(20 nodes) Nucleic acid-binding, OB-fold network (Drosophila pseudoobscura)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA13581	Uncharacterized protein. (113 aa)
	DpseGA21663	RPA_C domain-containing protein. (237 aa)
	DpseGA16580	KH_dom_type_1 domain-containing protein. (232 aa)
	Mcm6	DNA replication licensing factor Mcm6; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (815 aa)
	DpseGA20693	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (140 aa)
	DpseGA14216	AAA domain-containing protein; Belongs to the AAA ATPase family. (413 aa)
	DpseGA15566	Uncharacterized protein. (65 aa)
	DpseGA13327	AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa)
	GA16587	Probable RNA-binding protein EIF1AD; Belongs to the EIF1AD family. (163 aa)
	DpseGA21636	Uncharacterized protein, isoform A. (775 aa)
	DpseGA20275	Uncharacterized protein. (240 aa)
	DpseGA10862	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	DpseGA17461	AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa)
	DpseGA11728	Uncharacterized protein, isoform A. (256 aa)
	DpseGA21978	Uncharacterized protein, isoform A. (142 aa)
	DpseGA18569	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)
	DpseGA27654	Uncharacterized protein. (173 aa)
	RpS11	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (155 aa)
	DpseGA25627	Uncharacterized protein. (66 aa)
	DpseGA23502	Uncharacterized protein, isoform B. (341 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DpseGA10862	DpseGA20275	Q2M0A5	Q2LZ71	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	Uncharacterized protein.	0.998
DpseGA10862	DpseGA27654	Q2M0A5	Q294T7	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	Uncharacterized protein.	0.999
DpseGA11728	DpseGA13327	Q29FA8	Q29I61	Uncharacterized protein, isoform A.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.413
DpseGA11728	DpseGA15566	Q29FA8	Q29ID4	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.999
DpseGA11728	DpseGA20693	Q29FA8	Q29J58	Uncharacterized protein, isoform A.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.969
DpseGA11728	RpS11	Q29FA8	Q292D0	Uncharacterized protein, isoform A.	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.	0.999
DpseGA13327	DpseGA11728	Q29I61	Q29FA8	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein, isoform A.	0.413
DpseGA13327	DpseGA14216	Q29I61	Q29IU3	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.975
DpseGA13327	DpseGA17461	Q29I61	Q29HL5	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.963
DpseGA13581	DpseGA18569	Q29IE8	Q29D32	Uncharacterized protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.651
DpseGA13581	DpseGA21636	Q29IE8	Q29NT4	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.714
DpseGA13581	DpseGA21663	Q29IE8	Q29LY7	Uncharacterized protein.	RPA_C domain-containing protein.	0.999
DpseGA13581	Mcm6	Q29IE8	Q29JI9	Uncharacterized protein.	DNA replication licensing factor Mcm6; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.691
DpseGA14216	DpseGA13327	Q29IU3	Q29I61	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.975
DpseGA14216	DpseGA17461	Q29IU3	Q29HL5	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.963
DpseGA15566	DpseGA11728	Q29ID4	Q29FA8	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.999
DpseGA15566	DpseGA20693	Q29ID4	Q29J58	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.994
DpseGA15566	DpseGA25627	Q29ID4	B5DH72	Uncharacterized protein.	Uncharacterized protein.	0.900
DpseGA15566	GA16587	Q29ID4	Q29MZ0	Uncharacterized protein.	Probable RNA-binding protein EIF1AD; Belongs to the EIF1AD family.	0.586
DpseGA15566	RpS11	Q29ID4	Q292D0	Uncharacterized protein.	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.	0.999