STRINGSTRING
A0A0R3NIX8 A0A0R3NIX8 A0A0R3NLW5 A0A0R3NLW5 A0A0R3NM77 A0A0R3NM77 A0A0R3NPH6 A0A0R3NPH6 A0A0R3NTF2 A0A0R3NTF2 DpseGA28948 DpseGA28948 A0A0R3NUS6 A0A0R3NUS6 A0A0R3NUT8 A0A0R3NUT8 DpseGA28114 DpseGA28114 DpseGA31311 DpseGA31311 DpseGA32030 DpseGA32030 DpseGA32116 DpseGA32116 DpseGA25201 DpseGA25201 DpseGA22965 DpseGA22965 DpseGA32509 DpseGA32509 DpseGA32073 DpseGA32073 DpseGA31790 DpseGA31790 DpseGA30562 DpseGA30562 DpseGA14011 DpseGA14011 DpseGA32770 DpseGA32770 DpseGA19054 DpseGA19054 DpseGA17613 DpseGA17613 DpseGA21506 DpseGA21506 A0A158SUI1 A0A158SUI1 DpseGA26008 DpseGA26008 DpseGA25698 DpseGA25698 NTH1 NTH1 DpseGA22760 DpseGA22760 DpseGA22977 DpseGA22977 DpseGA23082 DpseGA23082 DpseGA27396 DpseGA27396 DpseGA26098 DpseGA26098 DpseGA22843 DpseGA22843 DpseGA22336 DpseGA22336 DpseGA22360 DpseGA22360 DpseGA23822 DpseGA23822 DpseGA23629 DpseGA23629 DpseGA23614 DpseGA23614 DpseGA23686 DpseGA23686 DpseGA23655 DpseGA23655 DpseGA25552 DpseGA25552 DpseGA27639 DpseGA27639 Fen1 Fen1 DpseGA23279 DpseGA23279 DpseGA23277 DpseGA23277 DpseGA23278 DpseGA23278 B5DXG7 B5DXG7 slx1 slx1 B5DY22 B5DY22 B5DY62 B5DY62 B5DYF1 B5DYF1 B5DYF2 B5DYF2 B5DYG6 B5DYG6 B5DYR9 B5DYR9 B5DYS1 B5DYS1 B5E0G6 B5E0G6 B5E0W0 B5E0W0 B5E134 B5E134 B5E182 B5E182 B5E195 B5E195 B5E1F0 B5E1F0 B5E1L9 B5E1L9 DpseGA21257 DpseGA21257 DpseGA16470 DpseGA16470 DpseGA13651 DpseGA13651 I5ANY9 I5ANY9 I5APV4 I5APV4 I5APX2 I5APX2 I7LSU9 I7LSU9 DpseGA17582 DpseGA17582 I7M3J1 I7M3J1 Q28WM7 Q28WM7 Q28X10 Q28X10 Q28X67 Q28X67 Q28XA8 Q28XA8 Q28XG6 Q28XG6 Q28XK0 Q28XK0 Q28Y86 Q28Y86 Q28YB7 Q28YB7 Q28ZE6 Q28ZE6 Q28ZL9 Q28ZL9 Q28ZU1 Q28ZU1 Q290G0 Q290G0 Q291A3 Q291A3 Q291E2 Q291E2 Q292E9 Q292E9 Q292R0 Q292R0 Q292S4 Q292S4 Q292W9 Q292W9 Q293L0 Q293L0 Q293W3 Q293W3 Q294E5 Q294E5 Q295A4 Q295A4 Q295J3 Q295J3 Q295K1 Q295K1 Q296G1 Q296G1 Q297C3 Q297C3 Q298D7 Q298D7 Q299B2 Q299B2 Q299C5 Q299C5 WRNexo WRNexo Q299N5 Q299N5 Q299N6 Q299N6 Q29AH5 Q29AH5 Q29AI2 Q29AI2 Q29AN7 Q29AN7 Q29AR6 Q29AR6 Q29AU1 Q29AU1 Q29B03 Q29B03 Q29BB6 Q29BB6 Q29BD8 Q29BD8 Q29BD9 Q29BD9 Q29BF7 Q29BF7 Q29BI3 Q29BI3 Q29BJ1 Q29BJ1 DpseGA19370 DpseGA19370 DpseGA11591 DpseGA11591 DpseGA19253 DpseGA19253 DpseGA17708 DpseGA17708 DpseGA19896 DpseGA19896 DpseGA20389 DpseGA20389 DpseGA20130 DpseGA20130 DpseGA21025 DpseGA21025 DpseGA16881 DpseGA16881 DpseGA20886 DpseGA20886 DpseGA14227 DpseGA14227 DpseGA20026 DpseGA20026 DpseGA20548 DpseGA20548 Gen Gen DBR1 DBR1 DpseGA20165 DpseGA20165 DpseGA15732 DpseGA15732 DpseGA17620 DpseGA17620 DpseGA15547 DpseGA15547 DpseGA15562 DpseGA15562 DpseGA15089 DpseGA15089 DpseGA10780 DpseGA10780 DpseGA15266 DpseGA15266 DpseGA13271 DpseGA13271 DpseGA19537 DpseGA19537 DpseGA17094 DpseGA17094 DpseGA21908 DpseGA21908 DpseGA13257 DpseGA13257 DpseGA17195 DpseGA17195 DpseGA10268 DpseGA10268 DpseGA21456 DpseGA21456 DpseGA16366 DpseGA16366 DpseGA21770 DpseGA21770 DpseGA16873 DpseGA16873 DpseGA18324 DpseGA18324 DpseGA14597 DpseGA14597 DpseGA16580 DpseGA16580 DpseGA10293 DpseGA10293 DpseGA11550 DpseGA11550 DpseGA14221 DpseGA14221 DpseGA19417 DpseGA19417 DpseGA16923 DpseGA16923 DpseGA16496 DpseGA16496 DpseGA12461 DpseGA12461 DpseGA17805 DpseGA17805 DpseGA21643 DpseGA21643 DpseGA21642 DpseGA21642 DpseGA21638 DpseGA21638 DpseGA11094 DpseGA11094 DpseGA11511 DpseGA11511 DpseGA19382 DpseGA19382 DpseGA21555 DpseGA21555 DpseGA19506 DpseGA19506 DpseGA20274 DpseGA20274 DpseGA20769 DpseGA20769 DpseGA16659 DpseGA16659 DpseGA19891 DpseGA19891 DpseGA17795 DpseGA17795 DpseGA19405 DpseGA19405 DpseGA19028 DpseGA19028 DpseGA18767 DpseGA18767
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A0R3NIX8Eukaryotic translation initiation factor 2C. (679 aa)
A0A0R3NLW5Ankyrin repeat and LEM domain-containing protein 1. (257 aa)
A0A0R3NM77Uncharacterized protein, isoform A. (380 aa)
A0A0R3NPH6Uncharacterized protein, isoform F. (382 aa)
A0A0R3NTF2DNA-directed RNA polymerase III subunit RPC11. (108 aa)
DpseGA28948Uncharacterized protein, isoform B. (242 aa)
A0A0R3NUS6Uncharacterized protein, isoform A. (376 aa)
A0A0R3NUT8Pre-mRNA cleavage complex 2 protein Pcf11. (2003 aa)
DpseGA28114Uncharacterized protein, isoform B. (913 aa)
DpseGA31311Uncharacterized protein, isoform B. (911 aa)
DpseGA32030DDE Tnp4 domain-containing protein. (168 aa)
DpseGA32116Piwi domain-containing protein. (145 aa)
DpseGA25201Uncharacterized protein, isoform B. (1258 aa)
DpseGA22965ArgoN domain-containing protein. (219 aa)
DpseGA32509Uncharacterized protein, isoform A. (180 aa)
DpseGA32073Endo/exonuclease/phosphatase domain-containing protein. (375 aa)
DpseGA31790Alba domain-containing protein. (193 aa)
DpseGA30562PAZ domain-containing protein. (629 aa)
DpseGA14011Uncharacterized protein, isoform B. (546 aa)
DpseGA32770Piwi domain-containing protein. (121 aa)
DpseGA19054Uncharacterized protein, isoform B. (395 aa)
DpseGA17613Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (232 aa)
DpseGA21506Uncharacterized protein, isoform B. (763 aa)
A0A158SUI1Uncharacterized protein. (159 aa)
DpseGA26008Uncharacterized protein. (845 aa)
DpseGA25698Uncharacterized protein. (488 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (396 aa)
DpseGA22760Uncharacterized protein. (378 aa)
DpseGA22977Uncharacterized protein. (445 aa)
DpseGA23082Uncharacterized protein. (832 aa)
DpseGA27396RAI1 domain-containing protein. (379 aa)
DpseGA26098Uncharacterized protein, isoform A. (331 aa)
DpseGA22843Uncharacterized protein, isoform A. (331 aa)
DpseGA22336Uncharacterized protein. (308 aa)
DpseGA22360Uncharacterized protein. (331 aa)
DpseGA23822Uncharacterized protein. (274 aa)
DpseGA23629Uncharacterized protein. (946 aa)
DpseGA23614Uncharacterized protein, isoform A. (527 aa)
DpseGA23686Uncharacterized protein, isoform A. (385 aa)
DpseGA23655tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (279 aa)
DpseGA25552Uncharacterized protein. (481 aa)
DpseGA27639Uncharacterized protein. (568 aa)
Fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (386 aa)
DpseGA23279Exonuclease domain-containing protein. (223 aa)
DpseGA23277Uncharacterized protein, isoform A. (223 aa)
DpseGA23278Exonuclease domain-containing protein. (223 aa)
B5DXG7Pre-mRNA 3'-end-processing factor FIP1. (686 aa)
slx1Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (291 aa)
B5DY22Uncharacterized protein. (365 aa)
B5DY62Eukaryotic translation initiation factor 2C. (972 aa)
B5DYF1Uncharacterized protein. (338 aa)
B5DYF2Uncharacterized protein. (369 aa)
B5DYG6Cleavage and polyadenylation specificity factor subunit 2. (699 aa)
B5DYR9Eukaryotic translation initiation factor 2C. (980 aa)
B5DYS1Uncharacterized protein. (339 aa)
B5E0G6Meiotic recombination protein SPO11. (333 aa)
B5E0W0Uncharacterized protein. (135 aa)
B5E134Endonuclease G, mitochondrial. (304 aa)
B5E182Uncharacterized protein, isoform A. (217 aa)
B5E195Uncharacterized protein. (527 aa)
B5E1F0Exonuclease 3'-5' domain-containing protein 1. (1013 aa)
B5E1L9DNA excision repair protein ERCC-2. (769 aa)
DpseGA21257Uncharacterized protein. (713 aa)
DpseGA16470DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (675 aa)
DpseGA13651Uncharacterized protein. (486 aa)
I5ANY9CCR4-NOT transcription complex subunit 6. (551 aa)
I5APV4Uncharacterized protein, isoform C. (668 aa)
I5APX2Uncharacterized protein. (638 aa)
I7LSU9Uncharacterized protein. (359 aa)
DpseGA17582Uncharacterized protein. (282 aa)
I7M3J1Uncharacterized protein, isoform E. (324 aa)
Q28WM7Uncharacterized protein. (102 aa)
Q28X10Uncharacterized protein, isoform A. (1362 aa)
Q28X67Exosome complex component RRP42. (296 aa)
Q28XA8U3 small nucleolar RNA-associated protein 13. (787 aa)
Q28XG6Polynucleotide 5'-hydroxyl-kinase GRC3/NOL9. (896 aa)
Q28XK0Crossover junction endonuclease EME1. (309 aa)
Q28Y86PAB-dependent poly(A)-specific ribonuclease subunit 2. (1237 aa)
Q28YB7Uncharacterized protein. (1292 aa)
Q28ZE6Exosome complex component RRP4. (298 aa)
Q28ZL9DNA repair protein RAD50. (1309 aa)
Q28ZU1Eukaryotic translation initiation factor 2C. (985 aa)
Q290G0Uncharacterized protein. (763 aa)
Q291A3Uncharacterized protein, isoform A. (1726 aa)
Q291E2Cleavage and polyadenylation specificity factor subunit 1. (1459 aa)
Q292E9DNA excision repair protein ERCC-1. (260 aa)
Q292R0MRNA-decapping enzyme 1B. (343 aa)
Q292S4Uncharacterized protein. (661 aa)
Q292W9Uncharacterized protein, isoform A. (311 aa)
Q293L0Serine/threonine-protein kinase/endoribonuclease IRE1. (1083 aa)
Q293W3Uncharacterized protein. (370 aa)
Q294E5Uncharacterized protein. (535 aa)
Q295A4Exonuclease 3'-5' domain-containing protein 2. (578 aa)
Q295J3U6 snRNA phosphodiesterase. (255 aa)
Q295K1DNA polymerase alpha subunit A. (1474 aa)
Q296G1DNA cross-link repair 1A protein. (787 aa)
Q297C3Exosome complex exonuclease DIS3/RRP44. (978 aa)
Q298D7Uncharacterized protein. (950 aa)
Q299B2DNA-directed RNA polymerase II subunit RPB9. (134 aa)
Q299C5Uncharacterized protein. (217 aa)
WRNexoWerner Syndrome-like exonuclease; Essential for the formation of DNA replication focal centers. Has an important role in maintaining genome stability. Has exonuclease activity on both single-stranded and duplex templates bearing overhangs, but not blunt ended duplex DNA, and cleaves in a 3'-5' direction (By similarity); Belongs to the WRNexo family. (356 aa)
Q299N5Cleavage stimulation factor subunit 2. (418 aa)
Q299N6Cleavage and polyadenylation specificity factor subunit 3. (684 aa)
Q29AH5Ribosomal RNA-processing protein 36. (247 aa)
Q29AI2Exosome complex exonuclease RRP6. (905 aa)
Q29AN7Integrator complex subunit 11. (597 aa)
Q29AR6DNA-directed RNA polymerase I subunit RPA12. (121 aa)
Q29AU1Uncharacterized protein. (2280 aa)
Q29B03TatD DNase family protein. (321 aa)
Q29BB6Polyribonucleotide nucleotidyltransferase. (769 aa)
Q29BD8Uncharacterized protein, isoform A. (303 aa)
Q29BD9Uncharacterized protein. (299 aa)
Q29BF7Uncharacterized protein. (949 aa)
Q29BI3DNA polymerase epsilon subunit 1. (2242 aa)
Q29BJ1Uncharacterized protein. (346 aa)
DpseGA19370Uncharacterized protein; Belongs to the argonaute family. (848 aa)
DpseGA11591Lactamase_B domain-containing protein. (292 aa)
DpseGA19253DNA polymerase. (1093 aa)
DpseGA17708Uncharacterized protein. (423 aa)
DpseGA19896Endonuclease_NS domain-containing protein. (430 aa)
DpseGA2038960S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
DpseGA20130Smr domain-containing protein. (937 aa)
DpseGA21025Exonuclease domain-containing protein. (744 aa)
DpseGA16881Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (344 aa)
DpseGA20886Uncharacterized protein; Belongs to the RNase T2 family. (342 aa)
DpseGA14227RNB domain-containing protein; Belongs to the RNR ribonuclease family. (1151 aa)
DpseGA20026Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (928 aa)
DpseGA20548Bms1-type G domain-containing protein. (1164 aa)
GenFlap endonuclease GEN; Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5'- overhanging flap structures in which the 5'-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5' single-strand overhang of the flap is double-stranded. Also possesses weak 5'- to 3'- exonuclease activity on nicked but not gapped double-stranded DNA. Does not cleave bubble-like or Holliday junction substrates (By similarity). (754 aa)
DBR1Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. (537 aa)
DpseGA20165Uncharacterized protein, isoform A. (649 aa)
DpseGA15732ERCC4 domain-containing protein. (456 aa)
DpseGA17620Uncharacterized protein, isoform A. (973 aa)
DpseGA15547RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (466 aa)
DpseGA15562Uncharacterized protein. (1113 aa)
DpseGA15089Uncharacterized protein, isoform A. (375 aa)
DpseGA10780Uncharacterized protein. (383 aa)
DpseGA15266XendoU domain-containing protein. (616 aa)
DpseGA13271Uncharacterized protein. (98 aa)
DpseGA19537XPA_C domain-containing protein. (289 aa)
DpseGA17094AN1-type domain-containing protein. (418 aa)
DpseGA21908RNase_PH domain-containing protein. (398 aa)
DpseGA13257Exonuclease domain-containing protein. (822 aa)
DpseGA171955'-3' exoribonuclease 1. (1476 aa)
DpseGA102685'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (916 aa)
DpseGA21456POLAc domain-containing protein. (1169 aa)
DpseGA16366Exonuclease domain-containing protein. (335 aa)
DpseGA21770CIDE-N domain-containing protein. (456 aa)
DpseGA16873Uncharacterized protein. (271 aa)
DpseGA18324DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1363 aa)
DpseGA14597Uncharacterized protein. (244 aa)
DpseGA16580KH_dom_type_1 domain-containing protein. (232 aa)
DpseGA10293Uncharacterized protein. (709 aa)
DpseGA11550PLDc_2 domain-containing protein. (240 aa)
DpseGA14221Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (650 aa)
DpseGA19417Ge1_WD40 domain-containing protein. (1391 aa)
DpseGA16923Endonuclease. (317 aa)
DpseGA16496Uncharacterized protein. (244 aa)
DpseGA12461Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (358 aa)
DpseGA17805Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (394 aa)
DpseGA21643Uncharacterized protein. (491 aa)
DpseGA21642Uncharacterized protein, isoform A. (625 aa)
DpseGA21638Uncharacterized protein. (498 aa)
DpseGA11094Uncharacterized protein. (296 aa)
DpseGA11511DDE Tnp4 domain-containing protein. (389 aa)
DpseGA19382Uncharacterized protein, isoform A; Belongs to the argonaute family. (851 aa)
DpseGA21555Lactamase_B domain-containing protein. (224 aa)
DpseGA19506Uncharacterized protein, isoform A. (685 aa)
DpseGA20274Bms1-type G domain-containing protein. (815 aa)
DpseGA20769Uncharacterized protein. (797 aa)
DpseGA16659Uncharacterized protein. (490 aa)
DpseGA19891Exonuclease domain-containing protein. (278 aa)
DpseGA17795Cell cycle checkpoint control protein; Belongs to the rad9 family. (458 aa)
DpseGA19405Nudix hydrolase domain-containing protein. (817 aa)
DpseGA19028Kri1_C domain-containing protein. (871 aa)
DpseGA18767Ribosomal_L7Ae domain-containing protein. (160 aa)
Your Current Organism:
Drosophila pseudoobscura
NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura
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