(23 nodes) Glycerophospholipid metabolism, and Aquaporin-like network (Streptomyces sp. Mg1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKL64669.1	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase. (334 aa)
	AKL64670.1	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family. (281 aa)
	AKL64672.1	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (570 aa)
	AKL65043.1	Dihydroxyacetone kinase. (198 aa)
	AKL65044.1	PTS fructose transporter subunit IIA. (136 aa)
	AKL65192.1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (196 aa)
	AKL69859.1	Acyl-phosphate glycerol 3-phosphate acyltransferase. (209 aa)
	AKL65450.1	Glycerol transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. (260 aa)
	glpK-2	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (514 aa)
	AKL65451.1	Glycerol-3-phosphate dehydrogenase. (535 aa)
	AKL65531.1	Acyl-phosphate glycerol 3-phosphate acyltransferase. (215 aa)
	AKL66866.1	Glycerophosphodiester phosphodiesterase. (266 aa)
	AKL70104.1	Major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (328 aa)
	AKL67474.1	Glycerol-3-phosphate dehydrogenase. (568 aa)
	AKL67665.1	Glycerophosphodiester phosphodiesterase. (255 aa)
	AKL67961.1	Cytidyltransferase. (156 aa)
	AKL68059.1	Acyltransferase. (250 aa)
	gpsA	Glycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (336 aa)
	AKL68133.1	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (357 aa)
	AKL68205.1	Glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (218 aa)
	AKL68745.1	Acyl-phosphate glycerol 3-phosphate acyltransferase. (236 aa)
	AKL68797.1	Transcriptional regulator. (428 aa)
	AKL69574.1	CDP-diacylglycerol phosphatidylhydrolase. (234 aa)

Your Current Organism:

Streptomyces sp. Mg1

NCBI taxonomy Id: 465541
Other names: S. sp. Mg1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKL64669.1	AKL64670.1	M444_03760	M444_03765	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.687
AKL64669.1	AKL64672.1	M444_03760	M444_03775	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	0.872
AKL64669.1	AKL65043.1	M444_03760	M444_06165	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Dihydroxyacetone kinase.	0.998
AKL64669.1	AKL65044.1	M444_03760	M444_06170	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	PTS fructose transporter subunit IIA.	0.999
AKL64669.1	AKL65450.1	M444_03760	M444_08635	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Glycerol transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.490
AKL64669.1	AKL65451.1	M444_03760	M444_08645	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Glycerol-3-phosphate dehydrogenase.	0.824
AKL64669.1	AKL67474.1	M444_03760	M444_21050	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Glycerol-3-phosphate dehydrogenase.	0.824
AKL64669.1	AKL68797.1	M444_03760	M444_28990	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Transcriptional regulator.	0.889
AKL64669.1	gpsA	M444_03760	M444_24545	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	Glycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	0.823
AKL64670.1	AKL64669.1	M444_03765	M444_03760	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	0.687
AKL64670.1	AKL64672.1	M444_03765	M444_03775	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	0.872
AKL64670.1	AKL65043.1	M444_03765	M444_06165	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Dihydroxyacetone kinase.	0.437
AKL64670.1	AKL65044.1	M444_03765	M444_06170	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	PTS fructose transporter subunit IIA.	0.504
AKL64670.1	AKL65451.1	M444_03765	M444_08645	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerol-3-phosphate dehydrogenase.	0.726
AKL64670.1	AKL66866.1	M444_03765	M444_17370	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerophosphodiester phosphodiesterase.	0.421
AKL64670.1	AKL67474.1	M444_03765	M444_21050	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerol-3-phosphate dehydrogenase.	0.745
AKL64670.1	AKL67665.1	M444_03765	M444_22145	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerophosphodiester phosphodiesterase.	0.421
AKL64670.1	glpK-2	M444_03765	M444_08640	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.843
AKL64670.1	gpsA	M444_03765	M444_24545	Porin; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.	0.413
AKL64672.1	AKL64669.1	M444_03775	M444_03760	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase.	0.872