(65 nodes) Positive regulation of proteolysis network (Fasciola gigantica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGIG_05594	WD repeat-containing protein 48. (808 aa)
	FGIG_10414	Protein kinase. (405 aa)
	FGIG_11082	Uncharacterized protein. (124 aa)
	FGIG_07389	Putative Glycogen synthase kinase. (207 aa)
	FGIG_02557	Proteasome (Prosome macropain) 26S subunit ATPase 5; Belongs to the AAA ATPase family. (430 aa)
	FGIG_10215	Fizzy protein. (667 aa)
	FGIG_06060	Uncharacterized protein. (168 aa)
	FGIG_01174	26S protease regulatory subunit 7. (96 aa)
	FGIG_05067	Putative sorbin. (882 aa)
	FGIG_02559	26S protease regulatory subunit 7. (76 aa)
	FGIG_08670	Casein kinase I delta. (611 aa)
	FGIG_08349	CMGC/GSK protein kinase. (390 aa)
	FGIG_03696	PRELI domain-containing protein 1 mitochondrial. (222 aa)
	FGIG_03693	Proteasome (Prosome macropain) 26S subunit ATPase 3; Belongs to the AAA ATPase family. (422 aa)
	FGIG_07070	26S protease regulatory subunit 7. (171 aa)
	FGIG_05474	RBR-type E3 ubiquitin transferase. (477 aa)
	FGIG_02449	Adhesion regulating molecule 1. (394 aa)
	FGIG_01141	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	FGIG_06900	STIP1 and U box-containing protein 1. (1888 aa)
	FGIG_07571	Putative Axis inhibition protein axin. (824 aa)
	FGIG_01053	RGS domain-containing protein. (840 aa)
	FGIG_04055	Bardet-Biedl syndrome 7 protein. (748 aa)
	FGIG_06061	Uncharacterized protein. (224 aa)
	FGIG_02742	TNFR_16_TM domain-containing protein. (367 aa)
	FGIG_11361	Squamous cell carcinoma antigen recognized by T-cells 3. (512 aa)
	FGIG_11746	Huntington inteteracting protein. (251 aa)
	FGIG_12559	Uncharacterized protein. (170 aa)
	FGIG_04527	Proteasome 26S subunit subunit 4 ATPase; Belongs to the AAA ATPase family. (436 aa)
	FGIG_04819	Uncharacterized protein. (142 aa)
	FGIG_12279	Putative apoptosis regulator bax. (195 aa)
	FGIG_05072	26S protease regulatory subunit 7. (118 aa)
	FGIG_06090	Uncharacterized protein. (485 aa)
	FGIG_11449	ATP-dependent Clp protease ATP-binding subunit ClpX. (581 aa)
	FGIG_09346	RBR-type E3 ubiquitin transferase. (432 aa)
	FGIG_12345	26S protease regulatory subunit 7. (132 aa)
	FGIG_02761	Rhomboid domain-containing protein 1. (262 aa)
	FGIG_11754	26S proteasome non-ATPase regulatory subunit 10. (412 aa)
	FGIG_03557	Bcl-2 ous antagonist/killer. (115 aa)
	FGIG_05367	PRA1 family protein. (173 aa)
	FGIG_01419	RBR-type E3 ubiquitin transferase. (545 aa)
	FGIG_04858	Transmembrane protein. (419 aa)
	FGIG_11735	Fizzy protein. (468 aa)
	FGIG_06776	F-box and WD-40 domain protein 1/11. (896 aa)
	FGIG_06318	Ubiquitin carboxyl-terminal hydrolase. (925 aa)
	FGIG_10998	Proteasome (Prosome macropain) 26S subunit ATPase 6. (371 aa)
	FGIG_10013	Uncharacterized protein. (89 aa)
	FGIG_10836	Huntingtin-interacting protein 1. (517 aa)
	FGIG_10017	Proteasome activator complex subunit 3. (273 aa)
	FGIG_08424	Cell division cycle 20 cofactor of APC complex. (447 aa)
	FGIG_07289	Expressed conserved protein. (159 aa)
	FGIG_08057	Proteasome (Prosome macropain) 26S subunit ATPase 4; Belongs to the AAA ATPase family. (415 aa)
	FGIG_07741	Uncharacterized protein. (703 aa)
	FGIG_11721	RING-type domain-containing protein. (215 aa)
	FGIG_04631	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	FGIG_05093	Glycogen synthase kinase. (347 aa)
	FGIG_01963	Putative atp-dependent 26s proteasome regulatory subunit posttranslational modification. (290 aa)
	FGIG_07267	WD_REPEATS_REGION domain-containing protein. (350 aa)
	FGIG_08042	ERAD-associated E3 ubiquitin-protein ligase HRD1B. (540 aa)
	FGIG_07275	Proteasome activator complex subunit 3. (228 aa)
	FGIG_02755	Uncharacterized protein. (855 aa)
	FGIG_02537	Uncharacterized protein. (261 aa)
	FGIG_05147	RBR-type E3 ubiquitin transferase. (404 aa)
	FGIG_12522	26S protease regulatory subunit 10B. (117 aa)
	FGIG_07690	RBR-type E3 ubiquitin transferase. (550 aa)
	FGIG_06088	Uncharacterized protein. (549 aa)

Your Current Organism:

Fasciola gigantica

NCBI taxonomy Id: 46835
Other names: F. gigantica

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGIG_01053	FGIG_01174	A0A504YZV5	A0A504YS76	RGS domain-containing protein.	26S protease regulatory subunit 7.	0.465
FGIG_01053	FGIG_01963	A0A504YZV5	A0A504YFK4	RGS domain-containing protein.	Putative atp-dependent 26s proteasome regulatory subunit posttranslational modification.	0.465
FGIG_01053	FGIG_02557	A0A504YZV5	A0A504YPG9	RGS domain-containing protein.	Proteasome (Prosome macropain) 26S subunit ATPase 5; Belongs to the AAA ATPase family.	0.528
FGIG_01053	FGIG_02559	A0A504YZV5	A0A504YSS5	RGS domain-containing protein.	26S protease regulatory subunit 7.	0.465
FGIG_01053	FGIG_04527	A0A504YZV5	A0A504Z1X5	RGS domain-containing protein.	Proteasome 26S subunit subunit 4 ATPase; Belongs to the AAA ATPase family.	0.558
FGIG_01053	FGIG_04819	A0A504YZV5	A0A504Z3K6	RGS domain-containing protein.	Uncharacterized protein.	0.465
FGIG_01053	FGIG_05072	A0A504YZV5	A0A504Z4P0	RGS domain-containing protein.	26S protease regulatory subunit 7.	0.465
FGIG_01053	FGIG_05093	A0A504YZV5	A0A504YEY9	RGS domain-containing protein.	Glycogen synthase kinase.	0.862
FGIG_01053	FGIG_06088	A0A504YZV5	A0A504YJR2	RGS domain-containing protein.	Uncharacterized protein.	0.507
FGIG_01053	FGIG_06776	A0A504YZV5	A0A504Y4Y0	RGS domain-containing protein.	F-box and WD-40 domain protein 1/11.	0.885
FGIG_01053	FGIG_07070	A0A504YZV5	A0A504YWH5	RGS domain-containing protein.	26S protease regulatory subunit 7.	0.465
FGIG_01053	FGIG_07389	A0A504YZV5	A0A504YM50	RGS domain-containing protein.	Putative Glycogen synthase kinase.	0.862
FGIG_01053	FGIG_07571	A0A504YZV5	A0A504YZL7	RGS domain-containing protein.	Putative Axis inhibition protein axin.	0.931
FGIG_01053	FGIG_08349	A0A504YZV5	A0A504YTZ4	RGS domain-containing protein.	CMGC/GSK protein kinase.	0.862
FGIG_01053	FGIG_08670	A0A504YZV5	A0A504YTA9	RGS domain-containing protein.	Casein kinase I delta.	0.927
FGIG_01053	FGIG_10414	A0A504YZV5	A0A504YKL1	RGS domain-containing protein.	Protein kinase.	0.507
FGIG_01053	FGIG_11082	A0A504YZV5	A0A504YKS7	RGS domain-containing protein.	Uncharacterized protein.	0.465
FGIG_01053	FGIG_11754	A0A504YZV5	A0A504ZBT1	RGS domain-containing protein.	26S proteasome non-ATPase regulatory subunit 10.	0.632
FGIG_01053	FGIG_12345	A0A504YZV5	A0A504Z8G7	RGS domain-containing protein.	26S protease regulatory subunit 7.	0.465
FGIG_01141	FGIG_03557	A0A504YY43	A0A504YA45	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Bcl-2 ous antagonist/killer.	0.839