STRINGSTRING
SMF23324.1 SMF23324.1 SME95836.1 SME95836.1 SME95844.1 SME95844.1 SME95850.1 SME95850.1 SME95856.1 SME95856.1 hemC hemC SME97159.1 SME97159.1 SMF32557.1 SMF32557.1 cobD cobD cobQ cobQ SMF32591.1 SMF32591.1 SMF32624.1 SMF32624.1 SMF32633.1 SMF32633.1 SMF32643.1 SMF32643.1 SMF32656.1 SMF32656.1 SMF32660.1 SMF32660.1 SMF32670.1 SMF32670.1 SMF32681.1 SMF32681.1 SMF32702.1 SMF32702.1 SMF32713.1 SMF32713.1 SMF32720.1 SMF32720.1 SMF32730.1 SMF32730.1 cbiD cbiD SMF32749.1 SMF32749.1 cobB cobB SMF34264.1 SMF34264.1 hemE hemE SMF40489.1 SMF40489.1 SMF40499.1 SMF40499.1 SMF40507.1 SMF40507.1 SMF45610.1 SMF45610.1 SMF48025.1 SMF48025.1 SMF50809.1 SMF50809.1 SMF52710.1 SMF52710.1 SMF67603.1 SMF67603.1 cobS cobS cobT cobT SMF68312.1 SMF68312.1 SMF69538.1 SMF69538.1 SMF69542.1 SMF69542.1 SMF70160.1 SMF70160.1 SMF72205.1 SMF72205.1 hemF hemF hemH hemH SMF09887.1 SMF09887.1 SMF16865.1 SMF16865.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMF23324.1Hypothetical protein. (460 aa)
SME95836.1Membrane protein. (324 aa)
SME95844.1Short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
SME95850.1Hypoxia induced protein conserved region. (67 aa)
SME95856.1cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (334 aa)
SME97159.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (236 aa)
SMF32557.1L-threonine O-3-phosphate decarboxylase. (342 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (485 aa)
SMF32591.1cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (204 aa)
SMF32624.1Predicted metal-binding protein. (132 aa)
SMF32633.1Cobalamin biosynthesis protein CobW. (345 aa)
SMF32643.1Cobaltochelatase CobN. (1106 aa)
SMF32656.1precorrin-3B synthase. (443 aa)
SMF32660.1precorrin-8X methylmutase. (209 aa)
SMF32670.1Precorrin-2/cobalt-factor-2 C20-methyltransferase. (254 aa)
SMF32681.1precorrin-3B C17-methyltransferase. (258 aa)
SMF32702.1precorrin-6A/cobalt-precorrin-6A reductase. (255 aa)
SMF32713.1precorrin-6Y C5,15-methyltransferase (decarboxylating). (417 aa)
SMF32720.1Cobalt-precorrin 5A hydrolase. (133 aa)
SMF32730.1Precorrin-4/cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (260 aa)
cbiDcobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (381 aa)
SMF32749.1uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (259 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (437 aa)
SMF34264.1Putative membrane protein. (181 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (344 aa)
SMF40489.1Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (397 aa)
SMF40499.1XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (214 aa)
SMF40507.1Catechol 2,3-dioxygenase. (134 aa)
SMF45610.1Cyclopropane-fatty-acyl-phospholipid synthase. (418 aa)
SMF48025.1Hypothetical protein. (434 aa)
SMF50809.1Porphobilinogen synthase; Belongs to the ALAD family. (340 aa)
SMF52710.1Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
SMF67603.1uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (480 aa)
cobSCobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (236 aa)
cobTNicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (343 aa)
SMF68312.1cob(II)yrinic acid a,c-diamide reductase. (228 aa)
SMF69538.1NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family. (204 aa)
SMF69542.1Nitroreductase. (198 aa)
SMF70160.1Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (173 aa)
SMF72205.1Uncharacterized conserved protein GlcG, DUF336 family. (140 aa)
hemFCoproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (303 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (344 aa)
SMF09887.1uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (541 aa)
SMF16865.1FMN reductase. (203 aa)
Your Current Organism:
Rhizobium oryzae
NCBI taxonomy Id: 464029
Other names: Allorhizobium oryzae, Allorhizobium oryzae (Peng et al. 2008) Mousavi et al. 2016, CGMCC 1.7048, HAMBI 3197, LMG 24253, LMG:24253, R. oryzae, Rhizobium oryzae Peng et al. 2008, strain Alt 505
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