(41 nodes) Positive regulation of cell size network (Drosophila pseudoobscura)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA28732	Uncharacterized protein. (207 aa)
	DpseGA12523	Uncharacterized protein, isoform E. (694 aa)
	DpseGA20908	Receptor protein-tyrosine kinase. (1649 aa)
	DpseGA32035	Protein kinase domain-containing protein. (157 aa)
	DpseGA19056	IRS-type PTB domain-containing protein. (272 aa)
	DpseGA32390	Raptor_N domain-containing protein. (1683 aa)
	DpseGA18654	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family. (2501 aa)
	DpseGA15916	Uncharacterized protein, isoform B; Belongs to the protein kinase superfamily. (384 aa)
	DpseGA28399	Uncharacterized protein, isoform D. (915 aa)
	A0A158SUH3	Uncharacterized protein. (392 aa)
	DpseGA27714	Nipped-B protein. (717 aa)
	DpseGA28770	Uncharacterized protein. (1618 aa)
	DpseGA23412	Uncharacterized protein, isoform A; Belongs to the fatty acid desaturase type 1 family. (379 aa)
	B5DVF9	Synaptotagmin-like protein. (4047 aa)
	B5DVL2	Uncharacterized protein. (370 aa)
	B5DYR5	Insulin-like growth factor 1 receptor. (2293 aa)
	N6W5Y1	annotation not available (1271 aa)
	Q28ZT1	Growth factor receptor-binding protein 2. (211 aa)
	Q290Y1	Uncharacterized protein. (354 aa)
	Tctp	Translationally-controlled tumor protein homolog; Involved in calcium binding and microtubule stabilization. Belongs to the TCTP family. (172 aa)
	Q294Q9	Serine/threonine kinase 16. (318 aa)
	Q294V1	RAC serine/threonine-protein kinase. (530 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	Q296F4	Kinase suppressor of Ras 2. (1012 aa)
	Q296G6	Ras homolog enriched in brain. (182 aa)
	Q298J6	Uncharacterized protein. (366 aa)
	Q299W4	Mitogen-activated protein kinase kinase kinase 4. (1574 aa)
	Q29AY5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1112 aa)
	Dpse_Desat1	Stearoyl-CoA desaturase (Delta-9 desaturase). (383 aa)
	Q29BB7	Eukaryotic translation initiation factor 2-alpha kinase 4. (1593 aa)
	DpseGA10383	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
	DpseGA20757	Uncharacterized protein. (1964 aa)
	DpseGA11504	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
	DpseGA10565	BHLH domain-containing protein. (734 aa)
	DpseGA20320	Mitogen-activated protein kinase. (365 aa)
	DpseGA20081	Uncharacterized protein, isoform A. (871 aa)
	DpseGA12522	Uncharacterized protein. (362 aa)
	DpseGA18860	Protein kinase domain-containing protein. (490 aa)
	DpseGA16888	Uncharacterized protein, isoform A. (572 aa)
	DpseGA11778	Uncharacterized protein. (1357 aa)
	DpseGA19640	Uncharacterized protein. (2152 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A158SUH3	DpseGA19056	A0A158SUH3	A0A0R3NWK0	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.478
A0A158SUH3	DpseGA28399	A0A158SUH3	A0A0R3P909	Uncharacterized protein.	Uncharacterized protein, isoform D.	0.591
A0A158SUH3	Q28ZT1	A0A158SUH3	Q28ZT1	Uncharacterized protein.	Growth factor receptor-binding protein 2.	0.967
A0A158SUH3	Q296F4	A0A158SUH3	Q296F4	Uncharacterized protein.	Kinase suppressor of Ras 2.	0.400
A0A158SUH3	Q296G6	A0A158SUH3	Q296G6	Uncharacterized protein.	Ras homolog enriched in brain.	0.415
A0A158SUH3	Q29AY5	A0A158SUH3	Q29AY5	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.657
A0A158SUH3	Ras85D	A0A158SUH3	Q295X7	Uncharacterized protein.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.653
B5DVL2	DpseGA10383	B5DVL2	Q29E52	Uncharacterized protein.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.562
B5DVL2	DpseGA11504	B5DVL2	Q29IB7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.990
B5DVL2	DpseGA15916	B5DVL2	A0A0R3P205	Uncharacterized protein.	Uncharacterized protein, isoform B; Belongs to the protein kinase superfamily.	0.912
B5DVL2	DpseGA20320	B5DVL2	Q29K65	Uncharacterized protein.	Mitogen-activated protein kinase.	0.902
B5DVL2	DpseGA28399	B5DVL2	A0A0R3P909	Uncharacterized protein.	Uncharacterized protein, isoform D.	0.534
B5DVL2	Q28ZT1	B5DVL2	Q28ZT1	Uncharacterized protein.	Growth factor receptor-binding protein 2.	0.462
B5DVL2	Q294V1	B5DVL2	Q294V1	Uncharacterized protein.	RAC serine/threonine-protein kinase.	0.417
B5DVL2	Q296F4	B5DVL2	Q296F4	Uncharacterized protein.	Kinase suppressor of Ras 2.	0.588
B5DVL2	Q298J6	B5DVL2	Q298J6	Uncharacterized protein.	Uncharacterized protein.	0.902
B5DVL2	Q299W4	B5DVL2	Q299W4	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 4.	0.520
B5DVL2	Ras85D	B5DVL2	Q295X7	Uncharacterized protein.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.425
B5DYR5	DpseGA10383	B5DYR5	Q29E52	Insulin-like growth factor 1 receptor.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.538
B5DYR5	DpseGA18654	B5DYR5	A0A0R3P0E1	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	0.510