(83 nodes) Regulation of hippo signaling network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA30758	Uncharacterized protein, isoform A. (336 aa)
	DpseGA28105	FERM domain-containing protein. (122 aa)
	DpseGA33039	Uncharacterized protein. (54 aa)
	Q29CD4	Uncharacterized protein, isoform D. (439 aa)
	DpseGA16614	Uncharacterized protein. (274 aa)
	DpseGA13409	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1071 aa)
	DpseGA20043	Uncharacterized protein, isoform A. (909 aa)
	Q29AF1	Uncharacterized protein. (199 aa)
	Q29A43	Interleukin-1 receptor-associated kinase 1. (500 aa)
	Q299W4	Mitogen-activated protein kinase kinase kinase 4. (1574 aa)
	Q298J9	Uncharacterized protein, isoform A. (1107 aa)
	DpseGA10369	Uncharacterized protein. (1855 aa)
	DpseGA14285	RING-type domain-containing protein. (315 aa)
	DpseGA15150	Uncharacterized protein. (184 aa)
	DpseGA10361	Uncharacterized protein, isoform A. (755 aa)
	DpseGA17399	Uncharacterized protein, isoform B. (5256 aa)
	DpseGA18145	Uncharacterized protein, isoform C; Belongs to the protein kinase superfamily. (353 aa)
	DpseGA17967	FERM domain-containing protein. (1515 aa)
	DpseGA11750	Uncharacterized protein, isoform D. (1351 aa)
	DpseGA19649	Uncharacterized protein. (1976 aa)
	DpseGA18056	Uncharacterized protein, isoform A. (976 aa)
	DpseGA20320	Mitogen-activated protein kinase. (365 aa)
	DpseGA10119	Uncharacterized protein. (325 aa)
	DpseGA21829	Uncharacterized protein. (1260 aa)
	DpseGA13113	WD_REPEATS_REGION domain-containing protein. (343 aa)
	DpseGA18086	Protein kinase domain-containing protein. (1481 aa)
	DpseGA15193	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (337 aa)
	DpseGA11504	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
	DpseGA12841	FERM domain-containing protein. (636 aa)
	DpseGA13337	Uncharacterized protein, isoform A; Belongs to the peptidase C19 family. (1144 aa)
	DpseGA20611	Protein kinase domain-containing protein. (915 aa)
	DpseGA12831	Uncharacterized protein, isoform A. (1034 aa)
	DpseGA14321	Protein kinase domain-containing protein. (1356 aa)
	DpseGA18237	Coronin; Belongs to the WD repeat coronin family. (1303 aa)
	DpseGA11051	Uncharacterized protein, isoform B. (929 aa)
	DpseGA15168	Uncharacterized protein, isoform C. (2464 aa)
	DpseGA28417	Uncharacterized protein, isoform D. (1057 aa)
	DpseGA28338	Tyrosine-protein kinase. (552 aa)
	DpseGA25880	Uncharacterized protein, isoform A. (664 aa)
	DpseGA25737	Serine/threonine-protein phosphatase. (309 aa)
	DpseGA26057	Uncharacterized protein, isoform A. (3586 aa)
	DpseGA29082	Uncharacterized protein, isoform A. (967 aa)
	DpseGA22759	Uncharacterized protein, isoform A; Belongs to the 14-3-3 family. (250 aa)
	DpseGA22536	Uncharacterized protein. (692 aa)
	DpseGA22282	Uncharacterized protein. (194 aa)
	DpseGA24328	Uncharacterized protein. (1561 aa)
	DpseGA28339	Protein kinase domain-containing protein. (234 aa)
	DpseGA27838	Uncharacterized protein, isoform A. (1448 aa)
	DpseGA20319	Uncharacterized protein, isoform E. (744 aa)
	DpseGA25301	Uncharacterized protein, isoform C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1480 aa)
	DpseGA32929	Uncharacterized protein. (172 aa)
	DpseGA32581	Uncharacterized protein. (182 aa)
	DpseGA10030	Uncharacterized protein, isoform E. (1397 aa)
	A0A0R3NU81	Uncharacterized protein, isoform B. (248 aa)
	A0A0R3NSV7	MAP/microtubule affinity-regulating kinase. (1192 aa)
	B5DX68	F-box and WD-40 domain protein 1/11. (590 aa)
	B5DYA7	Ras association domain-containing protein 2/4. (822 aa)
	B5DZC0	Uncharacterized protein. (371 aa)
	B5DZE2	Uncharacterized protein, isoform K. (3989 aa)
	I5APB1	Uncharacterized protein, isoform C. (1114 aa)
	I5APZ2	Uncharacterized protein. (214 aa)
	N6W5Y1	annotation not available (1271 aa)
	Q28WY5	Uncharacterized protein. (210 aa)
	Q28XI9	G protein-coupled receptor kinase interactor 2. (732 aa)
	Q28Y68	Uncharacterized protein. (1299 aa)
	Q28YB0	Uncharacterized protein. (774 aa)
	Q28Z37	E3 ubiquitin ligase SMURF1/2. (1096 aa)
	Q291A6	E3 ubiquitin-protein ligase SH3RF. (858 aa)
	Q292F7	SH3 and multiple ankyrin repeat domains protein. (1946 aa)
	Q292Z2	Uncharacterized protein. (223 aa)
	Q293Z7	Uncharacterized protein, isoform A. (532 aa)
	Q294V1	RAC serine/threonine-protein kinase. (530 aa)
	A0A0R3NS54	Tyrosine-protein kinase receptor torso. (939 aa)
	A0A0R3NRT2	Calmodulin-regulated spectrin-associated protein. (1815 aa)
	A0A0R3NQH0	Uncharacterized protein, isoform B. (1874 aa)
	A0A0R3NP93	annotation not available (982 aa)
	A0A0R3NLK6	Serine/threonine-protein kinase SIK3. (1494 aa)
	A0A0R3NJD9	Uncharacterized protein, isoform G. (2610 aa)
	A0A0R3NI42	Uncharacterized protein, isoform D. (2255 aa)
	A0A0R3NGZ0	Uncharacterized protein, isoform A. (465 aa)
	Q296P4	F-box and leucine-rich repeat protein 7. (787 aa)
	Q296W0	Uncharacterized protein, isoform A. (262 aa)
	B5DVF7	Uncharacterized protein. (1280 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NI42	A0A0R3NP93	A0A0R3NI42	A0A0R3NP93	Uncharacterized protein, isoform D.	annotation not available	0.649
A0A0R3NI42	B5DVF7	A0A0R3NI42	B5DVF7	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.502
A0A0R3NI42	DpseGA11750	A0A0R3NI42	Q29MZ4	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform D.	0.429
A0A0R3NI42	DpseGA17967	A0A0R3NI42	Q29N45	Uncharacterized protein, isoform D.	FERM domain-containing protein.	0.971
A0A0R3NJD9	A0A0R3NP93	A0A0R3NJD9	A0A0R3NP93	Uncharacterized protein, isoform G.	annotation not available	0.646
A0A0R3NJD9	B5DVF7	A0A0R3NJD9	B5DVF7	Uncharacterized protein, isoform G.	Uncharacterized protein.	0.683
A0A0R3NJD9	DpseGA10369	A0A0R3NJD9	Q2M0M0	Uncharacterized protein, isoform G.	Uncharacterized protein.	0.973
A0A0R3NJD9	DpseGA18056	A0A0R3NJD9	Q29LM8	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform A.	0.514
A0A0R3NJD9	DpseGA19649	A0A0R3NJD9	Q29M21	Uncharacterized protein, isoform G.	Uncharacterized protein.	0.409
A0A0R3NJD9	I5APB1	A0A0R3NJD9	I5APB1	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform C.	0.568
A0A0R3NJD9	Q28Z37	A0A0R3NJD9	Q28Z37	Uncharacterized protein, isoform G.	E3 ubiquitin ligase SMURF1/2.	0.517
A0A0R3NJD9	Q294V1	A0A0R3NJD9	Q294V1	Uncharacterized protein, isoform G.	RAC serine/threonine-protein kinase.	0.456
A0A0R3NLK6	A0A0R3NP93	A0A0R3NLK6	A0A0R3NP93	Serine/threonine-protein kinase SIK3.	annotation not available	0.428
A0A0R3NLK6	A0A0R3NU81	A0A0R3NLK6	A0A0R3NU81	Serine/threonine-protein kinase SIK3.	Uncharacterized protein, isoform B.	0.460
A0A0R3NLK6	DpseGA22759	A0A0R3NLK6	B5DKW8	Serine/threonine-protein kinase SIK3.	Uncharacterized protein, isoform A; Belongs to the 14-3-3 family.	0.460
A0A0R3NLK6	DpseGA28338	A0A0R3NLK6	A0A0R3P952	Serine/threonine-protein kinase SIK3.	Tyrosine-protein kinase.	0.447
A0A0R3NLK6	DpseGA28339	A0A0R3NLK6	B5DRC6	Serine/threonine-protein kinase SIK3.	Protein kinase domain-containing protein.	0.456
A0A0R3NLK6	Q296W0	A0A0R3NLK6	Q296W0	Serine/threonine-protein kinase SIK3.	Uncharacterized protein, isoform A.	0.460
A0A0R3NP93	A0A0R3NI42	A0A0R3NP93	A0A0R3NI42	annotation not available	Uncharacterized protein, isoform D.	0.649
A0A0R3NP93	A0A0R3NJD9	A0A0R3NP93	A0A0R3NJD9	annotation not available	Uncharacterized protein, isoform G.	0.646