(24 nodes) Regulation of TP53 Expression and Degradation network (Fasciola gigantica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGIG_08515	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2492 aa)
	FGIG_12152	Polyubiquitine protein. (136 aa)
	FGIG_00424	Death domain-associated protein 6. (92 aa)
	FGIG_02712	Protein kinase B. (278 aa)
	FGIG_08298	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (787 aa)
	FGIG_08506	Polyubiquitin. (192 aa)
	FGIG_01822	Serine/threonine-protein phosphatase. (318 aa)
	FGIG_10964	3-phosphoinositide-dependent protein kinase. (504 aa)
	FGIG_11268	G beta protein gbl. (212 aa)
	FGIG_04836	Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1424 aa)
	FGIG_12496	RasGEF_N_2 domain-containing protein. (183 aa)
	FGIG_04927	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2401 aa)
	FGIG_04926	Uncharacterized protein. (273 aa)
	FGIG_07303	RICTOR_N domain-containing protein. (1524 aa)
	FGIG_00149	Ribosomal_L7Ae domain-containing protein. (486 aa)
	FGIG_00421	Death domain-associated protein 6. (682 aa)
	FGIG_05729	Target of rapamycin complex 2 subunit MAPKAP1. (632 aa)
	FGIG_11519	Uncharacterized protein. (322 aa)
	FGIG_11723	Small subunit ribosomal protein S27Ae. (149 aa)
	FGIG_12593	Uncharacterized protein. (172 aa)
	FGIG_10421	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (504 aa)
	FGIG_03866	PRDM1. (811 aa)
	FGIG_12370	Uncharacterized protein. (293 aa)
	FGIG_00552	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta. (211 aa)

Your Current Organism:

Fasciola gigantica

NCBI taxonomy Id: 46835
Other names: F. gigantica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGIG_00421	FGIG_01822	A0A504Y425	A0A504YI98	Death domain-associated protein 6.	Serine/threonine-protein phosphatase.	0.473
FGIG_00421	FGIG_02712	A0A504Y425	A0A504YFF9	Death domain-associated protein 6.	Protein kinase B.	0.562
FGIG_00421	FGIG_04836	A0A504Y425	A0A504YL48	Death domain-associated protein 6.	Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family.	0.913
FGIG_00421	FGIG_08506	A0A504Y425	A0A504YHV3	Death domain-associated protein 6.	Polyubiquitin.	0.648
FGIG_00421	FGIG_11723	A0A504Y425	A0A504Z6K4	Death domain-associated protein 6.	Small subunit ribosomal protein S27Ae.	0.647
FGIG_00421	FGIG_12152	A0A504Y425	A0A504YBE5	Death domain-associated protein 6.	Polyubiquitine protein.	0.645
FGIG_00424	FGIG_01822	A0A504YDK6	A0A504YI98	Death domain-associated protein 6.	Serine/threonine-protein phosphatase.	0.473
FGIG_00424	FGIG_02712	A0A504YDK6	A0A504YFF9	Death domain-associated protein 6.	Protein kinase B.	0.562
FGIG_00424	FGIG_04836	A0A504YDK6	A0A504YL48	Death domain-associated protein 6.	Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family.	0.913
FGIG_00424	FGIG_08506	A0A504YDK6	A0A504YHV3	Death domain-associated protein 6.	Polyubiquitin.	0.648
FGIG_00424	FGIG_11723	A0A504YDK6	A0A504Z6K4	Death domain-associated protein 6.	Small subunit ribosomal protein S27Ae.	0.647
FGIG_00424	FGIG_12152	A0A504YDK6	A0A504YBE5	Death domain-associated protein 6.	Polyubiquitine protein.	0.645
FGIG_00552	FGIG_01822	A0A504YRY7	A0A504YI98	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta.	Serine/threonine-protein phosphatase.	0.995
FGIG_00552	FGIG_02712	A0A504YRY7	A0A504YFF9	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta.	Protein kinase B.	0.816
FGIG_00552	FGIG_08298	A0A504YRY7	A0A504YHM1	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform.	0.910
FGIG_00552	FGIG_08506	A0A504YRY7	A0A504YHV3	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta.	Polyubiquitin.	0.641
FGIG_00552	FGIG_11723	A0A504YRY7	A0A504Z6K4	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta.	Small subunit ribosomal protein S27Ae.	0.580
FGIG_00552	FGIG_12152	A0A504YRY7	A0A504YBE5	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta.	Polyubiquitine protein.	0.560
FGIG_01822	FGIG_00421	A0A504YI98	A0A504Y425	Serine/threonine-protein phosphatase.	Death domain-associated protein 6.	0.473
FGIG_01822	FGIG_00424	A0A504YI98	A0A504YDK6	Serine/threonine-protein phosphatase.	Death domain-associated protein 6.	0.473