(49 nodes) Regulation of multicellular organism growth network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA20737	Uncharacterized protein, isoform C. (1322 aa)
	A0A0R3NKT4	Uncharacterized protein, isoform E. (646 aa)
	DpseGA11107	Uncharacterized protein, isoform B. (748 aa)
	A0A0R3NS54	Tyrosine-protein kinase receptor torso. (939 aa)
	DpseGA19047	Uncharacterized protein, isoform C. (503 aa)
	DpseGA19056	IRS-type PTB domain-containing protein. (272 aa)
	DpseGA19279	Uncharacterized protein, isoform B. (438 aa)
	DpseGA28240	Uncharacterized protein, isoform B. (522 aa)
	DpseGA30819	Uncharacterized protein. (219 aa)
	DpseGA28399	Uncharacterized protein, isoform D. (915 aa)
	DpseGA28236	Uncharacterized protein. (117 aa)
	DpseGA32364	Uncharacterized protein. (123 aa)
	DpseGA22847	Uncharacterized protein. (156 aa)
	DpseGA22933	Uncharacterized protein. (1602 aa)
	DpseGA23412	Uncharacterized protein, isoform A; Belongs to the fatty acid desaturase type 1 family. (379 aa)
	DpseGA28237	Uncharacterized protein. (307 aa)
	DpseGA22236	Uncharacterized protein. (122 aa)
	DpseGA23336	Uncharacterized protein. (261 aa)
	B5DVF9	Synaptotagmin-like protein. (4047 aa)
	B5DVY6	Scaffold protein salvador. (587 aa)
	B5DWM0	Nuclear GTP-binding protein. (583 aa)
	B5DX59	Uncharacterized protein. (2795 aa)
	B5DXC1	Disintegrin and metalloproteinase domain-containing protein 17. (743 aa)
	B5DYA7	Ras association domain-containing protein 2/4. (822 aa)
	B5DYR5	Insulin-like growth factor 1 receptor. (2293 aa)
	B5E0Z6	Uncharacterized protein. (122 aa)
	B5E1J5	Uncharacterized protein, isoform A. (424 aa)
	Q28Z96	Endoplasmic reticulum protein 29. (261 aa)
	Tctp	Translationally-controlled tumor protein homolog; Involved in calcium binding and microtubule stabilization. Belongs to the TCTP family. (172 aa)
	Q294V1	RAC serine/threonine-protein kinase. (530 aa)
	Q295M0	Ras association domain-containing protein 7/8. (615 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	Q296J3	Uncharacterized protein. (849 aa)
	Q298B5	Forkhead box protein A2, hepatocyte nuclear factor 3-beta. (613 aa)
	Q298Q1	MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5. (565 aa)
	Q29AR5	Uncharacterized protein, isoform A. (357 aa)
	Q29AY5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1112 aa)
	Dpse_Desat1	Stearoyl-CoA desaturase (Delta-9 desaturase). (383 aa)
	Dpse_Tl	Protein toll. (1120 aa)
	ey	Ey, isoform A. (896 aa)
	DpseGA21570	Uncharacterized protein. (704 aa)
	DpseGA10484	Protein kinase domain-containing protein. (224 aa)
	DpseGA11504	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
	DpseGA10565	BHLH domain-containing protein. (734 aa)
	DpseGA15481	Uncharacterized protein, isoform A. (839 aa)
	DpseGA20715	BZIP domain-containing protein. (465 aa)
	DpseGA20320	Mitogen-activated protein kinase. (365 aa)
	sNPF	sNPF-associated peptide; Plays a role in controlling food intake and regulating body size; Belongs to the NPY family. (290 aa)
	DpseGA20322	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (616 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NS54	Q29AR5	A0A0R3NS54	Q29AR5	Tyrosine-protein kinase receptor torso.	Uncharacterized protein, isoform A.	0.510
A0A0R3NS54	Q29AY5	A0A0R3NS54	Q29AY5	Tyrosine-protein kinase receptor torso.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.506
A0A0R3NS54	Ras85D	A0A0R3NS54	Q295X7	Tyrosine-protein kinase receptor torso.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.401
B5DVY6	B5DYA7	B5DVY6	B5DYA7	Scaffold protein salvador.	Ras association domain-containing protein 2/4.	0.899
B5DX59	DpseGA15481	B5DX59	Q29IQ6	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.569
B5DX59	DpseGA19047	B5DX59	A0A0R3NW51	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.625
B5DX59	Q294V1	B5DX59	Q294V1	Uncharacterized protein.	RAC serine/threonine-protein kinase.	0.549
B5DX59	Q29AY5	B5DX59	Q29AY5	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.449
B5DX59	Ras85D	B5DX59	Q295X7	Uncharacterized protein.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.806
B5DYA7	B5DVY6	B5DYA7	B5DVY6	Ras association domain-containing protein 2/4.	Scaffold protein salvador.	0.899
B5DYA7	Q295M0	B5DYA7	Q295M0	Ras association domain-containing protein 2/4.	Ras association domain-containing protein 7/8.	0.410
B5DYR5	DpseGA19047	B5DYR5	A0A0R3NW51	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform C.	0.609
B5DYR5	DpseGA19056	B5DYR5	A0A0R3NWK0	Insulin-like growth factor 1 receptor.	IRS-type PTB domain-containing protein.	0.998
B5DYR5	DpseGA22847	B5DYR5	B5DKG0	Insulin-like growth factor 1 receptor.	Uncharacterized protein.	0.957
B5DYR5	DpseGA28399	B5DYR5	A0A0R3P909	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform D.	0.497
B5DYR5	Q29AY5	B5DYR5	Q29AY5	Insulin-like growth factor 1 receptor.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.958
B5DYR5	Ras85D	B5DYR5	Q295X7	Insulin-like growth factor 1 receptor.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.923
DpseGA10565	Q294V1	Q29IE0	Q294V1	BHLH domain-containing protein.	RAC serine/threonine-protein kinase.	0.460
DpseGA11504	DpseGA20320	Q29IB7	Q29K65	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.990
DpseGA11504	Q294V1	Q29IB7	Q294V1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	RAC serine/threonine-protein kinase.	0.462