10 items (Drosophila pseudoobscura) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	vir	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...] (1849 aa)
	fl(2)d	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...] (560 aa)
	Q28XF2	Uncharacterized protein. (704 aa)
	DpseGA10202	RING-type domain-containing protein. (433 aa)
	DpseGA17612	mRNA cap guanine-N7 methyltransferase. (408 aa)
	DpseGA20607	Uncharacterized protein; Belongs to the MT-A70-like family. (445 aa)
	DpseGA20292	Uncharacterized protein. (1249 aa)
	DpseGA19551	Uncharacterized protein. (786 aa)
	Q298L6	MRNA m6A methyltransferase catalytic subunit. (612 aa)
	Q290Y6	Uncharacterized protein. (803 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DpseGA10202	DpseGA20292	Q29PG8	Q29GD6	RING-type domain-containing protein.	Uncharacterized protein.	0.694
DpseGA10202	DpseGA20607	Q29PG8	Q29MN2	RING-type domain-containing protein.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.680
DpseGA10202	Q290Y6	Q29PG8	Q290Y6	RING-type domain-containing protein.	Uncharacterized protein.	0.597
DpseGA10202	Q298L6	Q29PG8	Q298L6	RING-type domain-containing protein.	MRNA m6A methyltransferase catalytic subunit.	0.677
DpseGA10202	fl(2)d	Q29PG8	Q28XY0	RING-type domain-containing protein.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.956
DpseGA10202	vir	Q29PG8	Q291E4	RING-type domain-containing protein.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.931
DpseGA17612	DpseGA19551	Q29P67	Q29G39	mRNA cap guanine-N7 methyltransferase.	Uncharacterized protein.	0.542
DpseGA17612	Q28XF2	Q29P67	Q28XF2	mRNA cap guanine-N7 methyltransferase.	Uncharacterized protein.	0.624
DpseGA19551	DpseGA17612	Q29G39	Q29P67	Uncharacterized protein.	mRNA cap guanine-N7 methyltransferase.	0.542
DpseGA20292	DpseGA10202	Q29GD6	Q29PG8	Uncharacterized protein.	RING-type domain-containing protein.	0.694
DpseGA20292	DpseGA20607	Q29GD6	Q29MN2	Uncharacterized protein.	Uncharacterized protein; Belongs to the MT-A70-like family.	0.803
DpseGA20292	Q290Y6	Q29GD6	Q290Y6	Uncharacterized protein.	Uncharacterized protein.	0.745
DpseGA20292	Q298L6	Q29GD6	Q298L6	Uncharacterized protein.	MRNA m6A methyltransferase catalytic subunit.	0.694
DpseGA20292	fl(2)d	Q29GD6	Q28XY0	Uncharacterized protein.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.996
DpseGA20292	vir	Q29GD6	Q291E4	Uncharacterized protein.	Protein virilizer; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx trans [...]	0.986
DpseGA20607	DpseGA10202	Q29MN2	Q29PG8	Uncharacterized protein; Belongs to the MT-A70-like family.	RING-type domain-containing protein.	0.680
DpseGA20607	DpseGA20292	Q29MN2	Q29GD6	Uncharacterized protein; Belongs to the MT-A70-like family.	Uncharacterized protein.	0.803
DpseGA20607	Q290Y6	Q29MN2	Q290Y6	Uncharacterized protein; Belongs to the MT-A70-like family.	Uncharacterized protein.	0.663
DpseGA20607	Q298L6	Q29MN2	Q298L6	Uncharacterized protein; Belongs to the MT-A70-like family.	MRNA m6A methyltransferase catalytic subunit.	0.996
DpseGA20607	fl(2)d	Q29MN2	Q28XY0	Uncharacterized protein; Belongs to the MT-A70-like family.	Pre-mRNA-splicing regulator female-lethal(2)D; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of [...]	0.976