(20 nodes) Negative regulation of hemocyte differentiation network (Drosophila pseudoobscura)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	DpseGA19197	Uncharacterized protein. (354 aa)
	A0A0R3NG32	Uncharacterized protein. (1222 aa)
	A0A0R3NJF4	Uncharacterized protein, isoform A. (2563 aa)
	DpseGA19047	Uncharacterized protein, isoform C. (503 aa)
	DpseGA28528	Uncharacterized protein. (2709 aa)
	DpseGA26902	UBIQUITIN_CONJUGAT_2 domain-containing protein. (178 aa)
	small-wing	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1250 aa)
	DpseGA28721	MNNL domain-containing protein. (102 aa)
	B5DWT5	Uncharacterized protein. (1390 aa)
	I5APP4	Uncharacterized protein, isoform C. (963 aa)
	Q293L2	Uncharacterized protein, isoform A. (751 aa)
	Q293U1	Uncharacterized protein. (617 aa)
	Q294I0	Uncharacterized protein, isoform A. (765 aa)
	Q296C9	COP9 signalosome complex subunit 5. (327 aa)
	DpseGA15455	Uncharacterized protein. (1276 aa)
	DpseGA15704	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	DpseGA11505	GCM domain-containing protein. (521 aa)
	DpseGA17734	Uncharacterized protein, isoform A. (617 aa)
	DpseGA19176	ANK_REP_REGION domain-containing protein. (532 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NG32	B5DWT5	A0A0R3NG32	B5DWT5	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A0R3NG32	DpseGA28528	A0A0R3NG32	B5DM97	Uncharacterized protein.	Uncharacterized protein.	0.979
A0A0R3NG32	DpseGA28721	A0A0R3NG32	B5DUT0	Uncharacterized protein.	MNNL domain-containing protein.	0.430
B5DWT5	A0A0R3NG32	B5DWT5	A0A0R3NG32	Uncharacterized protein.	Uncharacterized protein.	0.900
B5DWT5	DpseGA28528	B5DWT5	B5DM97	Uncharacterized protein.	Uncharacterized protein.	0.979
DpseGA11505	Q293U1	Q29NA4	Q293U1	GCM domain-containing protein.	Uncharacterized protein.	0.549
DpseGA15704	DpseGA19176	Q29N51	Q29NM7	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	ANK_REP_REGION domain-containing protein.	0.503
DpseGA15704	DpseGA26902	Q29N51	B5DMF4	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.906
DpseGA19047	DpseGA28528	A0A0R3NW51	B5DM97	Uncharacterized protein, isoform C.	Uncharacterized protein.	0.436
DpseGA19047	small-wing	A0A0R3NW51	B5DNH4	Uncharacterized protein, isoform C.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.920
DpseGA19176	DpseGA15704	Q29NM7	Q29N51	ANK_REP_REGION domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.503
DpseGA19176	DpseGA26902	Q29NM7	B5DMF4	ANK_REP_REGION domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.480
DpseGA26902	DpseGA15704	B5DMF4	Q29N51	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.906
DpseGA26902	DpseGA19176	B5DMF4	Q29NM7	UBIQUITIN_CONJUGAT_2 domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.480
DpseGA28528	A0A0R3NG32	B5DM97	A0A0R3NG32	Uncharacterized protein.	Uncharacterized protein.	0.979
DpseGA28528	B5DWT5	B5DM97	B5DWT5	Uncharacterized protein.	Uncharacterized protein.	0.979
DpseGA28528	DpseGA19047	B5DM97	A0A0R3NW51	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.436
DpseGA28528	DpseGA28721	B5DM97	B5DUT0	Uncharacterized protein.	MNNL domain-containing protein.	0.802
DpseGA28528	wg	B5DM97	Q29N82	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.702
DpseGA28721	A0A0R3NG32	B5DUT0	A0A0R3NG32	MNNL domain-containing protein.	Uncharacterized protein.	0.430