STRINGSTRING
AMB83891.1 AMB83891.1 AMB83893.1 AMB83893.1 AMB83984.1 AMB83984.1 AMB84010.1 AMB84010.1 hslO hslO AMB84141.1 AMB84141.1 AMB84142.1 AMB84142.1 rimK rimK AMB84176.1 AMB84176.1 AWM79_02245 AWM79_02245 AMB84296.1 AMB84296.1 AMB84383.1 AMB84383.1 AMB84667.1 AMB84667.1 AMB85031.1 AMB85031.1 AMB85032.1 AMB85032.1 AMB85116.1 AMB85116.1 AMB85174.1 AMB85174.1 AMB85207.1 AMB85207.1 AMB85257.1 AMB85257.1 alaS alaS groEL groEL groS groS lon lon AMB85647.1 AMB85647.1 AMB85740.1 AMB85740.1 rapA rapA AMB86086.1 AMB86086.1 katE katE AMB86255.1 AMB86255.1 AMB86382.1 AMB86382.1 AMB86425.1 AMB86425.1 AWM79_15165 AWM79_15165 AMB86603.1 AMB86603.1 AMB86622.1 AMB86622.1 clpB clpB AMB86918.1 AMB86918.1 AMB86919.1 AMB86919.1 hscA hscA hslV hslV hslU hslU htpG htpG AMB87103.1 AMB87103.1 dnaJ dnaJ dnaK dnaK grpE grpE fur-2 fur-2 AMB87339.1 AMB87339.1 AMB87340.1 AMB87340.1 AMB87341.1 AMB87341.1 AMB87412.1 AMB87412.1 AWM79_19975 AWM79_19975 AMB87635.1 AMB87635.1 AMB87709.1 AMB87709.1 AMB88382.1 AMB88382.1 lon-2 lon-2 clpX clpX clpP clpP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMB83891.1Pyrroloquinoline quinone biosynthesis protein PqqF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family. (821 aa)
AMB83893.1Amine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
AMB83984.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (482 aa)
AMB84010.1Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
hslOMolecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. (300 aa)
AMB84141.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. (134 aa)
AMB84142.1Ribosomal protein S6 modification protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
rimKRibosomal protein S6 modification protein; Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family. (301 aa)
AMB84176.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (109 aa)
AWM79_02245Transcriptional regulator; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
AMB84296.1Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AMB84383.1Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
AMB84667.1Glutathione reductase; Maintains high levels of reduced glutathione. (452 aa)
AMB85031.1Alkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
AMB85032.1Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
AMB85116.1Peptidase C13; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
AMB85174.1Glucose-methanol-choline oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
AMB85207.1Type III effector HopAC1; Derived by automated computational analysis using gene prediction method: Protein Homology. (1875 aa)
AMB85257.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (874 aa)
groELMolecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (548 aa)
groSMolecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (97 aa)
lonLon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (810 aa)
AMB85647.1Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AMB85740.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (869 aa)
rapARNA polymerase-binding ATPase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (948 aa)
AMB86086.1ClpV1 family T6SS ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (874 aa)
katECatalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide. (717 aa)
AMB86255.1Choline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
AMB86382.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
AMB86425.1Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AWM79_15165Integrase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
AMB86603.1Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AMB86622.1Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (854 aa)
AMB86918.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (508 aa)
AMB86919.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
hscAMolecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa)
hslVATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (176 aa)
hslUATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (445 aa)
htpGMolecular chaperone HtpG; Molecular chaperone. Has ATPase activity. (634 aa)
AMB87103.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (374 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (638 aa)
grpEMolecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] (188 aa)
fur-2Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (134 aa)
AMB87339.1Chaperone modulatory protein CbpM; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AMB87340.1DNA-binding protein; Functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
AMB87341.1Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
AMB87412.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
AWM79_19975Transcriptional regulator; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AMB87635.1Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. (149 aa)
AMB87709.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
AMB88382.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
lon-2DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (798 aa)
clpXATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (427 aa)
clpPATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (211 aa)
Your Current Organism:
Pseudomonas agarici
NCBI taxonomy Id: 46677
Other names: ATCC 25941, CCUG 32769, CFBP 2063, CIP 106703, DSM 11810, ICMP 2656, JCM 12566, LMG 2112, LMG:2112, NCPPB 2289, P. agarici
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