(66 nodes) Response to decreased oxygen levels network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q29BY5	Uncharacterized protein. (544 aa)
	DpseGA10498	Prohibitin. (276 aa)
	DpseGA19636	Uncharacterized protein. (365 aa)
	DpseGA13429	Uncharacterized protein. (1422 aa)
	GA21628	UPF0389 protein GA21628. (127 aa)
	DpseGA21595	Uncharacterized protein, isoform A. (570 aa)
	DpseGA19839	Sorting nexin; Belongs to the sorting nexin family. (561 aa)
	DpseGA16811	Uncharacterized protein, isoform E. (1836 aa)
	DpseGA18202	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (184 aa)
	DpseGA20432	Uncharacterized protein. (248 aa)
	DpseGA17499	Uncharacterized protein, isoform B. (520 aa)
	DpseGA22114	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2054 aa)
	DpseGA15423	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (352 aa)
	DpseGA20693	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (140 aa)
	DpseGA15518	Uncharacterized protein. (942 aa)
	DpseGA11612	Uncharacterized protein. (614 aa)
	DpseGA12519	Uncharacterized protein. (787 aa)
	DpseGA10496	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (254 aa)
	DpseGA19997	Rap-GAP domain-containing protein. (1864 aa)
	Q296C8	Guanylate cyclase, other. (667 aa)
	Q298J9	Uncharacterized protein, isoform A. (1107 aa)
	Q299A4	ADP-ribosylation factor-like protein 8. (186 aa)
	Q29AN0	Mitochondrial import inner membrane translocase subunit TIM44. (458 aa)
	Q29B15	Heat shock 70kDa protein 1/2/6/8. (641 aa)
	Q29B22	Uncharacterized protein. (379 aa)
	Q29BH1	Uncharacterized protein. (325 aa)
	Q29BT8	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1. (335 aa)
	Q29C99	Transient receptor potential cation channel subfamily C member 4. (1251 aa)
	A0A0R3NEH1	Uncharacterized protein, isoform D. (1670 aa)
	A0A0R3NPZ4	Transient-receptor-potential-like protein. (1147 aa)
	A0A0R3NQ37	Uncharacterized protein, isoform B. (679 aa)
	A0A0R3NSP1	Cyclic nucleotide gated channel alpha 3. (848 aa)
	DpseGA19056	IRS-type PTB domain-containing protein. (272 aa)
	DpseGA11711	Uncharacterized protein, isoform Q. (738 aa)
	DpseGA25857	Uncharacterized protein, isoform B. (2002 aa)
	DpseGA18136	Uncharacterized protein, isoform B. (346 aa)
	DpseGA31983	ULP_PROTEASE domain-containing protein. (71 aa)
	DpseGA25872	Uncharacterized protein, isoform C. (2152 aa)
	DpseGA28872	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (638 aa)
	DpseGA22933	Uncharacterized protein. (1602 aa)
	DpseGA22687	Uncharacterized protein, isoform A. (122 aa)
	DpseGA27773	Fork-head domain-containing protein. (1242 aa)
	DpseGA29178	Uncharacterized protein. (1209 aa)
	DpseGA22536	Uncharacterized protein. (692 aa)
	DpseGA24323	Uncharacterized protein, isoform A. (297 aa)
	DpseGA28326	SUI1 domain-containing protein. (110 aa)
	B5DW13	Uncharacterized protein. (209 aa)
	B5DW14	Uncharacterized protein. (218 aa)
	B5DW27	ATP-binding cassette, subfamily C (CFTR/MRP), member 4. (1312 aa)
	B5DXQ8	Sentrin-specific protease 1. (328 aa)
	B5DXX5	Uncharacterized protein, isoform E. (1089 aa)
	B5DYR5	Insulin-like growth factor 1 receptor. (2293 aa)
	Dpse_glob1	Globin 1, isoform A. (154 aa)
	I5AN92	Ecdysone-induced protein 93F, isoform B. (1325 aa)
	Q28WW5	LETM1 and EF-hand domain-containing protein 1, mitochondrial. (1034 aa)
	Q28YI9	Uncharacterized protein, isoform A. (428 aa)
	Q28YM8	Translation initiation factor eIF-2B subunit gamma. (457 aa)
	Q290X0	ATP-binding cassette, subfamily B (MDR/TAP), member 1. (1300 aa)
	Q291B0	Uncharacterized protein. (2497 aa)
	Q291Y2	Uncharacterized protein. (500 aa)
	Q294H9	Aryl hydrocarbon receptor nuclear translocator. (646 aa)
	Q294U5	Inhibitor of nuclear factor kappa-B kinase subunit beta. (725 aa)
	Q295L2	Serine/threonine-protein kinase TTK/MPS1. (648 aa)
	Q296A0	Uncharacterized protein, isoform A. (193 aa)
	Q296B2	Hypoxia-inducible factor prolyl hydroxylase. (489 aa)
	Q296C7	Uncharacterized protein, isoform A. (667 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NEH1	DpseGA10498	A0A0R3NEH1	Q29CK9	Uncharacterized protein, isoform D.	Prohibitin.	0.438
A0A0R3NEH1	DpseGA22536	A0A0R3NEH1	B5DN27	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.667
A0A0R3NEH1	Q294H9	A0A0R3NEH1	Q294H9	Uncharacterized protein, isoform D.	Aryl hydrocarbon receptor nuclear translocator.	0.988
A0A0R3NEH1	Q296B2	A0A0R3NEH1	Q296B2	Uncharacterized protein, isoform D.	Hypoxia-inducible factor prolyl hydroxylase.	0.991
A0A0R3NEH1	Q298J9	A0A0R3NEH1	Q298J9	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform A.	0.445
A0A0R3NPZ4	Q29C99	A0A0R3NPZ4	Q29C99	Transient-receptor-potential-like protein.	Transient receptor potential cation channel subfamily C member 4.	0.738
B5DYR5	DpseGA19056	B5DYR5	A0A0R3NWK0	Insulin-like growth factor 1 receptor.	IRS-type PTB domain-containing protein.	0.998
B5DYR5	DpseGA19997	B5DYR5	Q2M0Y0	Insulin-like growth factor 1 receptor.	Rap-GAP domain-containing protein.	0.449
B5DYR5	DpseGA21595	B5DYR5	Q29DV4	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform A.	0.891
B5DYR5	Q298J9	B5DYR5	Q298J9	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform A.	0.550
DpseGA10496	Q28YM8	Q2M0L5	Q28YM8	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	Translation initiation factor eIF-2B subunit gamma.	0.773
DpseGA10498	A0A0R3NEH1	Q29CK9	A0A0R3NEH1	Prohibitin.	Uncharacterized protein, isoform D.	0.438
DpseGA12519	DpseGA15518	Q29NL4	Q29JK3	Uncharacterized protein.	Uncharacterized protein.	0.557
DpseGA12519	Q298J9	Q29NL4	Q298J9	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.656
DpseGA12519	Q29B15	Q29NL4	Q29B15	Uncharacterized protein.	Heat shock 70kDa protein 1/2/6/8.	0.626
DpseGA15423	Q28YM8	Q29HR5	Q28YM8	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family.	Translation initiation factor eIF-2B subunit gamma.	0.999
DpseGA15518	DpseGA12519	Q29JK3	Q29NL4	Uncharacterized protein.	Uncharacterized protein.	0.557
DpseGA15518	Q298J9	Q29JK3	Q298J9	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.759
DpseGA15518	Q29AN0	Q29JK3	Q29AN0	Uncharacterized protein.	Mitochondrial import inner membrane translocase subunit TIM44.	0.503
DpseGA16811	DpseGA29178	Q29F78	B5DMP8	Uncharacterized protein, isoform E.	Uncharacterized protein.	0.547