(19 nodes) Regulation of reactive oxygen species metabolic process network (Drosophila pseudoobscura)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	DpseGA18654	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family. (2501 aa)
	DpseGA25337	AIRS_C domain-containing protein. (368 aa)
	DpseGA28926	Uncharacterized protein. (409 aa)
	DpseGA24104	AIRS_C domain-containing protein. (369 aa)
	DpseGA24615	Uncharacterized protein, isoform A. (365 aa)
	DpseGA28666	AIRS_C domain-containing protein. (358 aa)
	B5DXC1	Disintegrin and metalloproteinase domain-containing protein 17. (743 aa)
	B5DYR5	Insulin-like growth factor 1 receptor. (2293 aa)
	B5E1J5	Uncharacterized protein, isoform A. (424 aa)
	Q28X55	Uncharacterized protein, isoform A. (398 aa)
	Q28ZG4	Uncharacterized protein. (498 aa)
	Q296G6	Ras homolog enriched in brain. (182 aa)
	Q298J9	Uncharacterized protein, isoform A. (1107 aa)
	Q29A57	Nuclear factor erythroid 2, invertebrate. (1409 aa)
	Q29AY5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1112 aa)
	DpseGA20057	Arrestin_C domain-containing protein. (344 aa)
	DpseGA12984	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (215 aa)
	DpseGA20190	Uncharacterized protein. (407 aa)
	DpseGA10133	Uncharacterized protein, isoform B. (242 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5DYR5	DpseGA18654	B5DYR5	A0A0R3P0E1	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	0.510
B5DYR5	Q296G6	B5DYR5	Q296G6	Insulin-like growth factor 1 receptor.	Ras homolog enriched in brain.	0.483
B5DYR5	Q298J9	B5DYR5	Q298J9	Insulin-like growth factor 1 receptor.	Uncharacterized protein, isoform A.	0.550
B5DYR5	Q29A57	B5DYR5	Q29A57	Insulin-like growth factor 1 receptor.	Nuclear factor erythroid 2, invertebrate.	0.516
B5DYR5	Q29AY5	B5DYR5	Q29AY5	Insulin-like growth factor 1 receptor.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.958
B5E1J5	DpseGA10133	B5E1J5	A0A0R3NY52	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B.	0.891
DpseGA10133	B5E1J5	A0A0R3NY52	B5E1J5	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.891
DpseGA12984	Q29AY5	Q29IL9	Q29AY5	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.418
DpseGA18654	B5DYR5	A0A0R3P0E1	B5DYR5	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	Insulin-like growth factor 1 receptor.	0.510
DpseGA18654	Q28ZG4	A0A0R3P0E1	Q28ZG4	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.517
DpseGA18654	Q296G6	A0A0R3P0E1	Q296G6	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	Ras homolog enriched in brain.	0.998
DpseGA18654	Q298J9	A0A0R3P0E1	Q298J9	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein, isoform A.	0.952
DpseGA18654	Q29AY5	A0A0R3P0E1	Q29AY5	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.954
Q28ZG4	DpseGA18654	Q28ZG4	A0A0R3P0E1	Uncharacterized protein.	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	0.517
Q28ZG4	Q296G6	Q28ZG4	Q296G6	Uncharacterized protein.	Ras homolog enriched in brain.	0.560
Q296G6	B5DYR5	Q296G6	B5DYR5	Ras homolog enriched in brain.	Insulin-like growth factor 1 receptor.	0.483
Q296G6	DpseGA18654	Q296G6	A0A0R3P0E1	Ras homolog enriched in brain.	Uncharacterized protein, isoform B; Belongs to the PI3/PI4-kinase family.	0.998
Q296G6	Q28ZG4	Q296G6	Q28ZG4	Ras homolog enriched in brain.	Uncharacterized protein.	0.560
Q296G6	Q298J9	Q296G6	Q298J9	Ras homolog enriched in brain.	Uncharacterized protein, isoform A.	0.999
Q296G6	Q29AY5	Q296G6	Q29AY5	Ras homolog enriched in brain.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.599