STRINGSTRING
AKL64173.1 AKL64173.1 AKL64367.1 AKL64367.1 AKL64553.1 AKL64553.1 AKL65024.1 AKL65024.1 AKL65074.1 AKL65074.1 AKL65094.1 AKL65094.1 AKL65124.1 AKL65124.1 AKL65164.1 AKL65164.1 hisG hisG hisE hisE AKL65286.1 AKL65286.1 metK metK aroQ aroQ aroB aroB aroK aroK aroC aroC AKL65313.1 AKL65313.1 AKL65358.1 AKL65358.1 argH argH argG argG argD argD argB argB argJ argJ argC argC AKL65414.1 AKL65414.1 AKL65448.1 AKL65448.1 AKL65533.1 AKL65533.1 AKL65578.1 AKL65578.1 AKL69904.1 AKL69904.1 dapD dapD AKL65652.1 AKL65652.1 tal tal tpiA tpiA pgk pgk AKL65661.1 AKL65661.1 AKL65704.1 AKL65704.1 AKL65709.1 AKL65709.1 gltD gltD AKL65737.1 AKL65737.1 AKL65745.1 AKL65745.1 AKL65746.1 AKL65746.1 AKL65747.1 AKL65747.1 trpE trpE hisI hisI hisF hisF priA-2 priA-2 hisH hisH hisB hisB hisC hisC hisD hisD AKL65817.1 AKL65817.1 pfp pfp trpD trpD AKL65881.1 AKL65881.1 AKL65896.1 AKL65896.1 AKL65921.1 AKL65921.1 leuA leuA proA proA proB proB AKL66152.1 AKL66152.1 asd asd AKL66210.1 AKL66210.1 AKL66217.1 AKL66217.1 AKL66405.1 AKL66405.1 AKL70031.1 AKL70031.1 eno eno prs prs AKL66476.1 AKL66476.1 gltD-2 gltD-2 AKL66611.1 AKL66611.1 AKL66641.1 AKL66641.1 AKL66652.1 AKL66652.1 trpF trpF AKL66690.1 AKL66690.1 gpmA gpmA AKL66877.1 AKL66877.1 pat pat AKL66903.1 AKL66903.1 AKL66906.1 AKL66906.1 aroK-2 aroK-2 aroC-2 aroC-2 aroA aroA AKL67040.1 AKL67040.1 AKL67100.1 AKL67100.1 AKL67105.1 AKL67105.1 AKL67135.1 AKL67135.1 AKL67136.1 AKL67136.1 AKL67248.1 AKL67248.1 ilvD ilvD AKL67270.1 AKL67270.1 AKL67394.1 AKL67394.1 AKL67479.1 AKL67479.1 glyA glyA AKL67590.1 AKL67590.1 AKL67594.1 AKL67594.1 AKL67608.1 AKL67608.1 AKL67682.1 AKL67682.1 AKL67717.1 AKL67717.1 AKL67722.1 AKL67722.1 AKL67779.1 AKL67779.1 aroA-2 aroA-2 lysA lysA AKL70248.1 AKL70248.1 AKL67882.1 AKL67882.1 thrB thrB glyA-2 glyA-2 hisG-2 hisG-2 proB-2 proB-2 proC proC AKL67941.1 AKL67941.1 pfkA pfkA AKL67979.1 AKL67979.1 glyA-3 glyA-3 AKL68015.1 AKL68015.1 AKL68016.1 AKL68016.1 ilvC ilvC AKL68018.1 AKL68018.1 leuB leuB AKL68029.1 AKL68029.1 AKL68036.1 AKL68036.1 leuC leuC leuD leuD AKL68122.1 AKL68122.1 AKL68193.1 AKL68193.1 dapA dapA dapF dapF AKL70297.1 AKL70297.1 AKL68267.1 AKL68267.1 AKL68268.1 AKL68268.1 AKL68347.1 AKL68347.1 acnA acnA AKL68470.1 AKL68470.1 AKL68610.1 AKL68610.1 AKL68678.1 AKL68678.1 AKL68679.1 AKL68679.1 pfkA-2 pfkA-2 AKL68768.1 AKL68768.1 AKL68922.1 AKL68922.1 AKL68924.1 AKL68924.1 lysA-2 lysA-2 AKL69058.1 AKL69058.1 AKL69340.1 AKL69340.1 AKL69377.1 AKL69377.1 AKL69384.1 AKL69384.1 AKL70513.1 AKL70513.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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AKL64173.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor. (404 aa)
AKL64367.1Transketolase; Belongs to the transketolase family. (739 aa)
AKL64553.1Asparagine synthase. (614 aa)
AKL65024.1Fructose-bisphosphate aldolase. (278 aa)
AKL65074.1Cysteine synthase. (381 aa)
AKL65094.1Threonine aldolase. (353 aa)
AKL65124.1Threonine dehydratase. (311 aa)
AKL65164.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Belongs to the monomeric-type IDH family. (739 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (282 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis. (93 aa)
AKL65286.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (160 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa)
AKL65313.1Shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. (274 aa)
AKL65358.1Class IV aminotransferase. (273 aa)
argHArgininosuccinate lyase. (476 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (397 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (407 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (288 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (385 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa)
AKL65414.1Glutamine synthetase. (454 aa)
AKL65448.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1170 aa)
AKL65533.1Prephenate dehydrogenase. (362 aa)
AKL65578.1Phosphoserine phosphatase. (399 aa)
AKL69904.1Aminotransferase. (352 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (326 aa)
AKL65652.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (700 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Belongs to the phosphoglycerate kinase family. (403 aa)
AKL65661.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
AKL65704.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. (475 aa)
AKL65709.1Chorismate mutase. (106 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate. (486 aa)
AKL65737.1Glutamate synthase. (1536 aa)
AKL65745.1Tryptophan synthase subunit alpha. (270 aa)
AKL65746.1Tryptophan synthase subunit beta; Catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate. (414 aa)
AKL65747.1Indole-3-glycerol phosphate synthase. (269 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (500 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (121 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
priA-2Phosphoribosyl isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (243 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
hisBImidazoleglycerol-phosphate dehydratase. (197 aa)
hisCAspartate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa)
AKL65817.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (451 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (354 aa)
AKL65881.1Glutamine synthetase. (469 aa)
AKL65896.1Glutamine synthetase. (339 aa)
AKL65921.1Glutamine synthetase. (453 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (590 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (425 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (375 aa)
AKL66152.1Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity. (161 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa)
AKL66210.1Citrate synthase; Belongs to the citrate synthase family. (429 aa)
AKL66217.1Acetolactate synthase; Belongs to the TPP enzyme family. (546 aa)
AKL66405.1Diaminopimelate decarboxylase. (458 aa)
AKL70031.1Cystathionine beta-synthase. (460 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
AKL66476.1Ornithine cyclodeaminase. (315 aa)
gltD-2Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate. (524 aa)
AKL66611.1Dihydrodipicolinate synthetase. (262 aa)
AKL66641.1Citrate synthase 2; Forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; Belongs to the citrate synthase family. (368 aa)
AKL66652.1Phosphoserine aminotransferase. (373 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (205 aa)
AKL66690.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine. (424 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
AKL66877.1Prephenate dehydratase. (311 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (360 aa)
AKL66903.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine. (387 aa)
AKL66906.1Hydrolase. (216 aa)
aroK-2Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa)
aroC-2Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (441 aa)
AKL67040.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (388 aa)
AKL67100.1Aminotransferase. (392 aa)
AKL67105.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
AKL67135.1Aspartate kinase; Belongs to the aspartokinase family. (424 aa)
AKL67136.1Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (357 aa)
AKL67248.1N-acetylglutamate synthase; Belongs to the acetyltransferase family. (176 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Belongs to the IlvD/Edd family. (616 aa)
AKL67270.1Pyrroline-5-carboxylate reductase. (269 aa)
AKL67394.1Aspartate aminotransferase. (408 aa)
AKL67479.1Chorismate mutase. (86 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
AKL67590.1Cystathionine gamma-synthase. (385 aa)
AKL67594.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine. (410 aa)
AKL67608.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor. (403 aa)
AKL67682.1Pyridoxal-5'-phosphate-dependent protein subunit beta. (370 aa)
AKL67717.1Acetyltransferase. (327 aa)
AKL67722.1Succinyl-diaminopimelate desuccinylase; Catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate. (359 aa)
AKL67779.1Histidinol phosphatase. (268 aa)
aroA-23-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (450 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
AKL70248.1Homoserine dehydrogenase. (433 aa)
AKL67882.1L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (356 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa)
hisG-2ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (284 aa)
proB-2Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (380 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
AKL67941.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. (477 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
AKL67979.1Serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (460 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
AKL68015.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate. (626 aa)
AKL68016.1Acetolactate synthase. (174 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
AKL68018.13-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (346 aa)
AKL68029.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids. (361 aa)
AKL68036.1Transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (541 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
AKL68122.1Hypothetical protein. (588 aa)
AKL68193.1Dihydrodipicolinate reductase. (251 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (291 aa)
AKL70297.12,4-diaminobutyrate 4-aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
AKL68267.1Citrate synthase. (419 aa)
AKL68268.1Citrate (Si)-synthase; Belongs to the citrate synthase family. (388 aa)
AKL68347.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (340 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
AKL68470.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (777 aa)
AKL68610.1Glyceraldehyde-3-phosphate dehydrogenase. (480 aa)
AKL68678.1Transketolase. (314 aa)
AKL68679.1Transketolase. (233 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (342 aa)
AKL68768.1Aspartate aminotransferase. (396 aa)
AKL68922.1Phosphoglycerate mutase. (238 aa)
AKL68924.1Methionine adenosyltransferase. (415 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (444 aa)
AKL69058.1Dihydrodipicolinate synthase; Belongs to the DapA family. (307 aa)
AKL69340.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
AKL69377.1Argininosuccinate lyase. (498 aa)
AKL69384.1Threonine aldolase. (348 aa)
AKL70513.1Hypothetical protein. (314 aa)
Your Current Organism:
Streptomyces sp. Mg1
NCBI taxonomy Id: 465541
Other names: S. sp. Mg1
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