(40 nodes) Negative regulation of cellular response to growth factor stimulus network (Drosophila pseudoobscura)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	sog	Short gastrulation. (231 aa)
	DpseGA23548	DEP domain-containing protein. (947 aa)
	Q291E3	Uncharacterized protein. (569 aa)
	Q290A2	Inner nuclear membrane protein Man1. (646 aa)
	Q28ZX5	Uncharacterized protein, isoform A. (1065 aa)
	Q28Z37	E3 ubiquitin ligase SMURF1/2. (1096 aa)
	Q28WU1	Uncharacterized protein, isoform A. (577 aa)
	B5E139	Uncharacterized protein, isoform A. (824 aa)
	brk	Brk. (747 aa)
	DpseGA16850	Uncharacterized protein. (807 aa)
	DpseGA19997	Rap-GAP domain-containing protein. (1864 aa)
	DpseGA19425	Uncharacterized protein, isoform C. (1065 aa)
	DpseGA21521	Uncharacterized protein, isoform A; Belongs to the DEAD box helicase family. (404 aa)
	DpseGA13508	Uncharacterized protein, isoform A; Belongs to the cullin family. (756 aa)
	DpseGA16549	Uncharacterized protein. (89 aa)
	DpseGA20095	Uncharacterized protein, isoform B. (1300 aa)
	DpseGA11537	Uncharacterized protein. (388 aa)
	DpseGA11471	Uncharacterized protein, isoform A. (921 aa)
	B5E0D1	Uncharacterized protein, isoform C. (713 aa)
	DpseGA28215	IGFBP N-terminal domain-containing protein. (290 aa)
	l(1)G0269	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...] (243 aa)
	DpseGA14821	Uncharacterized protein. (2048 aa)
	DpseGA17013	Uncharacterized protein, isoform B. (5568 aa)
	DpseGA13438	Uncharacterized protein. (248 aa)
	DpseGA12831	Uncharacterized protein, isoform A. (1034 aa)
	DpseGA19680	Protein kinase domain-containing protein. (811 aa)
	DpseGA19811	Uncharacterized protein. (1200 aa)
	DpseGA21595	Uncharacterized protein, isoform A. (570 aa)
	DpseGA15132	Uncharacterized protein, isoform A. (631 aa)
	Q298J9	Uncharacterized protein, isoform A. (1107 aa)
	Q297H8	Mothers against decapentaplegic homolog 6. (584 aa)
	Q296D8	Uncharacterized protein, isoform A. (578 aa)
	DpseGA32610	Uncharacterized protein. (840 aa)
	DpseGA19940	Uncharacterized protein, isoform B. (1664 aa)
	DpseGA11617	Uncharacterized protein, isoform B. (325 aa)
	DpseGA25453	Uncharacterized protein. (90 aa)
	DpseGA11663	Uncharacterized protein, isoform L. (4858 aa)
	DpseGA22411	c-SKI_SMAD_bind domain-containing protein. (801 aa)
	A0A0R3NQQ6	annotation not available (609 aa)
	DpseGA30824	Uncharacterized protein. (182 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5E139	sog	B5E139	A0A0R3NZB5	Uncharacterized protein, isoform A.	Short gastrulation.	0.657
DpseGA11537	Q296D8	Q29L74	Q296D8	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.650
DpseGA11617	sog	A0A0R3NZD5	A0A0R3NZB5	Uncharacterized protein, isoform B.	Short gastrulation.	0.482
DpseGA13438	sog	Q29GH6	A0A0R3NZB5	Uncharacterized protein.	Short gastrulation.	0.712
DpseGA15132	DpseGA19811	Q29DQ3	Q29F43	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.903
DpseGA19811	DpseGA15132	Q29F43	Q29DQ3	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.903
DpseGA19811	DpseGA19997	Q29F43	Q2M0Y0	Uncharacterized protein.	Rap-GAP domain-containing protein.	0.414
DpseGA19811	DpseGA32610	Q29F43	A0A0R3P289	Uncharacterized protein.	Uncharacterized protein.	0.766
DpseGA19997	DpseGA19811	Q2M0Y0	Q29F43	Rap-GAP domain-containing protein.	Uncharacterized protein.	0.414
DpseGA19997	DpseGA32610	Q2M0Y0	A0A0R3P289	Rap-GAP domain-containing protein.	Uncharacterized protein.	0.547
DpseGA19997	Q291E3	Q2M0Y0	Q291E3	Rap-GAP domain-containing protein.	Uncharacterized protein.	0.605
DpseGA19997	Q298J9	Q2M0Y0	Q298J9	Rap-GAP domain-containing protein.	Uncharacterized protein, isoform A.	0.999
DpseGA20095	Q28Z37	Q29MB7	Q28Z37	Uncharacterized protein, isoform B.	E3 ubiquitin ligase SMURF1/2.	0.490
DpseGA20095	Q297H8	Q29MB7	Q297H8	Uncharacterized protein, isoform B.	Mothers against decapentaplegic homolog 6.	0.617
DpseGA32610	DpseGA19811	A0A0R3P289	Q29F43	Uncharacterized protein.	Uncharacterized protein.	0.766
DpseGA32610	DpseGA19997	A0A0R3P289	Q2M0Y0	Uncharacterized protein.	Rap-GAP domain-containing protein.	0.547
DpseGA32610	Q298J9	A0A0R3P289	Q298J9	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.558
Q28Z37	DpseGA20095	Q28Z37	Q29MB7	E3 ubiquitin ligase SMURF1/2.	Uncharacterized protein, isoform B.	0.490
Q28Z37	Q297H8	Q28Z37	Q297H8	E3 ubiquitin ligase SMURF1/2.	Mothers against decapentaplegic homolog 6.	0.998
Q28ZX5	l(1)G0269	Q28ZX5	Q29I63	Uncharacterized protein, isoform A.	CTD nuclear envelope phosphatase 1 homolog; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). Belongs to t [...]	0.859