(8 nodes) Clathrin-coated endocytic vesicle network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q29B05	AP-2 complex subunit sigma-1. (142 aa)
	Q298U5	AP-2 complex subunit mu-1. (437 aa)
	I5ANM2	Uncharacterized protein. (581 aa)
	DpseGA22551	Uncharacterized protein. (88 aa)
	alpha-Adaptin	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity). (939 aa)
	DpseGA11682	AP complex subunit beta. (924 aa)
	DpseGA21476	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1584 aa)
	Q29A70	Phosphatidylinositol 4-phosphatase. (1145 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DpseGA11682	DpseGA21476	Q29H04	Q29CS2	AP complex subunit beta.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.974
DpseGA11682	DpseGA22551	Q29H04	B5DSP7	AP complex subunit beta.	Uncharacterized protein.	0.961
DpseGA11682	Q298U5	Q29H04	Q298U5	AP complex subunit beta.	AP-2 complex subunit mu-1.	0.998
DpseGA11682	Q29B05	Q29H04	Q29B05	AP complex subunit beta.	AP-2 complex subunit sigma-1.	0.995
DpseGA11682	alpha-Adaptin	Q29H04	Q29N38	AP complex subunit beta.	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity).	0.995
DpseGA21476	DpseGA11682	Q29CS2	Q29H04	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP complex subunit beta.	0.974
DpseGA21476	Q298U5	Q29CS2	Q298U5	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit mu-1.	0.831
DpseGA21476	Q29B05	Q29CS2	Q29B05	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit sigma-1.	0.810
DpseGA21476	alpha-Adaptin	Q29CS2	Q29N38	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity).	0.908
DpseGA22551	DpseGA11682	B5DSP7	Q29H04	Uncharacterized protein.	AP complex subunit beta.	0.961
DpseGA22551	Q298U5	B5DSP7	Q298U5	Uncharacterized protein.	AP-2 complex subunit mu-1.	0.831
DpseGA22551	Q29B05	B5DSP7	Q29B05	Uncharacterized protein.	AP-2 complex subunit sigma-1.	0.810
DpseGA22551	alpha-Adaptin	B5DSP7	Q29N38	Uncharacterized protein.	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity).	0.863
Q298U5	DpseGA11682	Q298U5	Q29H04	AP-2 complex subunit mu-1.	AP complex subunit beta.	0.998
Q298U5	DpseGA21476	Q298U5	Q29CS2	AP-2 complex subunit mu-1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.831
Q298U5	DpseGA22551	Q298U5	B5DSP7	AP-2 complex subunit mu-1.	Uncharacterized protein.	0.831
Q298U5	Q29B05	Q298U5	Q29B05	AP-2 complex subunit mu-1.	AP-2 complex subunit sigma-1.	0.999
Q298U5	alpha-Adaptin	Q298U5	Q29N38	AP-2 complex subunit mu-1.	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity).	0.999
Q29B05	DpseGA11682	Q29B05	Q29H04	AP-2 complex subunit sigma-1.	AP complex subunit beta.	0.995
Q29B05	DpseGA21476	Q29B05	Q29CS2	AP-2 complex subunit sigma-1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.810