STRINGSTRING
SME98312.1 SME98312.1 SMF21617.1 SMF21617.1 SMF11210.1 SMF11210.1 pqqE pqqE SMF10861.1 SMF10861.1 SMF09887.1 SMF09887.1 gltX gltX hemH hemH SMF04676.1 SMF04676.1 SMF03903.1 SMF03903.1 SMF03891.1 SMF03891.1 hmuV hmuV map-2 map-2 SMF46204.1 SMF46204.1 SMF41813.1 SMF41813.1 SMF74319.1 SMF74319.1 hemF hemF SMF73537.1 SMF73537.1 SMF72897.1 SMF72897.1 SMF72230.1 SMF72230.1 SMF72205.1 SMF72205.1 SMF70160.1 SMF70160.1 SMF68705.1 SMF68705.1 SMF68697.1 SMF68697.1 SMF67874.1 SMF67874.1 cobT cobT cobS cobS SMF67603.1 SMF67603.1 map map tig tig SMF52710.1 SMF52710.1 ctaA ctaA SMF50809.1 SMF50809.1 SMF46780.1 SMF46780.1 ctaB ctaB SMF40489.1 SMF40489.1 SMF40233.1 SMF40233.1 SMF40001.1 SMF40001.1 SMF37060.1 SMF37060.1 hemE hemE SMF34264.1 SMF34264.1 SMF33414.1 SMF33414.1 cobB cobB SMF32749.1 SMF32749.1 cbiD cbiD SMF32730.1 SMF32730.1 SMF32720.1 SMF32720.1 SMF32713.1 SMF32713.1 SMF32702.1 SMF32702.1 SMF32681.1 SMF32681.1 SMF32670.1 SMF32670.1 SMF32660.1 SMF32660.1 SMF32656.1 SMF32656.1 SMF32643.1 SMF32643.1 SMF32591.1 SMF32591.1 cobQ cobQ cobD cobD SMF32557.1 SMF32557.1 SMF59211.1 SMF59211.1 SMF57933.1 SMF57933.1 SME97159.1 SME97159.1 hemC hemC SME96598.1 SME96598.1 SME96282.1 SME96282.1 SME96255.1 SME96255.1 SME95856.1 SME95856.1 SME95800.1 SME95800.1 SMF55835.1 SMF55835.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SME98312.1MoxR-like ATPase. (279 aa)
SMF21617.1Oxygen-independent coproporphyrinogen-3 oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (450 aa)
SMF11210.1Pyrroloquinoline quinone biosynthesis protein D. (99 aa)
pqqEPyrroloquinoline quinone biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (365 aa)
SMF10861.1SnoaL-like domain-containing protein. (148 aa)
SMF09887.1uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (541 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (485 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (344 aa)
SMF04676.1General stress protein 26. (170 aa)
SMF03903.1Hypothetical protein. (174 aa)
SMF03891.1Heme-degrading monooxygenase HmoA. (114 aa)
hmuVIron complex transport system ATP-binding protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (260 aa)
map-2Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (251 aa)
SMF46204.1Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (195 aa)
SMF41813.1Broad specificity phosphatase PhoE. (208 aa)
SMF74319.1MoxR-like ATPase. (337 aa)
hemFCoproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (303 aa)
SMF73537.1Antibiotic biosynthesis monooxygenase. (116 aa)
SMF72897.1tRNA (mo5U34)-methyltransferase. (251 aa)
SMF72230.1Hypothetical protein. (106 aa)
SMF72205.1Uncharacterized conserved protein GlcG, DUF336 family. (140 aa)
SMF70160.1Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (173 aa)
SMF68705.1MoxR-like ATPase. (310 aa)
SMF68697.1cob(II)yrinic acid a,c-diamide reductase. (181 aa)
SMF67874.1Uncharacterized membrane protein. (136 aa)
cobTNicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (343 aa)
cobSCobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (236 aa)
SMF67603.1uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (480 aa)
mapMethionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (278 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (497 aa)
SMF52710.1Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
ctaACytochrome c oxidase assembly protein subunit 15; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. (366 aa)
SMF50809.1Porphobilinogen synthase; Belongs to the ALAD family. (340 aa)
SMF46780.1Heme-degrading monooxygenase HmoA. (115 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (318 aa)
SMF40489.1Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (397 aa)
SMF40233.1Starvation-inducible DNA-binding protein; Belongs to the Dps family. (172 aa)
SMF40001.1NADH dehydrogenase. (326 aa)
SMF37060.116S rRNA (guanine1207-N2)-methyltransferase; Belongs to the methyltransferase superfamily. (335 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (344 aa)
SMF34264.1Putative membrane protein. (181 aa)
SMF33414.1Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (161 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (437 aa)
SMF32749.1uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (259 aa)
cbiDcobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (381 aa)
SMF32730.1Precorrin-4/cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (260 aa)
SMF32720.1Cobalt-precorrin 5A hydrolase. (133 aa)
SMF32713.1precorrin-6Y C5,15-methyltransferase (decarboxylating). (417 aa)
SMF32702.1precorrin-6A/cobalt-precorrin-6A reductase. (255 aa)
SMF32681.1precorrin-3B C17-methyltransferase. (258 aa)
SMF32670.1Precorrin-2/cobalt-factor-2 C20-methyltransferase. (254 aa)
SMF32660.1precorrin-8X methylmutase. (209 aa)
SMF32656.1precorrin-3B synthase. (443 aa)
SMF32643.1Cobaltochelatase CobN. (1106 aa)
SMF32591.1cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (204 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (485 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa)
SMF32557.1L-threonine O-3-phosphate decarboxylase. (342 aa)
SMF59211.1Threonine kinase. (296 aa)
SMF57933.1Mn-containing catalase (includes spore coat protein CotJC). (308 aa)
SME97159.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (236 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (334 aa)
SME96598.15-aminolevulinate synthase. (404 aa)
SME96282.1Cobaltochelatase CobS subunit. (330 aa)
SME96255.1Cobaltochelatase CobT subunit. (632 aa)
SME95856.1cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
SME95800.1glutamyl-Q tRNA(Asp) synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (293 aa)
SMF55835.1Uncharacterized conserved protein GlcG, DUF336 family. (144 aa)
Your Current Organism:
Rhizobium oryzae
NCBI taxonomy Id: 464029
Other names: Allorhizobium oryzae, Allorhizobium oryzae (Peng et al. 2008) Mousavi et al. 2016, CGMCC 1.7048, HAMBI 3197, LMG 24253, LMG:24253, R. oryzae, Rhizobium oryzae Peng et al. 2008, strain Alt 505
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