(35 nodes) Homeostasis of number of cells network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q29A57	Nuclear factor erythroid 2, invertebrate. (1409 aa)
	Q29AR9	Uncharacterized protein. (173 aa)
	Q29AY5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1112 aa)
	Q29AY6	Uncharacterized protein. (1096 aa)
	DpseGA20071	Uncharacterized protein. (219 aa)
	DpseGA19283	Uncharacterized protein. (539 aa)
	DpseGA12831	Uncharacterized protein, isoform A. (1034 aa)
	DpseGA17988	Uncharacterized protein, isoform A; Belongs to the heat shock protein 70 family. (656 aa)
	DpseGA21416	Uncharacterized protein, isoform A. (1374 aa)
	DpseGA10303	N-acetyltransferase domain-containing protein. (797 aa)
	DpseGA19920	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (506 aa)
	DpseGA21036	Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	Q298R1	E3 ubiquitin-protein ligase synoviolin. (662 aa)
	Q298J9	Uncharacterized protein, isoform A. (1107 aa)
	Madm	Nuclear receptor-binding protein homolog; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus. (663 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	Q294U1	Uncharacterized protein. (725 aa)
	Q28XN2	MAD, mothers against decapentaplegic interacting protein. (1352 aa)
	GA12348	OCIA domain-containing protein 1; Belongs to the OCIAD1 family. (260 aa)
	B5E1L5	Uncharacterized protein. (510 aa)
	B5DYR5	Insulin-like growth factor 1 receptor. (2293 aa)
	B5DVU9	Serine/threonine-protein phosphatase 2A regulatory subunit B'. (439 aa)
	DpseGA23613	Uncharacterized protein, isoform A; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	DpseGA22327	Uncharacterized protein. (382 aa)
	DpseGA28528	Uncharacterized protein. (2709 aa)
	DpseGA22607	Uncharacterized protein, isoform A. (1248 aa)
	DpseGA22797	PHD-type domain-containing protein. (495 aa)
	DpseGA25785	Uncharacterized protein. (1395 aa)
	DpseGA28654	Uncharacterized protein, isoform B. (1681 aa)
	DpseGA11336	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (245 aa)
	DpseGA28096	Uncharacterized protein, isoform B. (2051 aa)
	DpseGA20908	Receptor protein-tyrosine kinase. (1649 aa)
	A0A0R3NNZ3	Uncharacterized protein, isoform A. (1711 aa)
	A0A0R3NMH5	Uncharacterized protein, isoform A. (641 aa)
	A0A0R3NKT4	Uncharacterized protein, isoform E. (646 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NMH5	DpseGA20071	A0A0R3NMH5	Q29F84	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.718
A0A0R3NNZ3	DpseGA20908	A0A0R3NNZ3	A0A0R3NSX3	Uncharacterized protein, isoform A.	Receptor protein-tyrosine kinase.	0.516
A0A0R3NNZ3	Q298J9	A0A0R3NNZ3	Q298J9	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.478
A0A0R3NNZ3	Q29AY5	A0A0R3NNZ3	Q29AY5	Uncharacterized protein, isoform A.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.566
A0A0R3NNZ3	Ras85D	A0A0R3NNZ3	Q295X7	Uncharacterized protein, isoform A.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.777
B5DYR5	DpseGA28096	B5DYR5	A0A0R3NVE1	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform B.	0.428
B5DYR5	Q298J9	B5DYR5	Q298J9	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform A.	0.550
B5DYR5	Q29A57	B5DYR5	Q29A57	Insulin-like growth factor 1 receptor.	Nuclear factor erythroid 2, invertebrate.	0.516
B5DYR5	Q29AY5	B5DYR5	Q29AY5	Insulin-like growth factor 1 receptor.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.958
B5DYR5	Ras85D	B5DYR5	Q295X7	Insulin-like growth factor 1 receptor.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.923
B5E1L5	DpseGA17988	B5E1L5	Q29HE5	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the heat shock protein 70 family.	0.754
B5E1L5	Q298R1	B5E1L5	Q298R1	Uncharacterized protein.	E3 ubiquitin-protein ligase synoviolin.	0.582
B5E1L5	Q29A57	B5E1L5	Q29A57	Uncharacterized protein.	Nuclear factor erythroid 2, invertebrate.	0.543
DpseGA11336	DpseGA19920	A0A0R3P5V7	Q2M0D6	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.595
DpseGA17988	B5E1L5	Q29HE5	B5E1L5	Uncharacterized protein, isoform A; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.754
DpseGA17988	Q298J9	Q29HE5	Q298J9	Uncharacterized protein, isoform A; Belongs to the heat shock protein 70 family.	Uncharacterized protein, isoform A.	0.802
DpseGA17988	Q298R1	Q29HE5	Q298R1	Uncharacterized protein, isoform A; Belongs to the heat shock protein 70 family.	E3 ubiquitin-protein ligase synoviolin.	0.807
DpseGA19283	DpseGA22327	Q29G27	B5DNM4	Uncharacterized protein.	Uncharacterized protein.	0.912
DpseGA19920	DpseGA11336	Q2M0D6	A0A0R3P5V7	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.595
DpseGA20071	A0A0R3NMH5	Q29F84	A0A0R3NMH5	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.718