STRINGSTRING
AKL66613.1 AKL66613.1 AKL66652.1 AKL66652.1 AKL66690.1 AKL66690.1 pat pat AKL66903.1 AKL66903.1 AKL66917.1 AKL66917.1 AKL67026.1 AKL67026.1 AKL67100.1 AKL67100.1 kynU kynU AKL67129.1 AKL67129.1 hemL hemL AKL67367.1 AKL67367.1 AKL67394.1 AKL67394.1 AKL67450.1 AKL67450.1 AKL67495.1 AKL67495.1 rocD rocD glyA glyA AKL67533.1 AKL67533.1 AKL67590.1 AKL67590.1 AKL67594.1 AKL67594.1 AKL67608.1 AKL67608.1 AKL67682.1 AKL67682.1 AKL67719.1 AKL67719.1 kgd kgd lysA lysA AKL67882.1 AKL67882.1 glyA-2 glyA-2 AKL67931.1 AKL67931.1 AKL67949.1 AKL67949.1 glyA-3 glyA-3 AKL67991.1 AKL67991.1 AKL68015.1 AKL68015.1 AKL68135.1 AKL68135.1 AKL70284.1 AKL70284.1 AKL68158.1 AKL68158.1 AKL70297.1 AKL70297.1 AKL68241.1 AKL68241.1 AKL68330.1 AKL68330.1 AKL68331.1 AKL68331.1 dxs dxs AKL68446.1 AKL68446.1 AKL68492.1 AKL68492.1 AKL68513.1 AKL68513.1 AKL70336.1 AKL70336.1 AKL68584.1 AKL68584.1 AKL68667.1 AKL68667.1 bioA bioA AKL68734.1 AKL68734.1 AKL68768.1 AKL68768.1 AKL68799.1 AKL68799.1 AKL68953.1 AKL68953.1 AKL70406.1 AKL70406.1 AKL68954.1 AKL68954.1 lysA-2 lysA-2 AKL68993.1 AKL68993.1 AKL69083.1 AKL69083.1 AKL69151.1 AKL69151.1 AKL69380.1 AKL69380.1 AKL69584.1 AKL69584.1 AKL69410.1 AKL69410.1 AKL64173.1 AKL64173.1 AKL64221.1 AKL64221.1 AKL64295.1 AKL64295.1 AKL69697.1 AKL69697.1 AKL64545.1 AKL64545.1 AKL64788.1 AKL64788.1 lnyHI lnyHI lnyHH lnyHH lnyHF lnyHF lnyHE lnyHE lnyHD lnyHD lnyHC lnyHC lnyHB lnyHB kbl kbl AKL65070.1 AKL65070.1 AKL65124.1 AKL65124.1 AKL65133.1 AKL65133.1 gcvP gcvP AKL65217.1 AKL65217.1 AKL65278.1 AKL65278.1 argD argD AKL65448.1 AKL65448.1 AKL69904.1 AKL69904.1 AKL65641.1 AKL65641.1 hisC hisC AKL65780.1 AKL65780.1 AKL65851.1 AKL65851.1 AKL66147.1 AKL66147.1 AKL66201.1 AKL66201.1 AKL66217.1 AKL66217.1 AKL66231.1 AKL66231.1 AKL66339.1 AKL66339.1 AKL66405.1 AKL66405.1 AKL66480.1 AKL66480.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKL66613.1Aspartate/tyrosine/aromatic aminotransferase. (388 aa)
AKL66652.1Phosphoserine aminotransferase. (373 aa)
AKL66690.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine. (424 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (360 aa)
AKL66903.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine. (387 aa)
AKL66917.1Alanine racemase. (343 aa)
AKL67026.1Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
AKL67100.1Aminotransferase. (392 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (401 aa)
AKL67129.1Hypothetical protein. (450 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (398 aa)
AKL67367.12-oxoacid:ferredoxin oxidoreductase subunit beta. (352 aa)
AKL67394.1Aspartate aminotransferase. (408 aa)
AKL67450.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (379 aa)
AKL67495.1methylmalonyl-CoA mutase. (133 aa)
rocDOrnithine--oxo-acid aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
AKL67533.1methylmalonyl-CoA mutase. (526 aa)
AKL67590.1Cystathionine gamma-synthase. (385 aa)
AKL67594.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine. (410 aa)
AKL67608.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor. (403 aa)
AKL67682.1Pyridoxal-5'-phosphate-dependent protein subunit beta. (370 aa)
AKL67719.1N-succinyldiaminopimelate aminotransferase; Catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis. (364 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth. (1298 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
AKL67882.1L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (356 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa)
AKL67931.1methylmalonyl-CoA mutase. (566 aa)
AKL67949.1Glycogen phosphorylase. (881 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
AKL67991.1Cysteine desulfurase. (387 aa)
AKL68015.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate. (626 aa)
AKL68135.1ABC transporter substrate-binding protein. (366 aa)
AKL70284.1Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
AKL68158.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
AKL70297.12,4-diaminobutyrate 4-aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
AKL68241.1Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (961 aa)
AKL68330.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate. (733 aa)
AKL68331.1methylmalonyl-CoA mutase. (636 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
AKL68446.1Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Belongs to the TPP enzyme family. (580 aa)
AKL68492.1Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Belongs to the TPP enzyme family. (592 aa)
AKL68513.1GntR family transcriptional regulator. (495 aa)
AKL70336.1Aminotransferase class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
AKL68584.1Aminopeptidase. (408 aa)
AKL68667.1Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (469 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (440 aa)
AKL68734.18-amino-7-oxononanoate synthase. (398 aa)
AKL68768.1Aspartate aminotransferase. (396 aa)
AKL68799.1Molybdenum cofactor biosysynthesis protein. (181 aa)
AKL68953.1Hypothetical protein. (1976 aa)
AKL70406.1Polyketide synthase subunit. (3736 aa)
AKL68954.1Polyketide synthase subunit. (1618 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (444 aa)
AKL68993.1Aminotransferase class I and II. (434 aa)
AKL69083.1Glutamate decarboxylase. (463 aa)
AKL69151.1Oxidoreductase. (329 aa)
AKL69380.1Aminotransferase. (388 aa)
AKL69584.1Cobalamin-binding protein. (361 aa)
AKL69410.1Thiamine pyrophosphate-binding protein; Belongs to the TPP enzyme family. (577 aa)
AKL64173.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor. (404 aa)
AKL64221.1Aminotransferase. (377 aa)
AKL64295.1Hypothetical protein. (69 aa)
AKL69697.1Hypothetical protein. (2808 aa)
AKL64545.1Histidine decarboxylase. (547 aa)
AKL64788.1Amino acid adenylation protein. (1306 aa)
lnyHIPolyketide synthase. (5601 aa)
lnyHHPolyketide synthase. (7489 aa)
lnyHFPolyketide synthase. (5396 aa)
lnyHEPolyketide synthase. (5218 aa)
lnyHDPolyketide synthase. (1632 aa)
lnyHCPolyketide synthase. (6677 aa)
lnyHBPolyketide synthase. (3435 aa)
kbl2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (402 aa)
AKL65070.1Molybdenum cofactor biosysynthesis protein. (274 aa)
AKL65124.1Threonine dehydratase. (311 aa)
AKL65133.1Erythronolide synthase. (2382 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
AKL65217.1GntR family transcriptional regulator. (500 aa)
AKL65278.1Thiamine pyrophosphate-binding protein; Belongs to the TPP enzyme family. (547 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (407 aa)
AKL65448.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1170 aa)
AKL69904.1Aminotransferase. (352 aa)
AKL65641.1Cysteine desulfurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
hisCAspartate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
AKL65780.1Alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (239 aa)
AKL65851.1Cysteine desulfurase; Belongs to the sulfur carrier protein TusA family. (460 aa)
AKL66147.1Amino acid decarboxylase. (467 aa)
AKL66201.13D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. (622 aa)
AKL66217.1Acetolactate synthase; Belongs to the TPP enzyme family. (546 aa)
AKL66231.1Pyridoxal-dependent decarboxylase. (499 aa)
AKL66339.1Oxidoreductase; Belongs to the iron/ascorbate-dependent oxidoreductase family. (333 aa)
AKL66405.1Diaminopimelate decarboxylase. (458 aa)
AKL66480.1Aminotransferase class I and II. (424 aa)
Your Current Organism:
Streptomyces sp. Mg1
NCBI taxonomy Id: 465541
Other names: S. sp. Mg1
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