(16 nodes) Chitin-based larval cuticle pattern formation network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA14615	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (619 aa)
	I5ANM9	Uncharacterized protein, isoform A. (785 aa)
	DpseGA22660	Uncharacterized protein, isoform H. (880 aa)
	DpseGA20362	Uncharacterized protein, isoform D. (536 aa)
	DpseGA14746	Uncharacterized protein, isoform D. (1364 aa)
	DpseGA15199	Uncharacterized protein, isoform B. (1576 aa)
	Q298J2	Adenomatosis polyposis coli protein. (1088 aa)
	Q298N7	GTP-binding protein SAR1. (193 aa)
	Q298V3	Adenomatosis polyposis coli protein. (2440 aa)
	Q29BI5	Protein transport protein SEC13. (356 aa)
	Q29C79	Uncharacterized protein, isoform A. (762 aa)
	DpseGA17335	Uncharacterized protein. (245 aa)
	DpseGA21999	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (818 aa)
	DpseGA14769	HMG box domain-containing protein. (798 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	ck	Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high- duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction [...] (2168 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DpseGA14615	DpseGA14746	Q2LZT5	A0A0R3P194	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein, isoform D.	0.431
DpseGA14615	DpseGA22660	Q2LZT5	B5DLC5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein, isoform H.	0.473
DpseGA14615	Q29C79	Q2LZT5	Q29C79	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein, isoform A.	0.773
DpseGA14615	wg	Q2LZT5	Q29N82	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.967
DpseGA14746	DpseGA14615	A0A0R3P194	Q2LZT5	Uncharacterized protein, isoform D.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.431
DpseGA14746	DpseGA14769	A0A0R3P194	Q29JU4	Uncharacterized protein, isoform D.	HMG box domain-containing protein.	0.524
DpseGA14746	DpseGA15199	A0A0R3P194	A0A0R3P0Y3	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform B.	0.525
DpseGA14746	Q298J2	A0A0R3P194	Q298J2	Uncharacterized protein, isoform D.	Adenomatosis polyposis coli protein.	0.701
DpseGA14746	Q298V3	A0A0R3P194	Q298V3	Uncharacterized protein, isoform D.	Adenomatosis polyposis coli protein.	0.704
DpseGA14746	Q29C79	A0A0R3P194	Q29C79	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform A.	0.673
DpseGA14746	wg	A0A0R3P194	Q29N82	Uncharacterized protein, isoform D.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.755
DpseGA14769	DpseGA14746	Q29JU4	A0A0R3P194	HMG box domain-containing protein.	Uncharacterized protein, isoform D.	0.524
DpseGA15199	DpseGA14746	A0A0R3P0Y3	A0A0R3P194	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform D.	0.525
DpseGA17335	Q298N7	Q29D12	Q298N7	Uncharacterized protein.	GTP-binding protein SAR1.	0.463
DpseGA21999	DpseGA22660	Q29DI2	B5DLC5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein, isoform H.	0.510
DpseGA21999	Q29C79	Q29DI2	Q29C79	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein, isoform A.	0.600
DpseGA21999	wg	Q29DI2	Q29N82	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.972
DpseGA22660	DpseGA14615	B5DLC5	Q2LZT5	Uncharacterized protein, isoform H.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.473
DpseGA22660	DpseGA21999	B5DLC5	Q29DI2	Uncharacterized protein, isoform H.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.510
DpseGA22660	Q298J2	B5DLC5	Q298J2	Uncharacterized protein, isoform H.	Adenomatosis polyposis coli protein.	0.826