(75 nodes) Multicellular organismal homeostasis network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rho	Rho; Belongs to the peptidase S54 family. (373 aa)
	A0A0R3NF67	Solute carrier family 39 (zinc transporter), member 13. (404 aa)
	A0A0R3NHI5	Uncharacterized protein, isoform A. (2503 aa)
	A0A0R3NI42	Uncharacterized protein, isoform D. (2255 aa)
	A0A0R3NJG6	Uncharacterized protein, isoform J. (1216 aa)
	A0A0R3NKT1	Phosphoinositide-3-kinase, regulatory subunit 4. (1353 aa)
	A0A0R3NKT4	Uncharacterized protein, isoform E. (646 aa)
	A0A0R3NMH5	Uncharacterized protein, isoform A. (641 aa)
	A0A0R3NP01	Uncharacterized protein, isoform A. (535 aa)
	DpseGA23031	Integrin beta; Belongs to the integrin beta chain family. (856 aa)
	DpseGA23034	Diacylglycerol kinase. (1499 aa)
	DpseGA19279	Uncharacterized protein, isoform B. (438 aa)
	DpseGA12508	Uncharacterized protein, isoform B; Belongs to the G-protein coupled receptor 2 family. (764 aa)
	DpseGA17564	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1095 aa)
	DpseGA11344	Uncharacterized protein, isoform B. (880 aa)
	DpseGA28476	Uncharacterized protein. (838 aa)
	DpseGA28528	Uncharacterized protein. (2709 aa)
	DpseGA22327	Uncharacterized protein. (382 aa)
	DpseGA27916	Uncharacterized protein, isoform A. (1215 aa)
	DpseGA27683	Uncharacterized protein. (209 aa)
	Dpse_Ama	Ama. (329 aa)
	B5E1G4	Uncharacterized protein, isoform A. (1517 aa)
	I5ANM7	Nicotinamide mononucleotide adenylyltransferase. (354 aa)
	I5ANS6	Sodium/potassium-transporting ATPase subunit alpha. (1041 aa)
	I5APB1	Uncharacterized protein, isoform C. (1114 aa)
	I5APP4	Uncharacterized protein, isoform C. (963 aa)
	N6W6F6	Uncharacterized protein, isoform D. (867 aa)
	Q28XD4	Uncharacterized protein. (323 aa)
	Q28XM9	Uncharacterized protein, isoform A. (1439 aa)
	Q28XT1	Uncharacterized protein. (686 aa)
	Q28Y34	Uncharacterized protein. (365 aa)
	Q28ZE7	Phosphatidylinositol 3-kinase. (966 aa)
	Q28ZZ9	Uncharacterized protein. (148 aa)
	Dpse_Atg9	Autophagy-related protein 9. (827 aa)
	Q292N5	ESCRT-II complex subunit VPS25. (174 aa)
	Q294C2	Serine-protein kinase ATM. (2771 aa)
	Q295G3	Uncharacterized protein, isoform B. (1156 aa)
	Q297M2	RB1-inducible coiled-coil protein 1. (1369 aa)
	Q297Q7	Uncharacterized protein, isoform A. (984 aa)
	Q298R4	Autophagy-related protein 13. (551 aa)
	Q299L5	Uncharacterized protein. (679 aa)
	Q299N9	Uncharacterized protein, isoform D. (523 aa)
	Q29AF9	Solute carrier family 25 (mitochondrial iron transporter), member 28/37. (388 aa)
	Q29C99	Transient receptor potential cation channel subfamily C member 4. (1251 aa)
	DpseGA19261	Arrestin_C domain-containing protein. (401 aa)
	DpseGA12750	Uncharacterized protein. (573 aa)
	DpseGA20071	Uncharacterized protein. (219 aa)
	DpseGA19890	Uncharacterized protein, isoform B. (2865 aa)
	DpseGA19283	Uncharacterized protein. (539 aa)
	DpseGA12831	Uncharacterized protein, isoform A. (1034 aa)
	DpseGA17546	Uncharacterized protein, isoform A. (174 aa)
	DpseGA22115	C2H2-type domain-containing protein. (565 aa)
	DpseGA12841	FERM domain-containing protein. (636 aa)
	DpseGA11419	Uncharacterized protein. (530 aa)
	DpseGA11481	Uncharacterized protein. (1960 aa)
	DpseGA21920	Uncharacterized protein, isoform A; Belongs to the integrin alpha chain family. (1368 aa)
	DpseGA14619	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1067 aa)
	DpseGA13629	Uncharacterized protein, isoform A. (3393 aa)
	DpseGA17987	Collagen IV NC1 domain-containing protein. (1784 aa)
	DpseGA13735	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (886 aa)
	DpseGA19076	Arrestin_C domain-containing protein. (363 aa)
	DpseGA15402	Protein kinase domain-containing protein. (719 aa)
	DpseGA14394	Rhomboid domain-containing protein. (252 aa)
	DpseGA16835	TIMELESS domain-containing protein. (1238 aa)
	DpseGA10441	Uncharacterized protein. (548 aa)
	DpseGA17967	FERM domain-containing protein. (1515 aa)
	DpseGA15455	Uncharacterized protein. (1276 aa)
	DpseGA15471	Uncharacterized protein. (153 aa)
	DpseGA18678	Uncharacterized protein, isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1498 aa)
	DpseGA19688	START domain-containing protein. (437 aa)
	DpseGA20425	Uncharacterized protein, isoform A. (327 aa)
	DpseGA14476	Uncharacterized protein, isoform A. (976 aa)
	DpseGA10675	Protein kinase domain-containing protein. (859 aa)
	DpseGA10447	Uncharacterized protein, isoform B. (662 aa)
	DpseGA19332	Uncharacterized protein. (939 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NHI5	DpseGA19688	A0A0R3NHI5	Q29P90	Uncharacterized protein, isoform A.	START domain-containing protein.	0.609
A0A0R3NHI5	DpseGA19890	A0A0R3NHI5	Q29FI8	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.601
A0A0R3NI42	B5E1G4	A0A0R3NI42	B5E1G4	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform A.	0.501
A0A0R3NI42	DpseGA11344	A0A0R3NI42	A0A0R3P3U6	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform B.	0.894
A0A0R3NI42	DpseGA17967	A0A0R3NI42	Q29N45	Uncharacterized protein, isoform D.	FERM domain-containing protein.	0.971
A0A0R3NI42	Q297Q7	A0A0R3NI42	Q297Q7	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform A.	0.514
A0A0R3NKT1	A0A0R3NMH5	A0A0R3NKT1	A0A0R3NMH5	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein, isoform A.	0.847
A0A0R3NKT1	DpseGA10675	A0A0R3NKT1	Q2LYW8	Phosphoinositide-3-kinase, regulatory subunit 4.	Protein kinase domain-containing protein.	0.993
A0A0R3NKT1	Dpse_Atg9	A0A0R3NKT1	Q291S1	Phosphoinositide-3-kinase, regulatory subunit 4.	Autophagy-related protein 9.	0.869
A0A0R3NKT1	Q28ZE7	A0A0R3NKT1	Q28ZE7	Phosphoinositide-3-kinase, regulatory subunit 4.	Phosphatidylinositol 3-kinase.	0.999
A0A0R3NKT1	Q297M2	A0A0R3NKT1	Q297M2	Phosphoinositide-3-kinase, regulatory subunit 4.	RB1-inducible coiled-coil protein 1.	0.863
A0A0R3NKT1	Q298R4	A0A0R3NKT1	Q298R4	Phosphoinositide-3-kinase, regulatory subunit 4.	Autophagy-related protein 13.	0.876
A0A0R3NKT4	Q294C2	A0A0R3NKT4	Q294C2	Uncharacterized protein, isoform E.	Serine-protein kinase ATM.	0.957
A0A0R3NMH5	A0A0R3NKT1	A0A0R3NMH5	A0A0R3NKT1	Uncharacterized protein, isoform A.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.847
A0A0R3NMH5	DpseGA10675	A0A0R3NMH5	Q2LYW8	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein.	0.928
A0A0R3NMH5	DpseGA20071	A0A0R3NMH5	Q29F84	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.718
A0A0R3NMH5	Dpse_Atg9	A0A0R3NMH5	Q291S1	Uncharacterized protein, isoform A.	Autophagy-related protein 9.	0.653
A0A0R3NMH5	Q28ZE7	A0A0R3NMH5	Q28ZE7	Uncharacterized protein, isoform A.	Phosphatidylinositol 3-kinase.	0.882
A0A0R3NMH5	Q297M2	A0A0R3NMH5	Q297M2	Uncharacterized protein, isoform A.	RB1-inducible coiled-coil protein 1.	0.985
A0A0R3NMH5	Q298R4	A0A0R3NMH5	Q298R4	Uncharacterized protein, isoform A.	Autophagy-related protein 13.	0.712