STRINGSTRING
DpseGA18860 DpseGA18860 A0A0R3NKT4 A0A0R3NKT4 A0A0R3NMQ2 A0A0R3NMQ2 A0A0R3NPC7 A0A0R3NPC7 A0A0R3NPJ5 A0A0R3NPJ5 A0A0R3NSK5 A0A0R3NSK5 A0A0R3NT42 A0A0R3NT42 DpseGA10622 DpseGA10622 A0A0R3NWW2 A0A0R3NWW2 DpseGA30839 DpseGA30839 DpseGA28223 DpseGA28223 DpseGA28240 DpseGA28240 DpseGA30819 DpseGA30819 DpseGA28236 DpseGA28236 DpseGA32364 DpseGA32364 DpseGA25468 DpseGA25468 DpseGA25043 DpseGA25043 DpseGA26112 DpseGA26112 DpseGA22841 DpseGA22841 DpseGA22734 DpseGA22734 DpseGA23017 DpseGA23017 DpseGA22660 DpseGA22660 DpseGA22657 DpseGA22657 DpseGA22629 DpseGA22629 DpseGA28318 DpseGA28318 DpseGA28600 DpseGA28600 DpseGA28237 DpseGA28237 DpseGA29186 DpseGA29186 DpseGA29174 DpseGA29174 B5DX68 B5DX68 B5DXL4 B5DXL4 B5DXM1 B5DXM1 B5DY47 B5DY47 B5DY77 B5DY77 B5DZC0 B5DZC0 B5DZQ9 B5DZQ9 B5E068 B5E068 B5E0C3 B5E0C3 B5E1L5 B5E1L5 DpseGA30009 DpseGA30009 I5AN79 I5AN79 I5APZ7 I5APZ7 Q28WY5 Q28WY5 Q28X32 Q28X32 Q28XB2 Q28XB2 Q28XG8 Q28XG8 Q28XI0 Q28XI0 Q28XJ7 Q28XJ7 Q28YB0 Q28YB0 Q28YH6 Q28YH6 Q28YK7 Q28YK7 Q28YY0 Q28YY0 Q290F5 Q290F5 Q290P0 Q290P0 Q291A6 Q291A6 Q291L0 Q291L0 Tango7 Tango7 Q293S2 Q293S2 Q295L9 Q295L9 Q295Z5 Q295Z5 Q297T5 Q297T5 Fadd Fadd HtrA2 HtrA2 Q298D4 Q298D4 Q298J2 Q298J2 Q298K3 Q298K3 Q298N1 Q298N1 Q298R1 Q298R1 Q299D0 Q299D0 Q299G9 Q299G9 Q29A43 Q29A43 Q29C79 Q29C79 Q29CD4 Q29CD4 DpseGA19346 DpseGA19346 DpseGA22147 DpseGA22147 DpseGA11383 DpseGA11383 DpseGA11384 DpseGA11384 DpseGA14260 DpseGA14260 DpseGA15568 DpseGA15568 DpseGA13438 DpseGA13438 DpseGA12261 DpseGA12261 DpseGA17461 DpseGA17461 DpseGA15443 DpseGA15443 DpseGA13327 DpseGA13327 DpseGA14510 DpseGA14510 Dredd Dredd DpseGA15327 DpseGA15327 DpseGA14216 DpseGA14216 DpseGA15193 DpseGA15193 DpseGA13118 DpseGA13118 DpseGA14020 DpseGA14020 DpseGA10925 DpseGA10925 DpseGA16511 DpseGA16511 poe poe DpseGA15402 DpseGA15402 DpseGA21701 DpseGA21701 DpseGA20111 DpseGA20111 DpseGA21369 DpseGA21369 DpseGA12159 DpseGA12159 DpseGA14714 DpseGA14714 DpseGA17928 DpseGA17928 DpseGA17967 DpseGA17967 DpseGA18145 DpseGA18145 DpseGA18074 DpseGA18074 DpseGA21637 DpseGA21637 DpseGA13508 DpseGA13508 DpseGA18734 DpseGA18734 DpseGA16526 DpseGA16526 DpseGA21521 DpseGA21521 DpseGA10370 DpseGA10370 DpseGA18104 DpseGA18104 DpseGA18123 DpseGA18123 DpseGA18676 DpseGA18676 DpseGA19461 DpseGA19461 DpseGA11781 DpseGA11781 DpseGA11583 DpseGA11583 DpseGA20817 DpseGA20817 DpseGA20215 DpseGA20215 GA22148 GA22148
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DpseGA18860Protein kinase domain-containing protein. (490 aa)
A0A0R3NKT4Uncharacterized protein, isoform E. (646 aa)
A0A0R3NMQ2annotation not available (431 aa)
A0A0R3NPC7Uncharacterized protein, isoform A. (114 aa)
A0A0R3NPJ5Succinyl-CoA synthetase beta subunit. (504 aa)
A0A0R3NSK5Transitional endoplasmic reticulum ATPase. (865 aa)
A0A0R3NT42Cell division cycle 20-like protein 1, cofactor of APC complex. (459 aa)
DpseGA10622Uncharacterized protein, isoform B; Belongs to the protein kinase superfamily. (482 aa)
A0A0R3NWW2Uncharacterized protein, isoform A. (558 aa)
DpseGA30839Uncharacterized protein. (560 aa)
DpseGA28223Uncharacterized protein, isoform B. (434 aa)
DpseGA28240Uncharacterized protein, isoform B. (522 aa)
DpseGA30819Uncharacterized protein. (219 aa)
DpseGA28236Uncharacterized protein. (117 aa)
DpseGA32364Uncharacterized protein. (123 aa)
DpseGA25468Uncharacterized protein. (263 aa)
DpseGA25043Uncharacterized protein. (202 aa)
DpseGA26112Uncharacterized protein. (205 aa)
DpseGA22841RING-type domain-containing protein. (112 aa)
DpseGA22734Uncharacterized protein. (319 aa)
DpseGA23017RING-type domain-containing protein. (150 aa)
DpseGA22660Uncharacterized protein, isoform H. (880 aa)
DpseGA22657RBR-type E3 ubiquitin transferase. (503 aa)
DpseGA22629RING-type domain-containing protein. (217 aa)
DpseGA28318Uncharacterized protein. (209 aa)
DpseGA28600RING-type domain-containing protein. (229 aa)
DpseGA28237Uncharacterized protein. (307 aa)
DpseGA29186WD_REPEATS_REGION domain-containing protein. (514 aa)
DpseGA29174Uncharacterized protein. (432 aa)
B5DX68F-box and WD-40 domain protein 1/11. (590 aa)
B5DXL4Uncharacterized protein. (916 aa)
B5DXM126S proteasome regulatory subunit T6. (408 aa)
B5DY47Uncharacterized protein. (273 aa)
B5DY77Uncharacterized protein. (118 aa)
B5DZC0Uncharacterized protein. (371 aa)
B5DZQ9Uncharacterized protein. (101 aa)
B5E068Uncharacterized protein, isoform A. (1785 aa)
B5E0C3Uncharacterized protein. (102 aa)
B5E1L5Uncharacterized protein. (510 aa)
DpseGA30009BTB domain-containing protein. (779 aa)
I5AN79Uncharacterized protein. (731 aa)
I5APZ726S proteasome regulatory subunit T1. (433 aa)
Q28WY5Uncharacterized protein. (210 aa)
Q28X32E3 ubiquitin-protein transferase RMND5. (437 aa)
Q28XB2Proteasome inhibitor subunit 1 (PI31). (270 aa)
Q28XG8Uncharacterized protein, isoform A. (974 aa)
Q28XI0Ran-binding protein 9/10. (1078 aa)
Q28XJ7E3 ubiquitin-protein ligase RNF144. (1148 aa)
Q28YB0Uncharacterized protein. (774 aa)
Q28YH6Uncharacterized protein, isoform A. (854 aa)
Q28YK7Ribonucleoside-diphosphate reductase subunit M2. (391 aa)
Q28YY0F-box and leucine-rich repeat protein 6. (713 aa)
Q290F5Apoptotic protease-activating factor. (1489 aa)
Q290P0Serine/threonine kinase 3. (665 aa)
Q291A6E3 ubiquitin-protein ligase SH3RF. (858 aa)
Q291L0Uncharacterized protein. (613 aa)
Tango7Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (387 aa)
Q293S2Uncharacterized protein. (436 aa)
Q295L9Uncharacterized protein. (1526 aa)
Q295Z5Ubiquitin-conjugating enzyme E2 A. (151 aa)
Q297T5Uncharacterized protein. (348 aa)
FaddFas-associated death domain protein; Component of the IMD signaling pathway and is required for the host defense against Gram-negative bacteria. Interacts with Dredd, promotes cleavage of Dredd and is necessary and sufficient for enhancing Dredd-induced apoptosis (By similarity). (241 aa)
HtrA2Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Can antagonize antiapoptotic activity of th by directly inducing the degradation of th (By similarity); Belongs to the peptidase S1C family. (427 aa)
Q298D4Uncharacterized protein. (492 aa)
Q298J2Adenomatosis polyposis coli protein. (1088 aa)
Q298K3Uncharacterized protein. (688 aa)
Q298N126S proteasome regulatory subunit T2. (439 aa)
Q298R1E3 ubiquitin-protein ligase synoviolin. (662 aa)
Q299D026S proteasome regulatory subunit T5. (428 aa)
Q299G926S proteasome regulatory subunit T3. (401 aa)
Q29A43Interleukin-1 receptor-associated kinase 1. (500 aa)
Q29C79Uncharacterized protein, isoform A. (762 aa)
Q29CD4Uncharacterized protein, isoform D. (439 aa)
DpseGA19346Uncharacterized protein. (576 aa)
DpseGA22147E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (314 aa)
DpseGA11383Ubiquitin carboxyl-terminal hydrolase. (829 aa)
DpseGA11384Uncharacterized protein, isoform A. (791 aa)
DpseGA14260RING-type domain-containing protein. (123 aa)
DpseGA15568Uncharacterized protein, isoform A. (478 aa)
DpseGA13438Uncharacterized protein. (248 aa)
DpseGA12261Uncharacterized protein. (154 aa)
DpseGA17461AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa)
DpseGA15443Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (390 aa)
DpseGA13327AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa)
DpseGA14510Uncharacterized protein, isoform A. (356 aa)
DreddCaspase-8 subunit p10; Effector of the programmed cell death (PCD) activators rpr, grim and W. May play an apoptotic role in the germline as well as soma. Role in immune response, required to resist Gram-negative bacterial infections by regulating DptA. Fadd interacts with Dredd, Fadd promotes cleavage of Dredd and is necessary and sufficient for enhancing Dredd- induced apoptosis; Belongs to the peptidase C14A family. (511 aa)
DpseGA15327Uncharacterized protein, isoform B; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
DpseGA14216AAA domain-containing protein; Belongs to the AAA ATPase family. (413 aa)
DpseGA15193Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (337 aa)
DpseGA13118Ubiquitin carboxyl-terminal hydrolase. (872 aa)
DpseGA14020Uncharacterized protein. (308 aa)
DpseGA10925Uncharacterized protein, isoform A. (488 aa)
DpseGA16511Uncharacterized protein, isoform C; Belongs to the cullin family. (902 aa)
poeProtein purity of essence; Has a role in growth of the perineurial glial layer of the larval peripheral nerve. May have a role in male fertility and eye development or function. May bind calmodulin (By similarity). (5381 aa)
DpseGA15402Protein kinase domain-containing protein. (719 aa)
DpseGA21701Uncharacterized protein. (133 aa)
DpseGA20111Uncharacterized protein, isoform B. (318 aa)
DpseGA21369Uncharacterized protein. (403 aa)
DpseGA12159Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
DpseGA14714Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
DpseGA17928Uncharacterized protein. (694 aa)
DpseGA17967FERM domain-containing protein. (1515 aa)
DpseGA18145Uncharacterized protein, isoform C; Belongs to the protein kinase superfamily. (353 aa)
DpseGA18074WD_REPEATS_REGION domain-containing protein. (532 aa)
DpseGA21637Uncharacterized protein. (700 aa)
DpseGA13508Uncharacterized protein, isoform A; Belongs to the cullin family. (756 aa)
DpseGA18734Uncharacterized protein. (289 aa)
DpseGA16526DDA1 domain-containing protein. (106 aa)
DpseGA21521Uncharacterized protein, isoform A; Belongs to the DEAD box helicase family. (404 aa)
DpseGA10370E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (485 aa)
DpseGA18104Uncharacterized protein. (72 aa)
DpseGA18123Uncharacterized protein. (150 aa)
DpseGA18676Uncharacterized protein. (405 aa)
DpseGA19461Uncharacterized protein. (313 aa)
DpseGA11781Uncharacterized protein, isoform A. (243 aa)
DpseGA11583RBR-type E3 ubiquitin transferase. (528 aa)
DpseGA20817Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
DpseGA20215AAA domain-containing protein; Belongs to the AAA ATPase family. (407 aa)
GA22148Coiled-coil domain-containing protein 22 homolog; Belongs to the CCDC22 family. (553 aa)
Your Current Organism:
Drosophila pseudoobscura
NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura
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