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DpseGA20319 DpseGA20319 DpseGA22798 DpseGA22798 DpseGA20742 DpseGA20742 DpseGA19324 DpseGA19324 WDY WDY wuho wuho DpseGA23221 DpseGA23221 l(2)gl l(2)gl GA18610 GA18610 GA21511 GA21511 Lis-1 Lis-1 Ciao1 Ciao1 GA13204 GA13204 DpseGA19630 DpseGA19630 DpseGA21307 DpseGA21307 DpseGA10524 DpseGA10524 DpseGA12611 DpseGA12611 syd syd DpseGA10043 DpseGA10043 DpseGA15568 DpseGA15568 DpseGA20480 DpseGA20480 DpseGA17093 DpseGA17093 GA15597 GA15597 DpseGA10552 DpseGA10552 DpseGA14743 DpseGA14743 DpseGA14510 DpseGA14510 DpseGA10925 DpseGA10925 DpseGA21449 DpseGA21449 GA19813 GA19813 eIF3i eIF3i poe poe DpseGA13369 DpseGA13369 DpseGA18371 DpseGA18371 DpseGA20111 DpseGA20111 DpseGA17451 DpseGA17451 DpseGA18074 DpseGA18074 DpseGA14445 DpseGA14445 DpseGA18978 DpseGA18978 DpseGA20145 DpseGA20145 DpseGA10144 DpseGA10144 DpseGA10465 DpseGA10465 DpseGA18669 DpseGA18669 CG12134 CG12134 DpseGA23154 DpseGA23154 DpseGA32644 DpseGA32644
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DpseGA20319Uncharacterized protein, isoform E. (744 aa)
DpseGA22798Uncharacterized protein, isoform E. (664 aa)
DpseGA20742Uncharacterized protein, isoform B. (454 aa)
DpseGA19324Uncharacterized protein, isoform B. (585 aa)
WDYWD repeat-containing protein on Y chromosome. (1064 aa)
wuhotRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Required during gametogenesis; Belongs to the WD repeat TRM82 family. (396 aa)
DpseGA23221Uncharacterized protein. (634 aa)
l(2)glProtein lethal(2) giant larvae; Essential for the development of polarized epithelia, for cell polarity associated with asymmetric cell division of neuroblasts during development, and for oocyte polarity formation. Promotes the formation of actin-rich projections at the oocyte cortex and the posterior enrichment of par-1 which is required for oocyte polarization. Regulates the localization of axis-specifying morphogens such as stau and grk (By similarity). Could act as a tumor suppressor. (1166 aa)
GA18610Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (786 aa)
GA21511WD repeat-containing protein 48 homolog; Regulator of deubiquitinating complexes. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate (By similarity). (680 aa)
Lis-1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (411 aa)
Ciao1Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (335 aa)
GA13204WD repeat-containing protein 55 homolog; Belongs to the WD repeat WDR55 family. (503 aa)
DpseGA19630Uncharacterized protein, isoform A. (336 aa)
DpseGA21307WD_REPEATS_REGION domain-containing protein. (346 aa)
DpseGA10524WD_REPEATS_REGION domain-containing protein. (608 aa)
DpseGA12611Uncharacterized protein, isoform A. (1228 aa)
sydJNK-interacting protein 3; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK-signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. Syd is required for efficient kinesin-I mediated axonal transport (By similarity). (1235 aa)
DpseGA10043WD_REPEATS_REGION domain-containing protein. (740 aa)
DpseGA15568Uncharacterized protein, isoform A. (478 aa)
DpseGA20480Uncharacterized protein, isoform A. (634 aa)
DpseGA17093Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (769 aa)
GA15597Protein LST8 homolog. (315 aa)
DpseGA10552WD_REPEATS_REGION domain-containing protein. (356 aa)
DpseGA14743WD_REPEATS_REGION domain-containing protein. (473 aa)
DpseGA14510Uncharacterized protein, isoform A. (356 aa)
DpseGA10925Uncharacterized protein, isoform A. (488 aa)
DpseGA21449Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (377 aa)
GA19813Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (419 aa)
eIF3iEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (326 aa)
poeProtein purity of essence; Has a role in growth of the perineurial glial layer of the larval peripheral nerve. May have a role in male fertility and eye development or function. May bind calmodulin (By similarity). (5381 aa)
DpseGA13369WD_REPEATS_REGION domain-containing protein. (424 aa)
DpseGA18371Uncharacterized protein. (986 aa)
DpseGA20111Uncharacterized protein, isoform B. (318 aa)
DpseGA17451WD_REPEATS_REGION domain-containing protein. (347 aa)
DpseGA18074WD_REPEATS_REGION domain-containing protein. (532 aa)
DpseGA14445WD_REPEATS_REGION domain-containing protein. (317 aa)
DpseGA18978Uncharacterized protein. (401 aa)
DpseGA20145WD_REPEATS_REGION domain-containing protein. (1169 aa)
DpseGA10144Uncharacterized protein, isoform A. (413 aa)
DpseGA10465Uncharacterized protein, isoform A. (383 aa)
DpseGA18669WD_REPEATS_REGION domain-containing protein. (427 aa)
CG12134CG12134-PA. (411 aa)
DpseGA23154Uncharacterized protein, isoform C. (340 aa)
DpseGA32644Uncharacterized protein. (325 aa)
Your Current Organism:
Drosophila pseudoobscura
NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura
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