacterized protein, isoform C.	annotation not available	0.499
DpseGA28280	DpseGA28287	B5DM43	B5DM45	Homeobox domain-containing protein.	Uncharacterized protein, isoform A.	0.839
DpseGA28287	DpseGA28280	B5DM45	B5DM43	Uncharacterized protein, isoform A.	Homeobox domain-containing protein.	0.839
DpseGA32035	Q28XM9	A0A0R3NW60	Q28XM9	Protein kinase domain-containing protein.	Uncharacterized protein, isoform A.	0.429
DpseGA32035	Ras85D	A0A0R3NW60	Q295X7	Protein kinase domain-containing protein.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.743
Q28XM9	DpseGA10349	Q28XM9	Q29E55	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.997
Q28XM9	DpseGA32035	Q28XM9	A0A0R3NW60	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein.	0.429
Q28XM9	Ras85D	Q28XM9	Q295X7	Uncharacterized protein, isoform A.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.976
Q28XM9	rho	Q28XM9	Q29FG3	Uncharacterized protein, isoform A.	Rho; Belongs to the peptidase S54 family.	0.705
Ras85D	A0A0R3NG95	Q295X7	A0A0R3NG95	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	Uncharacterized protein, isoform F.	0.430
Ras85D	DpseGA10349	Q295X7	Q29E55	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	Uncharacterized protein.	0.457
Ras85D	DpseGA32035	Q295X7	A0A0R3NW60	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	Protein kinase domain-containing protein.	0.743
Ras85D	Q28XM9	Q295X7	Q28XM9	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	Uncharacterized protein, isoform A.	0.976
ap	A0A0R3NNK2	Q8I1D1	A0A0R3NNK2	Ap-PA.	annotation not available	0.422
rho	Q28XM9	Q29FG3	Q28XM9	Rho; Belongs to the peptidase S54 family.	Uncharacterized protein, isoform A.	0.705