(82 nodes) Cell adhesion molecule binding network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA28161	Thioredoxin domain-containing protein. (149 aa)
	A0A0R3NGH2	annotation not available (155 aa)
	A0A0R3NGT6	Uncharacterized protein, isoform E. (689 aa)
	A0A0R3NH46	Uncharacterized protein, isoform A. (478 aa)
	A0A0R3NJD9	Uncharacterized protein, isoform G. (2610 aa)
	A0A0R3NJU0	annotation not available (968 aa)
	A0A0R3NK49	Uncharacterized protein, isoform A. (2130 aa)
	A0A0R3NLJ2	Uncharacterized protein, isoform B. (1081 aa)
	A0A0R3NP57	Uncharacterized protein, isoform B. (1145 aa)
	A0A0R3NQG1	Uncharacterized protein, isoform A. (1735 aa)
	Dpse_Dscam	Dscam, isoform B. (2049 aa)
	DpseGA13718	Uncharacterized protein, isoform B. (1616 aa)
	DpseGA14181	Uncharacterized protein, isoform B. (718 aa)
	A0A0R3NSA3	Uncharacterized protein, isoform A. (1592 aa)
	DpseGA19141	Uncharacterized protein, isoform D. (590 aa)
	DpseGA26093	Uncharacterized protein, isoform J; Cadherins are calcium-dependent cell adhesion proteins. (3120 aa)
	DpseGA16333	Uncharacterized protein, isoform B. (670 aa)
	A0A0R3NVE4	Cadherin EGF LAG seven-pass G-type receptor 1. (3626 aa)
	DpseGA23031	Integrin beta; Belongs to the integrin beta chain family. (856 aa)
	DpseGA27134	Uncharacterized protein, isoform B. (828 aa)
	DpseGA19049	Uncharacterized protein, isoform B. (1202 aa)
	DpseGA30789	Uncharacterized protein. (501 aa)
	DpseGA31615	Uncharacterized protein, isoform A. (285 aa)
	DpseGA17599	Uncharacterized protein, isoform D. (891 aa)
	DpseGA32194	Uncharacterized protein. (287 aa)
	DpseGA24633	Uncharacterized protein, isoform B. (1935 aa)
	DpseGA16918	Uncharacterized protein, isoform L. (2096 aa)
	DpseGA31408	Uncharacterized protein. (484 aa)
	DpseGA27700	Uncharacterized protein, isoform C. (2309 aa)
	DpseGA23806	Uncharacterized protein, isoform B. (1363 aa)
	DpseGA25719	Uncharacterized protein. (1045 aa)
	DpseGA26057	Uncharacterized protein, isoform A. (3586 aa)
	DpseGA23727	Thioredoxin domain-containing protein. (216 aa)
	DpseGA22393	Uncharacterized protein. (2021 aa)
	DpseGA23550	Uncharacterized protein. (522 aa)
	DpseGA24011	Uncharacterized protein. (545 aa)
	DpseGA23242	Uncharacterized protein. (2183 aa)
	B5DVU6	Uncharacterized protein. (216 aa)
	B5DXX3	Uncharacterized protein. (143 aa)
	B5DYP9	Uncharacterized protein, isoform A. (167 aa)
	B5DZC0	Uncharacterized protein. (371 aa)
	I5AP07	Uncharacterized protein, isoform J. (1331 aa)
	I5AP38	Uncharacterized protein, isoform B. (1602 aa)
	N6V903	annotation not available (1267 aa)
	N6WCC8	Uncharacterized protein, isoform D. (1575 aa)
	Q28XX4	Uncharacterized protein, isoform C. (849 aa)
	Q28ZM3	Uncharacterized protein, isoform A. (1236 aa)
	otk	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity). (1037 aa)
	Q290N6	Uncharacterized protein. (428 aa)
	Q290Z5	Uncharacterized protein. (485 aa)
	Q295F4	Uncharacterized protein. (1409 aa)
	Q295T4	Uncharacterized protein, isoform E. (892 aa)
	Q296A4	Uncharacterized protein, isoform A. (2113 aa)
	DpseGA16675	Uncharacterized protein, isoform A. (1924 aa)
	DpseGA21977	COesterase domain-containing protein. (845 aa)
	DpseGA19603	Uncharacterized protein, isoform A. (245 aa)
	DpseGA20549	Uncharacterized protein, isoform A. (711 aa)
	DpseGA19890	Uncharacterized protein, isoform B. (2865 aa)
	DpseGA14061	Uncharacterized protein, isoform A. (1309 aa)
	DpseGA18587	Uncharacterized protein, isoform B. (1301 aa)
	DpseGA17590	Uncharacterized protein, isoform B. (959 aa)
	DpseGA12841	FERM domain-containing protein. (636 aa)
	arm	Armadillo segment polarity protein; May associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis (By similarity). Belongs to the beta-catenin family. (832 aa)
	DpseGA21920	Uncharacterized protein, isoform A; Belongs to the integrin alpha chain family. (1368 aa)
	DpseGA14619	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1067 aa)
	DpseGA17219	Uncharacterized protein. (1194 aa)
	DpseGA20415	Uncharacterized protein, isoform B; Cadherins are calcium-dependent cell adhesion proteins. (1800 aa)
	DpseGA19109	Uncharacterized protein, isoform A. (628 aa)
	DpseGA17645	Uncharacterized protein, isoform A. (556 aa)
	DpseGA16466	Uncharacterized protein, isoform C. (1465 aa)
	DpseGA11750	Uncharacterized protein, isoform D. (1351 aa)
	DpseGA17999	J domain-containing protein. (355 aa)
	DpseGA16414	Uncharacterized protein. (285 aa)
	DpseGA16416	Uncharacterized protein. (1980 aa)
	DpseGA17399	Uncharacterized protein, isoform B. (5256 aa)
	DpseGA14581	Integrin beta; Belongs to the integrin beta chain family. (804 aa)
	DpseGA12952	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1248 aa)
	ck	Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high- duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction [...] (2168 aa)
	DpseGA10202	RING-type domain-containing protein. (433 aa)
	DpseGA13408	PH domain-containing protein. (711 aa)
	DpseGA11113	Uncharacterized protein. (173 aa)
	DpseGA16861	Uncharacterized protein. (2036 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NGT6	DpseGA17599	A0A0R3NGT6	A0A0R3P267	Uncharacterized protein, isoform E.	Uncharacterized protein, isoform D.	0.547
A0A0R3NH46	DpseGA14581	A0A0R3NH46	Q29NR4	Uncharacterized protein, isoform A.	Integrin beta; Belongs to the integrin beta chain family.	0.460
A0A0R3NH46	DpseGA17645	A0A0R3NH46	Q29M84	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.809
A0A0R3NH46	DpseGA23031	A0A0R3NH46	A0A0R3NYM7	Uncharacterized protein, isoform A.	Integrin beta; Belongs to the integrin beta chain family.	0.597
A0A0R3NJD9	A0A0R3NJU0	A0A0R3NJD9	A0A0R3NJU0	Uncharacterized protein, isoform G.	annotation not available	0.434
A0A0R3NJD9	DpseGA17590	A0A0R3NJD9	Q29HP2	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform B.	0.403
A0A0R3NJD9	DpseGA26093	A0A0R3NJD9	A0A0R3NTY0	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform J; Cadherins are calcium-dependent cell adhesion proteins.	0.453
A0A0R3NJD9	DpseGA27134	A0A0R3NJD9	A0A0R3NZM2	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform B.	0.403
A0A0R3NJD9	DpseGA30789	A0A0R3NJD9	A0A0R3P1H1	Uncharacterized protein, isoform G.	Uncharacterized protein.	0.517
A0A0R3NJD9	DpseGA32194	A0A0R3NJD9	A0A0R3P269	Uncharacterized protein, isoform G.	Uncharacterized protein.	0.517
A0A0R3NJD9	N6WCC8	A0A0R3NJD9	N6WCC8	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform D.	0.401
A0A0R3NJD9	Q28ZM3	A0A0R3NJD9	Q28ZM3	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform A.	0.401
A0A0R3NJD9	Q296A4	A0A0R3NJD9	Q296A4	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform A.	0.835
A0A0R3NJD9	arm	A0A0R3NJD9	Q29I35	Uncharacterized protein, isoform G.	Armadillo segment polarity protein; May associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis (By similarity). Belongs to the beta-catenin family.	0.711
A0A0R3NJU0	A0A0R3NJD9	A0A0R3NJU0	A0A0R3NJD9	annotation not available	Uncharacterized protein, isoform G.	0.434
A0A0R3NJU0	N6WCC8	A0A0R3NJU0	N6WCC8	annotation not available	Uncharacterized protein, isoform D.	0.699
A0A0R3NJU0	Q28ZM3	A0A0R3NJU0	Q28ZM3	annotation not available	Uncharacterized protein, isoform A.	0.699
A0A0R3NJU0	otk	A0A0R3NJU0	Q290N5	annotation not available	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).	0.589
A0A0R3NK49	otk	A0A0R3NK49	Q290N5	Uncharacterized protein, isoform A.	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).	0.649
A0A0R3NQG1	otk	A0A0R3NQG1	Q290N5	Uncharacterized protein, isoform A.	Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).	0.478