66 items (Drosophila pseudoobscura) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DpseGA17103	Uncharacterized protein. (590 aa)
	B5E0E7	Uncharacterized protein. (352 aa)
	B5E0K0	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
	DpseGA17632	Uncharacterized protein. (313 aa)
	DpseGA19897	RNA_pol_L_2 domain-containing protein. (117 aa)
	DpseGA18615	Uncharacterized protein. (298 aa)
	lilli	AF4/FMR2 family member lilli; Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation (By similarity); Bel [...] (1770 aa)
	DpseGA20659	RPOLD domain-containing protein. (275 aa)
	DpseGA13578	Uncharacterized protein; Belongs to the cyclin family. (423 aa)
	DpseGA17354	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
	RpII215	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1889 aa)
	DpseGA11664	Plus3 domain-containing protein. (247 aa)
	B5E1D3	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (57 aa)
	Eaf	Ell-associated factor Eaf; Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development (By similarity); Belongs to the EAF family. (564 aa)
	B5E1L9	DNA excision repair protein ERCC-2. (769 aa)
	Q28X88	RNA polymerase II subunit A C-terminal domain phosphatase. (873 aa)
	B5DY77	Uncharacterized protein. (118 aa)
	Q28XJ6	CDK-activating kinase assembly factor MAT1. (320 aa)
	Q28XQ3	Uncharacterized protein. (499 aa)
	Q28XT6	RNA polymerase-associated protein RTF1. (764 aa)
	Q290H4	Cyclin-dependent kinase 9. (402 aa)
	Q291K0	Transcription initiation factor TFIIH subunit 1. (587 aa)
	Q292N9	Transcription elongation factor SPT4. (116 aa)
	Q292S1	Transcription elongation factor SPT5. (1080 aa)
	Ssrp	FACT complex subunit Ssrp1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (727 aa)
	Q293R4	Transcription initiation factor TFIIF subunit beta. (282 aa)
	Cbp20	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs [...] (154 aa)
	Q294A7	YEATS domain-containing protein 1/3. (969 aa)
	Q294C6	Uncharacterized protein. (386 aa)
	Q294I1	Uncharacterized protein. (540 aa)
	DpseGA27654	Uncharacterized protein. (173 aa)
	Q295Y2	RNA polymerase II-associated factor 1. (559 aa)
	Q296B8	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (131 aa)
	Q298X6	DNA-directed RNA polymerase II subunit RPB2. (1176 aa)
	Q299B2	DNA-directed RNA polymerase II subunit RPB9. (134 aa)
	Q299M1	Uncharacterized protein. (260 aa)
	Q29A62	Uncharacterized protein. (699 aa)
	DpseGA22166	Uncharacterized protein. (578 aa)
	DpseGA11490	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1857 aa)
	DpseGA22119	TFIIS N-terminal domain-containing protein. (656 aa)
	Q29B09	Negative elongation factor A. (1271 aa)
	Q29B68	WD repeat-containing protein 61. (332 aa)
	Q29BZ5	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	DpseGA15373	TPR_REGION domain-containing protein. (1193 aa)
	Cbp80	Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp80 does not bind directly capped RNAs [...] (800 aa)
	A0A0R3NF67	Solute carrier family 39 (zinc transporter), member 13. (404 aa)
	DpseGA27687	Uncharacterized protein, isoform B; Belongs to the SKP1 family. (139 aa)
	DpseGA19284	Uncharacterized protein, isoform B. (287 aa)
	DpseGA25764	Uncharacterized protein. (219 aa)
	DpseGA28879	Uncharacterized protein. (73 aa)
	DpseGA22626	Uncharacterized protein. (401 aa)
	DpseGA22602	Uncharacterized protein. (210 aa)
	DpseGA22581	Uncharacterized protein. (214 aa)
	DpseGA23520	Uncharacterized protein, isoform A. (1126 aa)
	DpseGA23928	Uncharacterized protein, isoform A. (1115 aa)
	DpseGA23238	Uncharacterized protein, isoform B. (616 aa)
	B5DWF5	RNA polymerase-associated protein LEO1. (719 aa)
	B5DXG4	Transcription initiation factor TFIIF subunit alpha. (576 aa)
	B5DXW9	Transcription initiation factor TFIIF subunit alpha. (558 aa)
	DpseGA20571	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (531 aa)
	DpseGA19492	Uncharacterized protein; Belongs to the cyclin family. (1137 aa)
	DpseGA10767	General transcription factor IIH subunit. (445 aa)
	DpseGA20328	Uncharacterized protein; Belongs to the cyclin family. (324 aa)
	DpseGA10862	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	DpseGA20769	Uncharacterized protein. (797 aa)
	DpseGA16406	Uncharacterized protein, isoform A. (646 aa)

Your Current Organism:

Drosophila pseudoobscura

NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B5DWF5	B5DY77	B5DWF5	B5DY77	RNA polymerase-associated protein LEO1.	Uncharacterized protein.	0.677
B5DWF5	B5E0E7	B5DWF5	B5E0E7	RNA polymerase-associated protein LEO1.	Uncharacterized protein.	0.970
B5DWF5	B5E0K0	B5DWF5	B5E0K0	RNA polymerase-associated protein LEO1.	DNA-directed RNA polymerases I, II, and III subunit RPABC1.	0.719
B5DWF5	B5E1D3	B5DWF5	B5E1D3	RNA polymerase-associated protein LEO1.	DNA-directed RNA polymerases I, II, and III subunit RPABC4.	0.878
B5DWF5	Cbp20	B5DWF5	Q293V6	RNA polymerase-associated protein LEO1.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs [...]	0.433
B5DWF5	DpseGA10862	B5DWF5	Q2M0A5	RNA polymerase-associated protein LEO1.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.876
B5DWF5	DpseGA11490	B5DWF5	Q29GF4	RNA polymerase-associated protein LEO1.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.949
B5DWF5	DpseGA11664	B5DWF5	Q29HQ2	RNA polymerase-associated protein LEO1.	Plus3 domain-containing protein.	0.873
B5DWF5	DpseGA13578	B5DWF5	Q29JQ2	RNA polymerase-associated protein LEO1.	Uncharacterized protein; Belongs to the cyclin family.	0.577
B5DWF5	DpseGA15373	B5DWF5	Q29EV9	RNA polymerase-associated protein LEO1.	TPR_REGION domain-containing protein.	0.988
B5DWF5	DpseGA16406	B5DWF5	Q29PE7	RNA polymerase-associated protein LEO1.	Uncharacterized protein, isoform A.	0.873
B5DWF5	DpseGA17632	B5DWF5	Q29P72	RNA polymerase-associated protein LEO1.	Uncharacterized protein.	0.841
B5DWF5	DpseGA19897	B5DWF5	Q29MR4	RNA polymerase-associated protein LEO1.	RNA_pol_L_2 domain-containing protein.	0.872
B5DWF5	DpseGA20659	B5DWF5	Q29K78	RNA polymerase-associated protein LEO1.	RPOLD domain-containing protein.	0.911
B5DWF5	DpseGA22119	B5DWF5	Q29GE4	RNA polymerase-associated protein LEO1.	TFIIS N-terminal domain-containing protein.	0.889
B5DWF5	DpseGA22581	B5DWF5	B5DLP1	RNA polymerase-associated protein LEO1.	Uncharacterized protein.	0.719
B5DWF5	DpseGA22602	B5DWF5	B5DLL1	RNA polymerase-associated protein LEO1.	Uncharacterized protein.	0.719
B5DWF5	DpseGA23238	B5DWF5	B5DUZ9	RNA polymerase-associated protein LEO1.	Uncharacterized protein, isoform B.	0.873
B5DWF5	DpseGA23520	B5DWF5	B5DPP2	RNA polymerase-associated protein LEO1.	Uncharacterized protein, isoform A.	0.991
B5DWF5	DpseGA25764	B5DWF5	B5DIC5	RNA polymerase-associated protein LEO1.	Uncharacterized protein.	0.968