(9 nodes) Sex comb development network (Drosophila pseudoobscura)

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Your Input:
	DpseGA27749	Uncharacterized protein. (1143 aa)
	DpseGA21114	Uncharacterized protein, isoform A. (2561 aa)
	DpseGA22138	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2641 aa)
	CycC	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...] (267 aa)
	Q297P2	Uncharacterized protein, isoform B. (557 aa)
	Dpse_Scr	Antp family, other. (426 aa)
	Q293V0	Mediator of RNA polymerase II transcription subunit 17. (642 aa)
	B5E068	Uncharacterized protein, isoform A. (1785 aa)
	DpseGA28311	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (453 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CycC	DpseGA21114	Q29AI1	Q2LZZ5	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	Uncharacterized protein, isoform A.	0.988
CycC	DpseGA22138	Q29AI1	Q2M159	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.979
CycC	DpseGA28311	Q29AI1	B5DRF0	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
CycC	Q293V0	Q29AI1	Q293V0	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	Mediator of RNA polymerase II transcription subunit 17.	0.957
DpseGA21114	CycC	Q2LZZ5	Q29AI1	Uncharacterized protein, isoform A.	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	0.988
DpseGA21114	DpseGA22138	Q2LZZ5	Q2M159	Uncharacterized protein, isoform A.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.991
DpseGA21114	DpseGA28311	Q2LZZ5	B5DRF0	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.980
DpseGA21114	Q293V0	Q2LZZ5	Q293V0	Uncharacterized protein, isoform A.	Mediator of RNA polymerase II transcription subunit 17.	0.972
DpseGA22138	CycC	Q2M159	Q29AI1	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	0.979
DpseGA22138	DpseGA21114	Q2M159	Q2LZZ5	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein, isoform A.	0.991
DpseGA22138	DpseGA28311	Q2M159	B5DRF0	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.976
DpseGA22138	Q293V0	Q2M159	Q293V0	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 17.	0.944
DpseGA28311	CycC	B5DRF0	Q29AI1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	0.998
DpseGA28311	DpseGA21114	B5DRF0	Q2LZZ5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein, isoform A.	0.980
DpseGA28311	DpseGA22138	B5DRF0	Q2M159	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.976
DpseGA28311	Q293V0	B5DRF0	Q293V0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 17.	0.983
Q293V0	CycC	Q293V0	Q29AI1	Mediator of RNA polymerase II transcription subunit 17.	Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase Cdk8 that phosphoryla [...]	0.957
Q293V0	DpseGA21114	Q293V0	Q2LZZ5	Mediator of RNA polymerase II transcription subunit 17.	Uncharacterized protein, isoform A.	0.972
Q293V0	DpseGA22138	Q293V0	Q2M159	Mediator of RNA polymerase II transcription subunit 17.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.944
Q293V0	DpseGA28311	Q293V0	B5DRF0	Mediator of RNA polymerase II transcription subunit 17.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.983