(50 nodes) Positive regulation of translation network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q29BK7	Diphthine methyl ester synthase. (281 aa)
	B5E0Q9	Polyadenylate-binding protein-interacting protein 1. (618 aa)
	B5DWJ1	Uncharacterized protein. (1502 aa)
	DpseGA24006	Uncharacterized protein. (300 aa)
	DpseGA22253	RNA_pol_Rpb1_5 domain-containing protein. (342 aa)
	DpseGA28708	Uncharacterized protein. (155 aa)
	I5AP84	Uncharacterized protein. (440 aa)
	I5APJ0	Uncharacterized protein, isoform G. (1533 aa)
	DpseGA21193	Uncharacterized protein. (352 aa)
	I7M5V3	Cellular nucleic acid-binding protein. (159 aa)
	Q28WW6	Uncharacterized protein. (296 aa)
	Q28YR5	Mitochondrial ribonuclease P protein 1. (447 aa)
	Q28YS3	Uncharacterized protein, isoform B. (1315 aa)
	Q28YU8	Uncharacterized protein. (744 aa)
	Q28ZZ7	Translation initiation factor 5A. (159 aa)
	Q290G0	Uncharacterized protein. (763 aa)
	Q290N0	Uncharacterized protein, isoform A. (640 aa)
	DpseGA26966	Uncharacterized protein, isoform A. (242 aa)
	DpseGA28855	Uncharacterized protein, isoform A. (605 aa)
	DpseGA28909	Tudor domain-containing protein. (177 aa)
	DpseGA22815	Translation factor waclaw, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (707 aa)
	DpseGA28966	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (219 aa)
	DpseGA28923	Uncharacterized protein. (226 aa)
	DpseGA11040	Uncharacterized protein, isoform D. (1635 aa)
	DpseGA18482	Uncharacterized protein, isoform C. (2013 aa)
	DpseGA18412	RRM domain-containing protein. (247 aa)
	DpseGA15540	Uncharacterized protein, isoform D. (786 aa)
	A0A0R3NLP3	Fragile X mental retardation protein. (702 aa)
	A0A0R3NEW8	Heterogeneous nuclear ribonucleoprotein A1/A3. (371 aa)
	Q292Q8	Regulator of nonsense transcripts 3. (514 aa)
	Q292R3	Small subunit ribosomal protein S27. (408 aa)
	DpseGA27654	Uncharacterized protein. (173 aa)
	Q295A4	Exonuclease 3'-5' domain-containing protein 2. (578 aa)
	Q296G6	Ras homolog enriched in brain. (182 aa)
	Q29AY5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1112 aa)
	DpseGA14391	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (699 aa)
	Mterf3	Uncharacterized protein. (351 aa)
	DpseGA28351	Uncharacterized protein, isoform A; Belongs to the universal ribosomal protein uS4 family. (195 aa)
	DpseGA18535	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (347 aa)
	DpseGA24628	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (234 aa)
	DpseGA14282	Uncharacterized protein. (924 aa)
	DpseGA10994	Protein kinase domain-containing protein. (287 aa)
	DpseGA11139	DUF155 domain-containing protein. (426 aa)
	DpseGA10287	Uncharacterized protein. (421 aa)
	DpseGA17737	Uncharacterized protein. (458 aa)
	DpseGA20176	JmjC domain-containing protein. (429 aa)
	DpseGA17798	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
	DpseGA12062	Uncharacterized protein, isoform A. (513 aa)
	DpseGA21647	Uncharacterized protein; Belongs to the DEAD box helicase family. (518 aa)
	DpseGA19382	Uncharacterized protein, isoform A; Belongs to the argonaute family. (851 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NEW8	DpseGA27654	A0A0R3NEW8	Q294T7	Heterogeneous nuclear ribonucleoprotein A1/A3.	Uncharacterized protein.	0.468
A0A0R3NEW8	Q290N0	A0A0R3NEW8	Q290N0	Heterogeneous nuclear ribonucleoprotein A1/A3.	Uncharacterized protein, isoform A.	0.438
A0A0R3NLP3	Q290N0	A0A0R3NLP3	Q290N0	Fragile X mental retardation protein.	Uncharacterized protein, isoform A.	0.428
B5DWJ1	B5E0Q9	B5DWJ1	B5E0Q9	Uncharacterized protein.	Polyadenylate-binding protein-interacting protein 1.	0.485
B5DWJ1	DpseGA28708	B5DWJ1	B5DTI3	Uncharacterized protein.	Uncharacterized protein.	0.433
B5DWJ1	I5APJ0	B5DWJ1	I5APJ0	Uncharacterized protein.	Uncharacterized protein, isoform G.	0.433
B5DWJ1	Q290N0	B5DWJ1	Q290N0	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.806
B5E0Q9	B5DWJ1	B5E0Q9	B5DWJ1	Polyadenylate-binding protein-interacting protein 1.	Uncharacterized protein.	0.485
B5E0Q9	DpseGA24628	B5E0Q9	Q29FK2	Polyadenylate-binding protein-interacting protein 1.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.718
B5E0Q9	DpseGA28966	B5E0Q9	B5DJG9	Polyadenylate-binding protein-interacting protein 1.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.718
B5E0Q9	Q290N0	B5E0Q9	Q290N0	Polyadenylate-binding protein-interacting protein 1.	Uncharacterized protein, isoform A.	0.990
DpseGA10287	Q290N0	Q29JX9	Q290N0	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.440
DpseGA11040	Q290N0	A0A0R3P6A9	Q290N0	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform A.	0.645
DpseGA12062	DpseGA15540	Q29ND8	A0A0R3NS94	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform D.	0.431
DpseGA14282	DpseGA22815	Q29IE7	B5DKL9	Uncharacterized protein.	Translation factor waclaw, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	0.472
DpseGA14282	DpseGA28351	Q29IE7	Q29EE2	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the universal ribosomal protein uS4 family.	0.638
DpseGA14282	I5AP84	Q29IE7	I5AP84	Uncharacterized protein.	Uncharacterized protein.	0.638
DpseGA14282	Q28ZZ7	Q29IE7	Q28ZZ7	Uncharacterized protein.	Translation initiation factor 5A.	0.619
DpseGA14391	DpseGA22253	Q29CI9	B5DTL9	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA_pol_Rpb1_5 domain-containing protein.	0.993
DpseGA14391	DpseGA22815	Q29CI9	B5DKL9	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Translation factor waclaw, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	0.624