STRINGSTRING
A0A0R3NJV7 A0A0R3NJV7 A0A0R3NL39 A0A0R3NL39 A0A0R3NP93 A0A0R3NP93 A0A0R3NPB9 A0A0R3NPB9 A0A0R3NPG6 A0A0R3NPG6 A0A0R3NRL4 A0A0R3NRL4 DpseGA25056 DpseGA25056 DpseGA10508 DpseGA10508 DpseGA32035 DpseGA32035 DpseGA30839 DpseGA30839 DpseGA22747 DpseGA22747 DpseGA20319 DpseGA20319 DpseGA18611 DpseGA18611 DpseGA23568 DpseGA23568 DpseGA19342 DpseGA19342 DpseGA32527 DpseGA32527 DpseGA28374 DpseGA28374 DpseGA23356 DpseGA23356 DpseGA28399 DpseGA28399 DpseGA11989 DpseGA11989 DpseGA28338 DpseGA28338 DpseGA31256 DpseGA31256 DpseGA25309 DpseGA25309 DpseGA25842 DpseGA25842 DpseGA25830 DpseGA25830 DpseGA25763 DpseGA25763 DpseGA25864 DpseGA25864 DpseGA28986 DpseGA28986 DpseGA29067 DpseGA29067 DpseGA22926 DpseGA22926 DpseGA22609 DpseGA22609 DpseGA22602 DpseGA22602 DpseGA22581 DpseGA22581 DpseGA25684 DpseGA25684 DpseGA22328 DpseGA22328 DpseGA22354 DpseGA22354 DpseGA23814 DpseGA23814 DpseGA23402 DpseGA23402 DpseGA28491 DpseGA28491 DpseGA28339 DpseGA28339 DpseGA28589 DpseGA28589 DpseGA22496 DpseGA22496 B5DVH3 B5DVH3 B5DVX8 B5DVX8 B5DW47 B5DW47 B5DW52 B5DW52 B5DXG4 B5DXG4 B5DXW9 B5DXW9 B5DXY4 B5DXY4 B5DYB4 B5DYB4 B5DYM1 B5DYM1 B5DYM7 B5DYM7 B5DYR5 B5DYR5 B5E0K0 B5E0K0 B5E1D3 B5E1D3 B5E1M6 B5E1M6 I5ANI6 I5ANI6 I5APP3 I5APP3 I5APP4 I5APP4 N6VFI0 N6VFI0 N6WCS2 N6WCS2 Hsp83 Hsp83 Q28WR3 Q28WR3 Dpse_EcR Dpse_EcR Q28XM9 Q28XM9 Q28Y04 Q28Y04 Q28YC1 Q28YC1 Q28YK4 Q28YK4 Q28ZA3 Q28ZA3 Q28ZV9 Q28ZV9 Q290H4 Q290H4 Q290Q4 Q290Q4 Q292B8 Q292B8 Q292Y3 Q292Y3 Q293R4 Q293R4 Q294A1 Q294A1 Q294C6 Q294C6 DpseGA27654 DpseGA27654 Q294U1 Q294U1 Q294V1 Q294V1 Q295S3 Q295S3 Ras85D Ras85D Q296B8 Q296B8 Q297G9 Q297G9 Q297X4 Q297X4 Q298B5 Q298B5 foxo foxo Q298X6 Q298X6 Q299B2 Q299B2 Q299B6 Q299B6 Q29A01 Q29A01 Q29AC1 Q29AC1 Q29AW2 Q29AW2 Q29AW5 Q29AW5 Art4 Art4 Q29BD4 Q29BD4 Q29BZ5 Q29BZ5 DpseGA15309 DpseGA15309 DpseGA20999 DpseGA20999 DpseGA21741 DpseGA21741 DpseGA20722 DpseGA20722 DpseGA10606 DpseGA10606 DpseGA10039 DpseGA10039 DpseGA17637 DpseGA17637 DpseGA10483 DpseGA10483 DpseGA20327 DpseGA20327 DpseGA13644 DpseGA13644 run run DpseGA13742 DpseGA13742 DpseGA15484 DpseGA15484 DpseGA23114 DpseGA23114 DpseGA14519 DpseGA14519 DpseGA14568 DpseGA14568 DpseGA19369 DpseGA19369 DpseGA14764 DpseGA14764 DpseGA20040 DpseGA20040 DpseGA20028 DpseGA20028 DpseGA17725 DpseGA17725 RpII215 RpII215 DpseGA15325 DpseGA15325 DpseGA12823 DpseGA12823 DpseGA18146 DpseGA18146 DpseGA10556 DpseGA10556 DpseGA12050 DpseGA12050 DpseGA20659 DpseGA20659 DpseGA19805 DpseGA19805 DpseGA13701 DpseGA13701 DpseGA20441 DpseGA20441 DpseGA13859 DpseGA13859 DpseGA19897 DpseGA19897 DpseGA17928 DpseGA17928 DpseGA18239 DpseGA18239 DpseGA13373 DpseGA13373 DpseGA17605 DpseGA17605 DpseGA21656 DpseGA21656 DpseGA18768 DpseGA18768 DpseGA12246 DpseGA12246 DpseGA17661 DpseGA17661 DpseGA20345 DpseGA20345 DpseGA19341 DpseGA19341 DpseGA20146 DpseGA20146 DpseGA10862 DpseGA10862 DpseGA17962 DpseGA17962 DpseGA19492 DpseGA19492
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A0R3NJV7Cytosolic prostaglandin-E synthase. (184 aa)
A0A0R3NL39annotation not available (508 aa)
A0A0R3NP93annotation not available (982 aa)
A0A0R3NPB9KN motif and ankyrin repeat domain-containing protein. (1349 aa)
A0A0R3NPG6Uncharacterized protein, isoform B. (331 aa)
A0A0R3NRL4Uncharacterized protein, isoform A. (422 aa)
DpseGA25056Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (392 aa)
DpseGA10508Uncharacterized protein, isoform B. (973 aa)
DpseGA32035Protein kinase domain-containing protein. (157 aa)
DpseGA30839Uncharacterized protein. (560 aa)
DpseGA22747SANT domain-containing protein. (3296 aa)
DpseGA20319Uncharacterized protein, isoform E. (744 aa)
DpseGA18611Uncharacterized protein, isoform E. (828 aa)
DpseGA23568Uncharacterized protein, isoform C. (348 aa)
DpseGA19342Uncharacterized protein, isoform E. (360 aa)
DpseGA32527Uncharacterized protein. (370 aa)
DpseGA28374Uncharacterized protein. (1043 aa)
DpseGA23356Uncharacterized protein, isoform B. (1058 aa)
DpseGA28399Uncharacterized protein, isoform D. (915 aa)
DpseGA11989Uncharacterized protein, isoform B. (1102 aa)
DpseGA28338Tyrosine-protein kinase. (552 aa)
DpseGA31256Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
DpseGA25309Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (557 aa)
DpseGA25842Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (340 aa)
DpseGA25830Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (687 aa)
DpseGA25763Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (414 aa)
DpseGA25864Aldedh domain-containing protein. (133 aa)
DpseGA28986Uncharacterized protein. (322 aa)
DpseGA29067Aldedh domain-containing protein. (133 aa)
DpseGA22926Uncharacterized protein, isoform A. (313 aa)
DpseGA22609Uncharacterized protein, isoform A. (868 aa)
DpseGA22602Uncharacterized protein. (210 aa)
DpseGA22581Uncharacterized protein. (214 aa)
DpseGA25684Runt domain-containing protein. (648 aa)
DpseGA22328Uncharacterized protein, isoform A. (318 aa)
DpseGA22354Uncharacterized protein. (726 aa)
DpseGA23814Uncharacterized protein. (213 aa)
DpseGA23402Uncharacterized protein. (1516 aa)
DpseGA28491Uncharacterized protein; Belongs to the DEAD box helicase family. (545 aa)
DpseGA28339Protein kinase domain-containing protein. (234 aa)
DpseGA28589Uncharacterized protein; Belongs to the DEAD box helicase family. (799 aa)
DpseGA22496Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
B5DVH3Type I protein arginine methyltransferase. (351 aa)
B5DVX8Fatty acid-binding protein 3, muscle and heart. (145 aa)
B5DW47Ras-related protein Ral-A. (200 aa)
B5DW52Transcription initiation factor TFIID TATA-box-binding protein. (642 aa)
B5DXG4Transcription initiation factor TFIIF subunit alpha. (576 aa)
B5DXW9Transcription initiation factor TFIIF subunit alpha. (558 aa)
B5DXY4Uncharacterized protein. (436 aa)
B5DYB4Serine/threonine-protein phosphatase 5. (522 aa)
B5DYM1Transcription initiation factor TFIIA small subunit. (129 aa)
B5DYM7Type I protein arginine methyltransferase. (450 aa)
B5DYR5Insulin-like growth factor 1 receptor. (2293 aa)
B5E0K0DNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
B5E1D3DNA-directed RNA polymerases I, II, and III subunit RPABC4. (57 aa)
B5E1M6Uncharacterized protein, isoform A. (899 aa)
I5ANI6Transcription initiation factor TFIIA large subunit. (359 aa)
I5APP3Uncharacterized protein, isoform C. (496 aa)
I5APP4Uncharacterized protein, isoform C. (963 aa)
N6VFI0Pyruvate dehydrogenase kinase 2/3/4. (423 aa)
N6WCS2Carnitine O-palmitoyltransferase 1, liver isoform. (782 aa)
Hsp83Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for piRNA biogenesis by facilitating loading of piRNAs into PIW [...] (717 aa)
Q28WR3Palmitoyltransferase ZDHHC3/7/25. (286 aa)
Dpse_EcREcdysone receptor. (700 aa)
Q28XM9Uncharacterized protein, isoform A. (1439 aa)
Q28Y04Uncharacterized protein. (244 aa)
Q28YC1Uncharacterized protein. (148 aa)
Q28YK4Uncharacterized protein, isoform A. (332 aa)
Q28ZA3Uncharacterized protein, isoform D. (355 aa)
Q28ZV9Uncharacterized protein. (388 aa)
Q290H4Cyclin-dependent kinase 9. (402 aa)
Q290Q4Retinol dehydrogenase 13. (327 aa)
Q292B8Transcription initiation factor TFIID TATA-box-binding protein. (345 aa)
Q292Y3Uncharacterized protein. (311 aa)
Q293R4Transcription initiation factor TFIIF subunit beta. (282 aa)
Q294A1S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase. (379 aa)
Q294C6Uncharacterized protein. (386 aa)
DpseGA27654Uncharacterized protein. (173 aa)
Q294U1Uncharacterized protein. (725 aa)
Q294V1RAC serine/threonine-protein kinase. (530 aa)
Q295S3Uncharacterized protein. (314 aa)
Ras85DRas-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
Q296B8DNA-directed RNA polymerases I, II, and III subunit RPABC2. (131 aa)
Q297G9Type I protein arginine methyltransferase. (376 aa)
Q297X4ATP-dependent RNA helicase DDX5/DBP2. (738 aa)
Q298B5Forkhead box protein A2, hepatocyte nuclear factor 3-beta. (613 aa)
foxoForkhead box protein O; Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself m [...] (644 aa)
Q298X6DNA-directed RNA polymerase II subunit RPB2. (1176 aa)
Q299B2DNA-directed RNA polymerase II subunit RPB9. (134 aa)
Q299B6Transcription initiation factor TFIIA small subunit. (105 aa)
Q29A01Alcohol dehydrogenase (NADP+). (329 aa)
Q29AC1Pyruvate dehydrogenase E1 component beta subunit. (365 aa)
Q29AW2All-trans-retinol dehydrogenase (NAD+). (319 aa)
Q29AW5Uncharacterized protein, isoform A. (363 aa)
Art4Histone-arginine methyltransferase CARMER; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins. May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling (By similarity). (531 aa)
Q29BD4Uncharacterized protein. (894 aa)
Q29BZ5DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
DpseGA15309Uncharacterized protein, isoform A. (312 aa)
DpseGA20999Uncharacterized protein. (384 aa)
DpseGA21741Uncharacterized protein. (236 aa)
DpseGA20722Uncharacterized protein. (213 aa)
DpseGA10606Aldo_ket_red domain-containing protein. (317 aa)
DpseGA10039Uncharacterized protein. (355 aa)
DpseGA17637Uncharacterized protein. (423 aa)
DpseGA10483Uncharacterized protein. (319 aa)
DpseGA20327Uncharacterized protein, isoform A. (597 aa)
DpseGA13644Uncharacterized protein. (3273 aa)
runRun, isoform A. (558 aa)
DpseGA13742Runt domain-containing protein. (694 aa)
DpseGA15484Uncharacterized protein. (201 aa)
DpseGA23114Uncharacterized protein. (218 aa)
DpseGA14519DAGKc domain-containing protein. (673 aa)
DpseGA14568BHLH domain-containing protein. (492 aa)
DpseGA19369Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (557 aa)
DpseGA14764Uncharacterized protein, isoform A. (1059 aa)
DpseGA20040Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (437 aa)
DpseGA20028Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (399 aa)
DpseGA17725Uncharacterized protein, isoform A; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (394 aa)
RpII215DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1889 aa)
DpseGA15325Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (323 aa)
DpseGA12823Uncharacterized protein, isoform A; Belongs to the small heat shock protein (HSP20) family. (193 aa)
DpseGA18146Uncharacterized protein. (487 aa)
DpseGA10556Uncharacterized protein, isoform A. (939 aa)
DpseGA12050Uncharacterized protein, isoform B. (2127 aa)
DpseGA20659RPOLD domain-containing protein. (275 aa)
DpseGA19805Nitric oxide synthase; Produces nitric oxide (NO). (1348 aa)
DpseGA13701Uncharacterized protein. (240 aa)
DpseGA20441Uncharacterized protein. (220 aa)
DpseGA13859Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
DpseGA19897RNA_pol_L_2 domain-containing protein. (117 aa)
DpseGA17928Uncharacterized protein. (694 aa)
DpseGA18239Peptidylprolyl isomerase. (440 aa)
DpseGA13373Uncharacterized protein, isoform B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa)
DpseGA17605Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (366 aa)
DpseGA21656Uncharacterized protein, isoform A; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (425 aa)
DpseGA18768Uncharacterized protein, isoform A. (515 aa)
DpseGA12246Uncharacterized protein, isoform A. (1062 aa)
DpseGA17661Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (521 aa)
DpseGA20345Dihydrolipoyl dehydrogenase. (504 aa)
DpseGA19341Aldo_ket_red domain-containing protein. (326 aa)
DpseGA20146Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1146 aa)
DpseGA10862DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
DpseGA17962Uncharacterized protein. (810 aa)
DpseGA19492Uncharacterized protein; Belongs to the cyclin family. (1137 aa)
Your Current Organism:
Drosophila pseudoobscura
NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura
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