(35 nodes) Regulation of developmental pigmentation network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q298J6	Uncharacterized protein. (366 aa)
	A0A0R3NGF8	Uncharacterized protein. (142 aa)
	A0A0R3NNC1	Uncharacterized protein, isoform A. (263 aa)
	A0A0R3NPB8	Uncharacterized protein. (147 aa)
	DpseGA31562	Uncharacterized protein. (235 aa)
	DpseGA18232	Uncharacterized protein, isoform B. (718 aa)
	DpseGA30601	Uncharacterized protein. (113 aa)
	DpseGA28563	Uncharacterized protein, isoform C. (788 aa)
	A0A158SUH8	Uncharacterized protein. (164 aa)
	DpseGA25950	Uncharacterized protein. (1279 aa)
	DpseGA23083	Uncharacterized protein. (365 aa)
	DpseGA28799	Uncharacterized protein, isoform B. (134 aa)
	DpseGA23504	Uncharacterized protein. (264 aa)
	DpseGA23169	HTH psq-type domain-containing protein. (515 aa)
	B5DVL2	Uncharacterized protein. (370 aa)
	B5DYW4	Biogenesis of lysosome-related organelles complex 1 subunit 5. (155 aa)
	B5E0S0	Uncharacterized protein, isoform A. (288 aa)
	I5ANM9	Uncharacterized protein, isoform A. (785 aa)
	Q28ZT5	Low density lipoprotein receptor-related protein 5/6. (1687 aa)
	Dpse_Pk92B	Mitogen-activated protein kinase kinase kinase 5. (1357 aa)
	Q297N4	Mitogen-activated protein kinase kinase 4. (428 aa)
	Q297P2	Uncharacterized protein, isoform B. (557 aa)
	Q298N7	GTP-binding protein SAR1. (193 aa)
	Q29B08	Uncharacterized protein. (879 aa)
	Ddc	Ddc, isoform A. (515 aa)
	DpseGA10085	BH4_AAA_HYDROXYL_2 domain-containing protein. (575 aa)
	DpseGA14904	Uncharacterized protein. (618 aa)
	DpseGA11504	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
	DpseGA11430	Uncharacterized protein. (4664 aa)
	DpseGA14570	Non-specific serine/threonine protein kinase. (960 aa)
	DpseGA20320	Mitogen-activated protein kinase. (365 aa)
	DpseGA15026	Uncharacterized protein. (847 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	DpseGA10370	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (485 aa)
	y	Protein yellow; Controls the pigmentation pattern of the adult cuticle and larval mouth parts; Belongs to the major royal jelly protein family. (560 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NGF8	DpseGA14904	A0A0R3NGF8	Q29H20	Uncharacterized protein.	Uncharacterized protein.	0.520
A0A0R3NNC1	DpseGA14904	A0A0R3NNC1	Q29H20	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.520
A0A0R3NPB8	DpseGA14904	A0A0R3NPB8	Q29H20	Uncharacterized protein.	Uncharacterized protein.	0.520
A0A158SUH8	DpseGA14904	A0A158SUH8	Q29H20	Uncharacterized protein.	Uncharacterized protein.	0.508
A0A158SUH8	DpseGA23504	A0A158SUH8	B5DNL0	Uncharacterized protein.	Uncharacterized protein.	0.462
B5DVL2	DpseGA11504	B5DVL2	Q29IB7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.990
B5DVL2	DpseGA14570	B5DVL2	Q29JG0	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.678
B5DVL2	DpseGA20320	B5DVL2	Q29K65	Uncharacterized protein.	Mitogen-activated protein kinase.	0.902
B5DVL2	Q298J6	B5DVL2	Q298J6	Uncharacterized protein.	Uncharacterized protein.	0.902
B5E0S0	DpseGA14904	B5E0S0	Q29H20	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.520
Ddc	DpseGA10085	Q29CL0	Q29DR7	Ddc, isoform A.	BH4_AAA_HYDROXYL_2 domain-containing protein.	0.955
Ddc	Q29B08	Q29CL0	Q29B08	Ddc, isoform A.	Uncharacterized protein.	0.453
DpseGA10085	Ddc	Q29DR7	Q29CL0	BH4_AAA_HYDROXYL_2 domain-containing protein.	Ddc, isoform A.	0.955
DpseGA10085	DpseGA10370	Q29DR7	Q2LYR0	BH4_AAA_HYDROXYL_2 domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.416
DpseGA10085	Q29B08	Q29DR7	Q29B08	BH4_AAA_HYDROXYL_2 domain-containing protein.	Uncharacterized protein.	0.646
DpseGA10370	DpseGA10085	Q2LYR0	Q29DR7	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	BH4_AAA_HYDROXYL_2 domain-containing protein.	0.416
DpseGA10370	DpseGA18232	Q2LYR0	A0A0R3P2K3	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Uncharacterized protein, isoform B.	0.999
DpseGA11430	DpseGA14904	Q29ID0	Q29H20	Uncharacterized protein.	Uncharacterized protein.	0.452
DpseGA11504	B5DVL2	Q29IB7	B5DVL2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.990
DpseGA11504	DpseGA20320	Q29IB7	Q29K65	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.990