(53 nodes) Branching involved in open tracheal system development network (Drosophila pseudoobscura)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0R3NF87	annotation not available (748 aa)
	A0A0R3NFX9	annotation not available (857 aa)
	A0A0R3NFY7	annotation not available (201 aa)
	A0A0R3NG95	Uncharacterized protein, isoform F. (729 aa)
	A0A0R3NJD9	Uncharacterized protein, isoform G. (2610 aa)
	A0A0R3NN44	Uncharacterized protein, isoform A. (8901 aa)
	A0A0R3NP93	annotation not available (982 aa)
	DpseGA32035	Protein kinase domain-containing protein. (157 aa)
	DpseGA32581	Uncharacterized protein. (182 aa)
	DpseGA18624	Uncharacterized protein, isoform C. (1562 aa)
	DpseGA19940	Uncharacterized protein, isoform B. (1664 aa)
	DpseGA18654	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family. (2501 aa)
	DpseGA19201	Uncharacterized protein, isoform B. (369 aa)
	DpseGA23590	Uncharacterized protein. (1640 aa)
	DpseGA23763	LRRCT domain-containing protein. (831 aa)
	DpseGA23845	Uncharacterized protein, isoform A. (718 aa)
	DpseGA28220	Guanylate cyclase. (1534 aa)
	B5E1G4	Uncharacterized protein, isoform A. (1517 aa)
	I5AMX5	Uncharacterized protein. (1133 aa)
	Q28WU6	Uncharacterized protein. (479 aa)
	Q28WU9	Uncharacterized protein, isoform H. (1649 aa)
	Q293L2	Uncharacterized protein, isoform A. (751 aa)
	Q293M1	V-type H+-transporting ATPase subunit G. (117 aa)
	Q295N3	V-type H+-transporting ATPase subunit E. (226 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	Q296B2	Hypoxia-inducible factor prolyl hydroxylase. (489 aa)
	Q296G6	Ras homolog enriched in brain. (182 aa)
	Q296J4	V-type H+-transporting ATPase 21kDa proteolipid subunit. (212 aa)
	Q297A1	Uncharacterized protein. (916 aa)
	Q297K0	T-complex protein 1 subunit gamma. (544 aa)
	Dpse_ttk	Tramtrack, isoform F. (829 aa)
	Q298B1	Uncharacterized protein. (746 aa)
	Q299T8	Activin receptor type-2B. (523 aa)
	Q29A52	V-type H+-transporting ATPase subunit d. (348 aa)
	Q29B14	Uncharacterized protein. (805 aa)
	DpseGA16614	Uncharacterized protein. (274 aa)
	DpseGA13429	Uncharacterized protein. (1422 aa)
	DpseGA12750	Uncharacterized protein. (573 aa)
	DpseGA15132	Uncharacterized protein, isoform A. (631 aa)
	DpseGA20725	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (443 aa)
	DpseGA19890	Uncharacterized protein, isoform B. (2865 aa)
	DpseGA15530	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
	DpseGA21510	Uncharacterized protein. (452 aa)
	Cdc42	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity). (191 aa)
	DpseGA13960	Uncharacterized protein, isoform A. (524 aa)
	DpseGA14821	Uncharacterized protein. (2048 aa)
	DpseGA15481	Uncharacterized protein, isoform A. (839 aa)
	DpseGA11750	Uncharacterized protein, isoform D. (1351 aa)
	DpseGA21362	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (897 aa)
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	Lam	Lam, isoform A; Belongs to the intermediate filament family. (617 aa)
	DpseGA18219	C2H2-type domain-containing protein. (537 aa)
	DpseGA10887	LRRCT domain-containing protein. (772 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R3NFX9	DpseGA15530	A0A0R3NFX9	Q29G85	annotation not available	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.955
A0A0R3NFX9	DpseGA18654	A0A0R3NFX9	A0A0R3P0E1	annotation not available	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	0.461
A0A0R3NFX9	Q293M1	A0A0R3NFX9	Q293M1	annotation not available	V-type H+-transporting ATPase subunit G.	0.936
A0A0R3NFX9	Q295N3	A0A0R3NFX9	Q295N3	annotation not available	V-type H+-transporting ATPase subunit E.	0.983
A0A0R3NFX9	Q296G6	A0A0R3NFX9	Q296G6	annotation not available	Ras homolog enriched in brain.	0.443
A0A0R3NFX9	Q296J4	A0A0R3NFX9	Q296J4	annotation not available	V-type H+-transporting ATPase 21kDa proteolipid subunit.	0.947
A0A0R3NFX9	Q29A52	A0A0R3NFX9	Q29A52	annotation not available	V-type H+-transporting ATPase subunit d.	0.945
A0A0R3NG95	Q28WU6	A0A0R3NG95	Q28WU6	Uncharacterized protein, isoform F.	Uncharacterized protein.	0.486
A0A0R3NG95	Q293L2	A0A0R3NG95	Q293L2	Uncharacterized protein, isoform F.	Uncharacterized protein, isoform A.	0.543
A0A0R3NG95	Ras85D	A0A0R3NG95	Q295X7	Uncharacterized protein, isoform F.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.430
A0A0R3NJD9	A0A0R3NP93	A0A0R3NJD9	A0A0R3NP93	Uncharacterized protein, isoform G.	annotation not available	0.646
A0A0R3NJD9	B5E1G4	A0A0R3NJD9	B5E1G4	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform A.	0.694
A0A0R3NJD9	Cdc42	A0A0R3NJD9	Q29HY3	Uncharacterized protein, isoform G.	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	0.686
A0A0R3NJD9	DpseGA19201	A0A0R3NJD9	A0A0R3P3L1	Uncharacterized protein, isoform G.	Uncharacterized protein, isoform B.	0.422
A0A0R3NJD9	DpseGA23590	A0A0R3NJD9	B5DPB2	Uncharacterized protein, isoform G.	Uncharacterized protein.	0.529
A0A0R3NN44	Cdc42	A0A0R3NN44	Q29HY3	Uncharacterized protein, isoform A.	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	0.422
A0A0R3NN44	DpseGA19201	A0A0R3NN44	A0A0R3P3L1	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.524
A0A0R3NP93	A0A0R3NJD9	A0A0R3NP93	A0A0R3NJD9	annotation not available	Uncharacterized protein, isoform G.	0.646
A0A0R3NP93	B5E1G4	A0A0R3NP93	B5E1G4	annotation not available	Uncharacterized protein, isoform A.	0.595
A0A0R3NP93	Cdc42	A0A0R3NP93	Q29HY3	annotation not available	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity).	0.808