STRINGSTRING
AMN45656.1 AMN45656.1 fadB fadB proC proC AMN45947.1 AMN45947.1 AMN46137.1 AMN46137.1 AMN46247.1 AMN46247.1 AMN46369.1 AMN46369.1 AMN46414.1 AMN46414.1 AMN46421.1 AMN46421.1 AMN46443.1 AMN46443.1 AMN46561.1 AMN46561.1 AMN46999.1 AMN46999.1 ilvC ilvC gpsA gpsA
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMN45656.13-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (693 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; 'includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids'. (714 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)
AMN45947.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (335 aa)
AMN46137.1Chorismate mutase / prephenate dehydrogenase. (369 aa)
AMN46247.13-hydroxyisobutyrate dehydrogenase. (284 aa)
AMN46369.13-hydroxyacyl-CoA dehydrogenase. (715 aa)
AMN46414.1UDP-N-acetyl-D-galactosamine dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (427 aa)
AMN46421.1Opine dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (363 aa)
AMN46443.1UDP-glucose 6-dehydrogenase. (444 aa)
AMN46561.16-phosphogluconate dehydrogenase. (331 aa)
AMN46999.13-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase. (681 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (344 aa)
Your Current Organism:
Steroidobacter denitrificans
NCBI taxonomy Id: 465721
Other names: DSM 18526, JCM 14622, S. denitrificans, Steroidobacter denitrificans Fahrbach et al. 2008, gamma proteobacterium FS-2007, strain FS
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