(60 nodes) Anatomical structure regression network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q28YB7	Uncharacterized protein. (1292 aa)
	Dpse_EcR	Ecdysone receptor. (700 aa)
	N6WCV6	Uncharacterized protein. (254 aa)
	I5APA0	annotation not available (889 aa)
	I5AMX5	Uncharacterized protein. (1133 aa)
	DpseGA20062	Uncharacterized protein. (218 aa)
	B5E1M6	Uncharacterized protein, isoform A. (899 aa)
	B5DYQ6	Uncharacterized protein. (244 aa)
	B5DW52	Transcription initiation factor TFIID TATA-box-binding protein. (642 aa)
	DpseGA23701	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (109 aa)
	DpseGA23962	Uncharacterized protein, isoform F. (1043 aa)
	DpseGA23468	Uncharacterized protein. (1924 aa)
	DpseGA24652	Uncharacterized protein, isoform A; Belongs to the BI1 family. (244 aa)
	DpseGA25980	Dynein light chain. (89 aa)
	DpseGA22662	Uncharacterized protein. (120 aa)
	DpseGA22910	Uncharacterized protein; Belongs to the BI1 family. (236 aa)
	DpseGA26073	Dynein light chain. (89 aa)
	DpseGA27749	Uncharacterized protein. (1143 aa)
	DpseGA16623	Uncharacterized protein, isoform G. (2553 aa)
	A0A0R3NKT1	Phosphoinositide-3-kinase, regulatory subunit 4. (1353 aa)
	A0A0R3NMH5	Uncharacterized protein, isoform A. (641 aa)
	A0A0R3NML8	Uncharacterized protein, isoform A. (448 aa)
	A0A0R3NP78	Uncharacterized protein, isoform A. (803 aa)
	A0A0R3NSK5	Transitional endoplasmic reticulum ATPase. (865 aa)
	A0A0R3NSV9	Uncharacterized protein, isoform A. (1515 aa)
	DpseGA19867	Uncharacterized protein, isoform E. (1051 aa)
	DpseGA19047	Uncharacterized protein, isoform C. (503 aa)
	DpseGA32390	Raptor_N domain-containing protein. (1683 aa)
	DpseGA18654	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family. (2501 aa)
	DpseGA20742	Uncharacterized protein, isoform B. (454 aa)
	DpseGA14058	Kinase; Belongs to the inositol phosphokinase (IPK) family. (682 aa)
	ap	Ap-PA. (469 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (269 aa)
	DpseGA19997	Rap-GAP domain-containing protein. (1864 aa)
	Eip74EF	Eip74EF. (748 aa)
	DpseGA21114	Uncharacterized protein, isoform A. (2561 aa)
	DpseGA20817	Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
	DpseGA18676	Uncharacterized protein. (405 aa)
	DpseGA18104	Uncharacterized protein. (72 aa)
	DpseGA10675	Protein kinase domain-containing protein. (859 aa)
	DpseGA14764	Uncharacterized protein, isoform A. (1059 aa)
	Trap100	Trap100. (992 aa)
	DpseGA11616	Uncharacterized protein. (1957 aa)
	rept	RuvB-like helicase 2; Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth (By similarity). (480 aa)
	Q29AP6	Isocitrate dehydrogenase (NAD+). (378 aa)
	Q298R4	Autophagy-related protein 13. (551 aa)
	Q298J9	Uncharacterized protein, isoform A. (1107 aa)
	Q298B5	Forkhead box protein A2, hepatocyte nuclear factor 3-beta. (613 aa)
	Q297T5	Uncharacterized protein. (348 aa)
	Q297M2	RB1-inducible coiled-coil protein 1. (1369 aa)
	Q297C1	Bromodomain and WD repeat domain containing protein 1/3. (2344 aa)
	Q296F8	Inositol 1,4,5-triphosphate receptor type 1. (2864 aa)
	Q295S9	DDB1- and CUL4-associated factor 12. (459 aa)
	Q293U0	Uncharacterized protein. (336 aa)
	Dpse_Atg9	Autophagy-related protein 9. (827 aa)
	Q290F5	Apoptotic protease-activating factor. (1489 aa)
	Q28ZN4	Ubiquitin-like modifier-activating enzyme ATG7. (681 aa)
	Q28ZE7	Phosphatidylinositol 3-kinase. (966 aa)
	Q28YQ8	Uncharacterized protein. (511 aa)
	Q28Y05	Ubiquitin-activating enzyme E1. (1184 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NKT1	A0A0R3NMH5	A0A0R3NKT1	A0A0R3NMH5	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein, isoform A.	0.847
A0A0R3NKT1	A0A0R3NML8	A0A0R3NKT1	A0A0R3NML8	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein, isoform A.	0.998
A0A0R3NKT1	Atg5	A0A0R3NKT1	Q3MQ15	Phosphoinositide-3-kinase, regulatory subunit 4.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.875
A0A0R3NKT1	DpseGA10675	A0A0R3NKT1	Q2LYW8	Phosphoinositide-3-kinase, regulatory subunit 4.	Protein kinase domain-containing protein.	0.993
A0A0R3NKT1	DpseGA11616	A0A0R3NKT1	Q29F75	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein.	0.678
A0A0R3NKT1	DpseGA18654	A0A0R3NKT1	A0A0R3P0E1	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	0.429
A0A0R3NKT1	DpseGA20062	A0A0R3NKT1	I5AMQ1	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein.	0.879
A0A0R3NKT1	DpseGA20742	A0A0R3NKT1	A0A0R3P2B7	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein, isoform B.	0.790
A0A0R3NKT1	DpseGA22662	A0A0R3NKT1	B5DLB9	Phosphoinositide-3-kinase, regulatory subunit 4.	Uncharacterized protein.	0.782
A0A0R3NKT1	DpseGA23701	A0A0R3NKT1	B5DQN4	Phosphoinositide-3-kinase, regulatory subunit 4.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.882
A0A0R3NKT1	DpseGA32390	A0A0R3NKT1	A0A0R3P030	Phosphoinositide-3-kinase, regulatory subunit 4.	Raptor_N domain-containing protein.	0.440
A0A0R3NKT1	Dpse_Atg9	A0A0R3NKT1	Q291S1	Phosphoinositide-3-kinase, regulatory subunit 4.	Autophagy-related protein 9.	0.869
A0A0R3NKT1	Q28ZE7	A0A0R3NKT1	Q28ZE7	Phosphoinositide-3-kinase, regulatory subunit 4.	Phosphatidylinositol 3-kinase.	0.999
A0A0R3NKT1	Q28ZN4	A0A0R3NKT1	Q28ZN4	Phosphoinositide-3-kinase, regulatory subunit 4.	Ubiquitin-like modifier-activating enzyme ATG7.	0.688
A0A0R3NKT1	Q297M2	A0A0R3NKT1	Q297M2	Phosphoinositide-3-kinase, regulatory subunit 4.	RB1-inducible coiled-coil protein 1.	0.863
A0A0R3NKT1	Q298R4	A0A0R3NKT1	Q298R4	Phosphoinositide-3-kinase, regulatory subunit 4.	Autophagy-related protein 13.	0.876
A0A0R3NMH5	A0A0R3NKT1	A0A0R3NMH5	A0A0R3NKT1	Uncharacterized protein, isoform A.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.847
A0A0R3NMH5	A0A0R3NML8	A0A0R3NMH5	A0A0R3NML8	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.901
A0A0R3NMH5	Atg5	A0A0R3NMH5	Q3MQ15	Uncharacterized protein, isoform A.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
A0A0R3NMH5	DpseGA10675	A0A0R3NMH5	Q2LYW8	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein.	0.928