48 items (Drosophila pseudoobscura) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA10862	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	DpseGA20571	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (531 aa)
	DpseGA19492	Uncharacterized protein; Belongs to the cyclin family. (1137 aa)
	DpseGA10767	General transcription factor IIH subunit. (445 aa)
	DpseGA20328	Uncharacterized protein; Belongs to the cyclin family. (324 aa)
	DpseGA20769	Uncharacterized protein. (797 aa)
	DpseGA20468	Uncharacterized protein, isoform A. (1175 aa)
	DpseGA17632	Uncharacterized protein. (313 aa)
	DpseGA19897	RNA_pol_L_2 domain-containing protein. (117 aa)
	DpseGA18615	Uncharacterized protein. (298 aa)
	DpseGA20659	RPOLD domain-containing protein. (275 aa)
	DpseGA13578	Uncharacterized protein; Belongs to the cyclin family. (423 aa)
	DpseGA17354	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
	RpII215	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1889 aa)
	DpseGA22166	Uncharacterized protein. (578 aa)
	DpseGA17103	Uncharacterized protein. (590 aa)
	Q29BZ5	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	Q29B30	Uncharacterized protein, isoform A. (2182 aa)
	Q29B09	Negative elongation factor A. (1271 aa)
	Q29A62	Uncharacterized protein. (699 aa)
	Q299M1	Uncharacterized protein. (260 aa)
	Q299B2	DNA-directed RNA polymerase II subunit RPB9. (134 aa)
	Q298X6	DNA-directed RNA polymerase II subunit RPB2. (1176 aa)
	Q296B8	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (131 aa)
	DpseGA27687	Uncharacterized protein, isoform B; Belongs to the SKP1 family. (139 aa)
	DpseGA19284	Uncharacterized protein, isoform B. (287 aa)
	DpseGA28879	Uncharacterized protein. (73 aa)
	DpseGA22626	Uncharacterized protein. (401 aa)
	DpseGA22602	Uncharacterized protein. (210 aa)
	DpseGA22581	Uncharacterized protein. (214 aa)
	DpseGA23520	Uncharacterized protein, isoform A. (1126 aa)
	DpseGA23928	Uncharacterized protein, isoform A. (1115 aa)
	B5DXG4	Transcription initiation factor TFIIF subunit alpha. (576 aa)
	B5DXW9	Transcription initiation factor TFIIF subunit alpha. (558 aa)
	B5DY77	Uncharacterized protein. (118 aa)
	B5E0K0	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
	B5E1D3	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (57 aa)
	B5E1L9	DNA excision repair protein ERCC-2. (769 aa)
	Q28X88	RNA polymerase II subunit A C-terminal domain phosphatase. (873 aa)
	Q28XJ6	CDK-activating kinase assembly factor MAT1. (320 aa)
	Q290H4	Cyclin-dependent kinase 9. (402 aa)
	Q291K0	Transcription initiation factor TFIIH subunit 1. (587 aa)
	Q292N9	Transcription elongation factor SPT4. (116 aa)
	Q292S1	Transcription elongation factor SPT5. (1080 aa)
	Ssrp	FACT complex subunit Ssrp1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (727 aa)
	Q293R4	Transcription initiation factor TFIIF subunit beta. (282 aa)
	Q294C6	Uncharacterized protein. (386 aa)
	DpseGA27654	Uncharacterized protein. (173 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5DXG4	B5DXW9	B5DXG4	B5DXW9	Transcription initiation factor TFIIF subunit alpha.	Transcription initiation factor TFIIF subunit alpha.	0.904
B5DXG4	B5DY77	B5DXG4	B5DY77	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein.	0.497
B5DXG4	B5E0K0	B5DXG4	B5E0K0	Transcription initiation factor TFIIF subunit alpha.	DNA-directed RNA polymerases I, II, and III subunit RPABC1.	0.827
B5DXG4	B5E1D3	B5DXG4	B5E1D3	Transcription initiation factor TFIIF subunit alpha.	DNA-directed RNA polymerases I, II, and III subunit RPABC4.	0.924
B5DXG4	B5E1L9	B5DXG4	B5E1L9	Transcription initiation factor TFIIF subunit alpha.	DNA excision repair protein ERCC-2.	0.927
B5DXG4	DpseGA10767	B5DXG4	Q2M0P7	Transcription initiation factor TFIIF subunit alpha.	General transcription factor IIH subunit.	0.933
B5DXG4	DpseGA10862	B5DXG4	Q2M0A5	Transcription initiation factor TFIIF subunit alpha.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.916
B5DXG4	DpseGA13578	B5DXG4	Q29JQ2	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein; Belongs to the cyclin family.	0.583
B5DXG4	DpseGA17103	B5DXG4	Q29G99	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein.	0.505
B5DXG4	DpseGA17354	B5DXG4	Q29J32	Transcription initiation factor TFIIF subunit alpha.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.660
B5DXG4	DpseGA17632	B5DXG4	Q29P72	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein.	0.798
B5DXG4	DpseGA18615	B5DXG4	Q29LH3	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein.	0.841
B5DXG4	DpseGA19284	B5DXG4	A0A0R3P7I6	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein, isoform B.	0.616
B5DXG4	DpseGA19492	B5DXG4	Q2M0U3	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein; Belongs to the cyclin family.	0.563
B5DXG4	DpseGA19897	B5DXG4	Q29MR4	Transcription initiation factor TFIIF subunit alpha.	RNA_pol_L_2 domain-containing protein.	0.930
B5DXG4	DpseGA20328	B5DXG4	Q2M0B7	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein; Belongs to the cyclin family.	0.833
B5DXG4	DpseGA20571	B5DXG4	Q2M1D2	Transcription initiation factor TFIIF subunit alpha.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.945
B5DXG4	DpseGA20659	B5DXG4	Q29K78	Transcription initiation factor TFIIF subunit alpha.	RPOLD domain-containing protein.	0.936
B5DXG4	DpseGA20769	B5DXG4	Q2LZJ4	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein.	0.938
B5DXG4	DpseGA22581	B5DXG4	B5DLP1	Transcription initiation factor TFIIF subunit alpha.	Uncharacterized protein.	0.827