(10 nodes) FCERI mediated NF-kB activation network (Fasciola gigantica)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	FGIG_02925	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1230 aa)
	FGIG_04727	Proteasome subunit beta. (267 aa)
	FGIG_03693	Proteasome (Prosome macropain) 26S subunit ATPase 3; Belongs to the AAA ATPase family. (422 aa)
	FGIG_11723	Small subunit ribosomal protein S27Ae. (149 aa)
	FGIG_04163	Proteasome subunit beta. (293 aa)
	FGIG_03983	26S proteasome non-ATPase regulatory subunit. (375 aa)
	FGIG_08506	Polyubiquitin. (192 aa)
	FGIG_12152	Polyubiquitine protein. (136 aa)
	FGIG_02408	Proteasome endopeptidase complex. (176 aa)
	FGIG_06776	F-box and WD-40 domain protein 1/11. (896 aa)

Your Current Organism:

Fasciola gigantica

NCBI taxonomy Id: 46835
Other names: F. gigantica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGIG_02408	FGIG_02925	A0A504Y8I5	A0A504Z300	Proteasome endopeptidase complex.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.992
FGIG_02408	FGIG_03693	A0A504Y8I5	A0A504YV76	Proteasome endopeptidase complex.	Proteasome (Prosome macropain) 26S subunit ATPase 3; Belongs to the AAA ATPase family.	0.994
FGIG_02408	FGIG_03983	A0A504Y8I5	A0A504WSR5	Proteasome endopeptidase complex.	26S proteasome non-ATPase regulatory subunit.	0.996
FGIG_02408	FGIG_04163	A0A504Y8I5	A0A504YTP8	Proteasome endopeptidase complex.	Proteasome subunit beta.	0.999
FGIG_02408	FGIG_04727	A0A504Y8I5	A0A504YZ89	Proteasome endopeptidase complex.	Proteasome subunit beta.	0.999
FGIG_02408	FGIG_08506	A0A504Y8I5	A0A504YHV3	Proteasome endopeptidase complex.	Polyubiquitin.	0.943
FGIG_02408	FGIG_11723	A0A504Y8I5	A0A504Z6K4	Proteasome endopeptidase complex.	Small subunit ribosomal protein S27Ae.	0.970
FGIG_02408	FGIG_12152	A0A504Y8I5	A0A504YBE5	Proteasome endopeptidase complex.	Polyubiquitine protein.	0.939
FGIG_02925	FGIG_02408	A0A504Z300	A0A504Y8I5	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome endopeptidase complex.	0.992
FGIG_02925	FGIG_03693	A0A504Z300	A0A504YV76	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome (Prosome macropain) 26S subunit ATPase 3; Belongs to the AAA ATPase family.	0.998
FGIG_02925	FGIG_03983	A0A504Z300	A0A504WSR5	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	26S proteasome non-ATPase regulatory subunit.	0.999
FGIG_02925	FGIG_04163	A0A504Z300	A0A504YTP8	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome subunit beta.	0.991
FGIG_02925	FGIG_04727	A0A504Z300	A0A504YZ89	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome subunit beta.	0.989
FGIG_02925	FGIG_06776	A0A504Z300	A0A504Y4Y0	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	F-box and WD-40 domain protein 1/11.	0.459
FGIG_02925	FGIG_08506	A0A504Z300	A0A504YHV3	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Polyubiquitin.	0.962
FGIG_02925	FGIG_11723	A0A504Z300	A0A504Z6K4	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Small subunit ribosomal protein S27Ae.	0.983
FGIG_02925	FGIG_12152	A0A504Z300	A0A504YBE5	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Polyubiquitine protein.	0.960
FGIG_03693	FGIG_02408	A0A504YV76	A0A504Y8I5	Proteasome (Prosome macropain) 26S subunit ATPase 3; Belongs to the AAA ATPase family.	Proteasome endopeptidase complex.	0.994
FGIG_03693	FGIG_02925	A0A504YV76	A0A504Z300	Proteasome (Prosome macropain) 26S subunit ATPase 3; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.998
FGIG_03693	FGIG_03983	A0A504YV76	A0A504WSR5	Proteasome (Prosome macropain) 26S subunit ATPase 3; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit.	0.999